| AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. Agarwal A.K., Arioglu E., de Almeida S., Akkoc N., Taylor S.I., Bowcock A.M., Barnes R.I., Garg A.
Nat. Genet. 31:21-23(2002) · UniProtKB (2) · Mapped (7) |
| Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. Parks W.T., Frank D.B., Huff C., Haft C.R., Martin J., Meng X., de Caestecker M.P., McNally J.G., Reddi A., Taylor S.I. et al.
J. Biol. Chem. 276:19332-19339(2001) · UniProtKB (1) |
| Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. Renfrew Haft C., de la Luz Sierra M., Bafford R., Lesniak M.A., Barr V.A., Taylor S.I.
Mol. Biol. Cell 11:4105-4116(2000) · UniProtKB (3) · Mapped (3) |
| Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin. Perrotti N., He R.A., Phillips S.A., Haft C.R., Taylor S.I.
J. Biol. Chem. 276:9406-9412(2001) · UniProtKB (1) |
| Identification and characterization of snx15, a novel sorting nexin involved in protein trafficking. Phillips S.A., Barr V.A., Haft D.H., Taylor S.I., Haft C.R.
J. Biol. Chem. 276:5074-5084(2001) · UniProtKB (1) · Mapped (10) |
| Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Kubota N., Tobe K., Terauchi Y., Eto K., Yamauchi T., Suzuki R., Tsubamoto Y., Komeda K., Nakano R., Miki H. et al.
Diabetes 49:1880-1889(2000) · Mapped (4) |
| Characterization of Drosophila insulin receptor substrate. Poltilove R.M.K., Jacobs A.R., Haft C.R., Xu P., Taylor S.I.
J. Biol. Chem. 275:23346-23354(2000) · UniProtKB (1) · Mapped (20) |
| Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/C. Speckman R.A., Garg A., Du F., Bennett L., Veile R., Arioglu E., Taylor S.I., Lovett M., Bowcock A.M.
Am. J. Hum. Genet. 66:1192-1198(2000) · UniProtKB (1) |
| Deconstructing type 2 diabetes. Taylor S.I.
Cell 97:9-12(1999) · Mapped (5) |
| Identification of a family of sorting nexin molecules and characterization of their association with receptors. Haft C.R., de la Luz Sierra M., Barr V.A., Haft D.H., Taylor S.I.
Mol. Cell. Biol. 18:7278-7287(1998) · UniProtKB (4) · Mapped (2) |
| Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Cong L.N., Chen H., Li Y., Zhou L., McGibbon M.A., Taylor S.I., Quon M.J.
Mol. Endocrinol. 11:1881-1890(1997) · UniProtKB (1) · Mapped (5) |
| Cloning, tissue expression, and chromosomal localization of the mouse IRS-3 gene. Sciacchitano S., Taylor S.I.
Endocrinology 138:4931-4940(1997) · UniProtKB (1) · Mapped (3) |
| Four mutant alleles of the insulin receptor gene associated with genetic syndromes of extreme insulin resistance. Kadowaki H., Takahashi Y., Ando A., Momomura K., Kaburagi Y., Quin J.D., MacCuish A.C., Koda N., Fukushima Y., Taylor S.I. et al.
Biochem. Biophys. Res. Commun. 237:516-520(1997) · UniProtKB (1) |
| Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Bruning J.C., Winnay J., Bonner-Weir S., Taylor S.I., Accili D., Kahn C.R.
Cell 88:561-572(1997) · Mapped (7) |
| Cloning of the chicken insulin receptor substrate 1 gene. Taouis M., Taylor S.I., Reitman M.
Gene 178:51-55(1996) · UniProtKB (1) · Mapped (2) |
| Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Accili D., Drago J., Lee E.J., Johnson M.D., Cool M.H., Salvatore P., Asico L.D., Jose P.A., Taylor S.I., Westphal H.
Nat. Genet. 12:106-109(1996) · Mapped (5) |
| Antibodies to the extracellular receptor domain restore the hormone-insensitive kinase and conformation of the mutant insulin receptor valine 382. Lebrun C., Baron V., Kaliman P., Gautier N., Dolais-Kitabgi J., Taylor S.I., Accili D., van Obberghen E.
J. Biol. Chem. 268:11272-11277(1993) · UniProtKB (1) |
| pp120/ecto-ATPase, an endogenous substrate of the insulin receptor tyrosine kinase, is expressed as two variably spliced isoforms. Najjae S.M., Accili D., Philippe N., Jernberg J., Margolis R., Taylor S.I.
J. Biol. Chem. 268:1201-1206(1993) · UniProtKB (1) |
| Substitution of Leu for Pro-193 in the insulin receptor in a patient with a genetic form of severe insulin resistance. Carrera P., Cordera R., Ferrari M., Cremonesi L., Taramelli R., Andraghetti G., Carducci C., Dozio N., Pozza G., Taylor S.I. et al.
Hum. Mol. Genet. 2:1437-1441(1993) · UniProtKB (1) |
| Substitution of glutamic acid for alanine 1135 in the putative 'catalytic loop' of the tyrosine kinase domain of the human insulin receptor. A mutation that impairs proteolytic processing into subunits and inhibits receptor tyrosine kinase activity. Cama A., de la Luz Sierra M., Quon M.J., Ottini L., Gorden P., Taylor S.I.
J. Biol. Chem. 268:8060-8069(1993) · UniProtKB (1) |
| Homozygosity for a new mutation (Ile119-->Met) in the insulin receptor gene in five sibs with familial insulin resistance. Hone J., Accili D., al-Gazali L.I., Lestringant G., Orban T., Taylor S.I.
J. Med. Genet. 31:715-716(1994) · UniProtKB (1) |
| Insulin resistance associated with decreased levels of insulin-receptor messenger ribonucleic acid: evidence of a de novo mutation in the maternal allele. Suzuki Y., Hatanaka Y., Taira M., Shimada F., Hashimoto N., Takayanagi M., Taylor S.I., Makino H., Yoshida S.
J. Clin. Endocrinol. Metab. 80:1214-1220(1995) · Mapped (12) |
| Homozygous deletion of the human insulin receptor gene results in leprechaunism. Wertheimer E., Lu S.P., Backeljauw P.F., Davenport M.L., Taylor S.I.
Nat. Genet. 5:71-73(1993) |
| Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region. Voliovitch H., Schindler D.G., Hadari Y.R., Taylor S.I., Accili D., Zick Y.
J. Biol. Chem. 270:18083-18087(1995) · Mapped (2) |
| Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. Kadowaki T., Bevins C., Cama A., Ojamaa K., Marcus-Samuels B., Kadowaki H., Beitz L., McKeon C., Taylor S.I.
Science 240:787-790(1988) · UniProtKB (1) |
