| ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding. Dunlop E.A., Hunt D.K., Acosta-Jaquez H.A., Fingar D.C., Tee A.R.
Autophagy 7:737-747(2011) · Mapped (12) |
| Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock. Scott C.L., Walker D.J., Cwiklinski E., Tait C., Tee A.R., Land S.C.
Am. J. Physiol. Lung Cell Mol. Physiol. 299:L455-71(2010) · Mapped (22) |
| mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action. Soliman G.A., Acosta-Jaquez H.A., Dunlop E.A., Ekim B., Maj N.E., Tee A.R., Fingar D.C.
J. Biol. Chem. 285:7866-7879(2010) · Mapped (8) |
| Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning. Cai S.L., Tee A.R., Short J.D., Bergeron J.M., Kim J., Shen J., Guo R., Johnson C.L., Kiguchi K., Walker C.L.
J. Cell Biol. 173:279-289(2006) |
| Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1. Tee A.R., Blenis J., Proud C.G.
FEBS Lett. 579:4763-4768(2005) · UniProtKB (2) · Mapped (3) |
| The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses. Smith E.M., Finn S.G., Tee A.R., Browne G.J., Proud C.G.
J. Biol. Chem. 280:18717-18727(2005) · Mapped (15) |
| Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation. Schalm S.S., Tee A.R., Blenis J.
J. Biol. Chem. 280:11101-11106(2005) · Mapped (13) |
| Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1. Tee A.R., Tee J.A., Blenis J.
FEBS Lett. 564:58-62(2004) · Mapped (6) |
| mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Fingar D.C., Richardson C.J., Tee A.R., Cheatham L., Tsou C., Blenis J.
Mol. Cell. Biol. 24:200-216(2004) · UniProtKB (1) |
| Localisation and regulation of the eIF4E-binding protein 4E-BP3. Kleijn M., Scheper G.C., Wilson M.L., Tee A.R., Proud C.G.
FEBS Lett. 532:319-323(2002) · Mapped (3) |
| Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Tee A.R., Fingar D.C., Manning B.D., Kwiatkowski D.J., Cantley L.C., Blenis J.
Proc. Natl. Acad. Sci. U.S.A. 99:13571-13576(2002) · UniProtKB (3) · Mapped (6) |
| Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Manning B.D., Tee A.R., Logsdon M.N., Blenis J., Cantley L.C.
Mol. Cell 10:151-162(2002) · UniProtKB (2) · Mapped (15) |
| Caspase cleavage of initiation factor 4E-binding protein 1 yields a dominant inhibitor of cap-dependent translation and reveals a novel regulatory motif. Tee A.R., Proud C.G.
Mol. Cell. Biol. 22:1674-1683(2002) · Mapped (1) |
