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Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes.

Levin G.P., Robinson-Cohen C., de Boer I.H., Houston D.K., Lohman K., Liu Y., Kritchevsky S.B., Cauley J.A., Tanaka T., Ferrucci L. et al.

JAMA 308:1898-1905(2012) · Mapped (6)

Target of rapamycin (TOR) controls vitellogenesis via activation of the S6 kinase in the fat body of the tick, Haemaphysalis longicornis.

Umemiya-Shirafuji R., Boldbaatar D., Liao M., Battur B., Rahman M.M., Kuboki T., Galay R.L., Tanaka T., Fujisaki K.

Int. J. Parasitol. 42:991-998(2012) · UniProtKB (1)

Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro.

Hagiya Y., Endo Y., Yonemura Y., Takahashi K., Ishizuka M., Abe F., Tanaka T., Okura I., Nakajima M., Ishikawa T. et al.

Photodiagnosis Photodyn Ther 9:204-214(2012) · Mapped (11)

SEMA4A mutations lead to susceptibility to light irradiation, oxidative stress, and ER stress in retinal pigment epithelial cells.

Tsuruma K., Nishimura Y., Kishi S., Shimazawa M., Tanaka T., Hara H.

Invest. Ophthalmol. Vis. Sci. 53:6729-6737(2012) · Mapped (10)

First-line gefitinib in patients aged 75 or older with advanced non-small cell lung cancer harboring epidermal growth factor receptor mutations: NEJ 003 study.

Maemondo M., Minegishi Y., Inoue A., Kobayashi K., Harada M., Okinaga S., Morikawa N., Oizumi S., Tanaka T., Isobe H. et al.

J Thorac Oncol 7:1417-1422(2012) · Mapped (19)

Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.

Tanaka T., Takahashi K., Yamane M., Tomida S., Nakamura S., Oshima K., Niwa A., Nishikomori R., Kambe N., Hara H. et al.

Blood 120:1299-1308(2012) · Mapped (4)

Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice.

Masuda T., Itoh K., Higashitsuji H., Higashitsuji H., Nakazawa N., Sakurai T., Liu Y., Tokuchi H., Fujita T., Zhao Y. et al.

Proc. Natl. Acad. Sci. U.S.A. 109:10885-10890(2012) · Mapped (3)

Tumor suppressor TAp73 gene specifically responds to deregulated E2F activity in human normal fibroblasts.

Ozono E., Komori H., Iwanaga R., Tanaka T., Sakae T., Kitamura H., Yamaoka S., Ohtani K.

Genes Cells 17:660-672(2012) · Mapped (4)

Circulating levels of adiponectin, leptin, fetuin-A and retinol-binding protein in patients with tuberculosis: markers of metabolism and inflammation.

Keicho N., Matsushita I., Tanaka T., Shimbo T., Hang N.T., Sakurada S., Kobayashi N., Hijikata M., Thuong P.H., Lien L.T.

PLoS ONE 7:e38703-e38703(2012) · Mapped (12)

The peptide nucleic acid-locked nucleic acid polymerase chain reaction clamp-based test for epidermal growth factor receptor mutations in bronchoscopic cytological specimens of non-small cell lung cancer.

Yamada N., Oizumi S., Asahina H., Shinagawa N., Kikuchi E., Kikuchi J., Sakakibara-Konishi J., Tanaka T., Kobayashi K., Hagiwara K. et al.

Oncology 82:341-346(2012) · Mapped (19)

Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A.

Mimura I., Nangaku M., Kanki Y., Tsutsumi S., Inoue T., Kohro T., Yamamoto S., Fujita T., Shimamura T., Suehiro J. et al.

Mol. Cell. Biol. 32:3018-3032(2012) · Mapped (16)

Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling.

Umemoto E., Otani K., Ikeno T., Verjan Garcia N., Hayasaka H., Bai Z., Jang M.H., Tanaka T., Nagasawa T., Ueda K. et al.

J. Immunol. 189:191-199(2012) · Mapped (11)

Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin.

Iwata A., Miura S., Tanaka T., Ike A., Sugihara M., Nishikawa H., Kawamura A., Saku K.

Coron. Artery Dis. 23:315-321(2012) · Mapped (1)

Hepatitis B virus e antigen physically associates with receptor-interacting serine/threonine protein kinase 2 and regulates IL-6 gene expression.

Wu S., Kanda T., Imazeki F., Nakamoto S., Tanaka T., Arai M., Roger T., Shirasawa H., Nomura F., Yokosuka O.

J. Infect. Dis. 206:415-420(2012) · Mapped (10)

Dihydrotestosterone inhibits lectin-like oxidized-LDL receptor-1 expression in aortic endothelial cells via a NF-kappaB/AP-1-mediated mechanism.

Qiu Y., Tanaka T., Nawata H., Yanase T.

Endocrinology 153:3405-3415(2012) · Mapped (11)

Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore.

Bock L.J., Pagliuca C., Kobayashi N., Grove R.A., Oku Y., Shrestha K., Alfieri C., Golfieri C., Oldani A., Dal Maschio M. et al.

Nat. Cell Biol. 14:614-624(2012)

Novel actin-like filament structure from Clostridium tetani.

Popp D., Narita A., Lee L.J., Ghoshdastider U., Xue B., Srinivasan R., Balasubramanian M.K., Tanaka T., Robinson R.C.

J. Biol. Chem. 287:21121-21129(2012) · UniProtKB (1)

Novel repressor regulates insulin sensitivity through interaction with Foxo1.

Nakae J., Cao Y., Hakuno F., Takemori H., Kawano Y., Sekioka R., Abe T., Kiyonari H., Tanaka T., Sakai J. et al.

EMBO J. 31:2275-2295(2012) · UniProtKB (5) · Mapped (13)

A genome-wide association study identifies three new risk loci for Kawasaki disease.

Japan Kawasaki Disease Genome Consortium
Onouchi Y., Ozaki K., Burns J.C., Shimizu C., Terai M., Hamada H., Honda T., Suzuki H., Suenaga T., Takeuchi T. et al.

Nat. Genet. 44:517-521(2012) · Mapped (5)

Knockdown of Sec6 improves cell-cell adhesion by increasing alpha-E-catenin in oral cancer cells.

Tanaka T., Iino M., Goto K.

FEBS Lett. 586:924-933(2012) · Mapped (13)

Kallikrein-related peptidase 8-dependent skin wound healing is associated with upregulation of kallikrein-related peptidase 6 and PAR2.

Kishibe M., Bando Y., Tanaka T., Ishida-Yamamoto A., Iizuka H., Yoshida S.

J. Invest. Dermatol. 132:1717-1724(2012) · Mapped (7)

Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.

Yoshikawa S., Kukimoto-Niino M., Parker L., Handa N., Terada T., Fujimoto T., Terazawa Y., Wakiyama M., Sato M., Sano S. et al.

Oncogene 32:27-38(2013) · Mapped (1)

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.

Okada Y., Kubo M., Ohmiya H., Takahashi A., Kumasaka N., Hosono N., Maeda S., Wen W., Dorajoo R., Go M.J. et al.

Nat. Genet. 44:302-306(2012) · Mapped (1)

Induction of mitochondrial uncoupling enhances VEGF(1)(2)(0) but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through endogenous ER stress and AMPK-related pathways.

Miyokawa-Gorin K., Takahashi K., Handa K., Kitahara A., Sumitani Y., Katsuta H., Tanaka T., Nishida S., Yoshimoto K., Ohno H. et al.

Biochem. Biophys. Res. Commun. 419:200-205(2012) · Mapped (5)

Estradiol triggers sonic-hedgehog-induced angiogenesis during peripheral nerve regeneration by downregulating hedgehog-interacting protein.

Sekiguchi H., Ii M., Jujo K., Renault M.A., Thorne T., Clarke T., Ito A., Tanaka T., Klyachko E., Tabata Y. et al.

Lab. Invest. 92:532-542(2012) · Mapped (17)

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