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Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.

Pantua H., Diao J., Ultsch M., Hazen M., Mathieu M., McCutcheon K., Takeda K., Date S., Cheung T.K., Phung Q. et al.

J. Mol. Biol. 425:1899-1914(2013) · UniProtKB (1)

Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe.

Hanazono Y., Takeda K., Oka T., Abe T., Tomonari T., Akiyama N., Aikawa Y., Yohda M., Miki K.

Structure 21:220-228(2013) · Mapped (1)

Sequential engagement of FcepsilonRI on Mast Cells and Basophil Histamine H(4) Receptor and FcepsilonRI in Allergic Rhinitis.

Shiraishi Y., Jia Y., Domenico J., Joetham A., Karasuyama H., Takeda K., Gelfand E.W.

J. Immunol. 190:539-548(2013) · Mapped (9)

Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine.

Kusu T., Kayama H., Kinoshita M., Jeon S.G., Ueda Y., Goto Y., Okumura R., Saiga H., Kurakawa T., Ikeda K. et al.

J. Immunol. 190:774-783(2013) · Mapped (1)

The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5.

Sekine Y., Hatanaka R., Watanabe T., Sono N., Iemura S., Natsume T., Kuranaga E., Miura M., Takeda K., Ichijo H.

Mol. Cell 48:692-704(2012) · Mapped (35)

Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction.

Shigekawa M., Hikita H., Kodama T., Shimizu S., Li W., Uemura A., Miyagi T., Hosui A., Kanto T., Hiramatsu N. et al.

Am. J. Pathol. 181:2105-2113(2012) · Mapped (9)

Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.

Han J., Dakhama A., Jia Y., Wang M., Zeng W., Takeda K., Shiraishi Y., Okamoto M., Ziegler S.F., Gelfand E.W.

J. Allergy Clin. Immunol. 130:1175-1186.e9(2012) · Mapped (1)

Structure of a thermophilic cyanobacterial b6f-type Rieske protein.

Veit S., Takeda K., Tsunoyama Y., Rexroth D., Rogner M., Miki K.

Acta Crystallogr. D Biol. Crystallogr. 68:1400-1408(2012) · Mapped (1)

Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins.

Qin S.Y., Hu D., Matsumoto K., Takeda K., Matsumoto N., Yamaguchi Y., Yamamoto K.

J. Biol. Chem. 287:38080-38089(2012) · Mapped (8)

Regulation of plasmacytoid dendritic cell responses by PIR-B.

Mitsuhashi Y., Nakamura A., Endo S., Takeda K., Yabe-Wada T., Nukiwa T., Takai T.

Blood 120:3256-3259(2012) · Mapped (6)

Microbial heat shock protein 65 attenuates airway hyperresponsiveness and inflammation by modulating the function of dendritic cells.

Shin Y.S., Takeda K., Shiraishi Y., Jeong Y.Y., Domenico J., Jia Y., Han J., Spallek R., Singh M., Lucas J.J. et al.

J. Immunol. 189:3404-3410(2012) · Mapped (10)

Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.

Sekine S., Kanamaru Y., Koike M., Nishihara A., Okada M., Kinoshita H., Kamiyama M., Maruyama J., Uchiyama Y., Ishihara N. et al.

J. Biol. Chem. 287:34635-34645(2012) · Mapped (1)

Coordinated expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 and heme oxygenase 2: evidence for a regulatory link between glycolysis and heme catabolism.

Li B., Takeda K., Ishikawa K., Yoshizawa M., Sato M., Shibahara S., Furuyama K.

Tohoku J. Exp. Med. 228:27-41(2012) · Mapped (8)

Dietary folic acid promotes survival of Foxp3+ regulatory T cells in the colon.

Kinoshita M., Kayama H., Kusu T., Yamaguchi T., Kunisawa J., Kiyono H., Sakaguchi S., Takeda K.

J. Immunol. 189:2869-2878(2012) · Mapped (2)

A cluster of interferon-gamma-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.

Yamamoto M., Okuyama M., Ma J.S., Kimura T., Kamiyama N., Saiga H., Ohshima J., Sasai M., Kayama H., Okamoto T. et al.

Immunity 37:302-313(2012) · Mapped (4)

Critical role of AIM2 in Mycobacterium tuberculosis infection.

Saiga H., Kitada S., Shimada Y., Kamiyama N., Okuyama M., Makino M., Yamamoto M., Takeda K.

Int. Immunol. 24:637-644(2012) · Mapped (4)

Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon.

Jeon S.G., Kayama H., Ueda Y., Takahashi T., Asahara T., Tsuji H., Tsuji N.M., Kiyono H., Ma J.S., Kusu T. et al.

PLoS Pathog. 8:e1002714-e1002714(2012) · Mapped (2)

Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0.

Hanazono Y., Takeda K., Yohda M., Miki K.

J. Mol. Biol. 422:100-108(2012) · UniProtKB (1)

Impaired development of melanoblasts in the black-eyed white Mitf(mi-bw) mouse, a model for auditory-pigmentary disorders.

Hozumi H., Takeda K., Yoshida-Amano Y., Takemoto Y., Kusumi R., Fukuzaki-Dohi U., Higashitani A., Yamamoto H., Shibahara S.

Genes Cells 17:494-508(2012) · Mapped (8)

Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.

Joetham A., Ohnishi H., Okamoto M., Takeda K., Schedel M., Domenico J., Dakhama A., Gelfand E.W.

J. Biol. Chem. 287:17100-17108(2012) · Mapped (14)

Intestinal CX3C chemokine receptor 1(high) (CX3CR1(high)) myeloid cells prevent T-cell-dependent colitis.

Kayama H., Ueda Y., Sawa Y., Jeon S.G., Ma J.S., Okumura R., Kubo A., Ishii M., Okazaki T., Murakami M. et al.

Proc. Natl. Acad. Sci. U.S.A. 109:5010-5015(2012) · Mapped (13)

Identification and characterization of a GDSL lipase-like protein that catalyzes the ester-forming reaction for pyrethrin biosynthesis in Tanacetum cinerariifolium- a new target for plant protection.

Kikuta Y., Ueda H., Takahashi M., Mitsumori T., Yamada G., Sakamori K., Takeda K., Furutani S., Nakayama K., Katsuda Y. et al.

Plant J. 71:183-193(2012) · UniProtKB (4)

Acetylcholinesterase inhibitors attenuate angiogenesis.

Miyazaki R., Ichiki T., Hashimoto T., Ikeda J., Kamiharaguchi A., Narabayashi E., Matsuura H., Takeda K., Sunagawa K.

Clin. Sci. 123:241-249(2012) · Mapped (2)

Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster.

Ishida Y., Sekine Y., Oguchi H., Chihara T., Miura M., Ichijo H., Takeda K.

PLoS ONE 7:e30265-e30265(2012) · Mapped (10)

Lipocalin-type prostaglandin D synthase as a marker for the proliferative potential of melanocyte-lineage cells in the human skin.

Shimanuki M., Takeda K., Kawaguchi M., Suzuki T., Shibahara S.

J. Dermatol. 39:699-704(2012) · Mapped (1)

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