| Immune suppression and resistance mediated by constitutive activation of Wnt/beta-catenin signaling in human melanoma cells. Yaguchi T., Goto Y., Kido K., Mochimaru H., Sakurai T., Tsukamoto N., Kudo-Saito C., Fujita T., Sumimoto H., Kawakami Y.
J. Immunol. 189:2110-2117(2012) · Mapped (6) |
| Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression. Yasuda T., Saegusa C., Kamakura S., Sumimoto H., Fukuda M.
Mol. Biol. Cell 23:3229-3239(2012) · Mapped (6) |
| Expression and subcellular localization of mammalian formin Fhod3 in the embryonic and adult heart. Kan-o M., Takeya R., Taniguchi K., Tanoue Y., Tominaga R., Sumimoto H.
PLoS ONE 7:e34765-e34765(2012) · Mapped (2) |
| Atypical membrane-embedded phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2)-binding site on p47(phox) Phox homology (PX) domain revealed by NMR. Stampoulis P., Ueda T., Matsumoto M., Terasawa H., Miyano K., Sumimoto H., Shimada I.
J. Biol. Chem. 287:17848-17859(2012) · Mapped (2) |
| Noxa1 as a moderate activator of Nox2-based NADPH oxidase. Kawano M., Miyamoto K., Kaito Y., Sumimoto H., Tamura M.
Arch. Biochem. Biophys. 519:1-7(2012) · Mapped (1) |
| Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN). Yuzawa S., Kamakura S., Iwakiri Y., Hayase J., Sumimoto H.
Proc. Natl. Acad. Sci. U.S.A. 108:19210-19215(2011) · Mapped (17) |
| Enhanced cancer immunotherapy using STAT3-depleted dendritic cells with high Th1-inducing ability and resistance to cancer cell-derived inhibitory factors. Iwata-Kajihara T., Sumimoto H., Kawamura N., Ueda R., Takahashi T., Mizuguchi H., Miyagishi M., Takeda K., Kawakami Y.
J. Immunol. 187:27-36(2011) · Mapped (14) |
| Polarity proteins Bem1 and Cdc24 are components of the filamentous fungal NADPH oxidase complex. Takemoto D., Kamakura S., Saikia S., Becker Y., Wrenn R., Tanaka A., Sumimoto H., Scott B.
Proc. Natl. Acad. Sci. U.S.A. 108:2861-2866(2011) · UniProtKB (2) |
| A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase. Maehara Y., Miyano K., Yuzawa S., Akimoto R., Takeya R., Sumimoto H.
J. Biol. Chem. 285:31435-31445(2010) · Mapped (5) |
| The domain organization of p67 phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes. Yuzawa S., Miyano K., Honbou K., Inagaki F., Sumimoto H.
J Innate Immun 1:543-555(2009) · Mapped (5) |
| Mammalian formin fhod3 regulates actin assembly and sarcomere organization in striated muscles. Taniguchi K., Takeya R., Suetsugu S., Kan-O M., Narusawa M., Shiose A., Tominaga R., Sumimoto H.
J. Biol. Chem. 284:29873-29881(2009) · Mapped (4) |
| Simultaneous suppression of MITF and BRAF V600E enhanced inhibition of melanoma cell proliferation. Kido K., Sumimoto H., Asada S., Okada S.M., Yaguchi T., Kawamura N., Miyagishi M., Saida T., Kawakami Y.
Cancer Sci. 100:1863-1869(2009) · Mapped (10) |
| NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae. Ogura K., Tandai T., Yoshinaga S., Kobashigawa Y., Kumeta H., Ito T., Sumimoto H., Inagaki F.
J. Biochem. 146:317-325(2009) · Mapped (2) |
| Role for the first SH3 domain of p67phox in activation of superoxide-producing NADPH oxidases. Maehara Y., Miyano K., Sumimoto H.
Biochem. Biophys. Res. Commun. 379:589-593(2009) · Mapped (9) |
| Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival. Shono T., Yokoyama N., Uesaka T., Kuroda J., Takeya R., Yamasaki T., Amano T., Mizoguchi M., Suzuki S.O., Niiro H. et al.
Int. J. Cancer 123:787-792(2008) · Mapped (6) |
| The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells. Takeya R., Taniguchi K., Narumiya S., Sumimoto H.
EMBO J. 27:618-628(2008) · Mapped (4) |
| Structure and function of the PB1 domain, a protein interaction module conserved in animals, fungi, amoebas, and plants. Sumimoto H., Kamakura S., Ito T.
Sci. STKE 2007:re6-re6(2007) · Mapped (2) |
| Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding. Honbou K., Minakami R., Yuzawa S., Takeya R., Suzuki N.N., Kamakura S., Sumimoto H., Inagaki F.
EMBO J. 26:1176-1186(2007) · UniProtKB (2) |
| Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1). Yamamoto A., Kami K., Takeya R., Sumimoto H.
Biochem. Biophys. Res. Commun. 352:560-565(2007) · UniProtKB (2) · Mapped (1) |
| Expression and function of Noxo1gamma, an alternative splicing form of the NADPH oxidase organizer 1. Takeya R., Taura M., Yamasaki T., Naito S., Sumimoto H.
FEBS J. 273:3663-3677(2006) · Mapped (2) |
| Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. Miyano K., Ueno N., Takeya R., Sumimoto H.
J. Biol. Chem. 281:21857-21868(2006) · UniProtKB (1) |
| Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox. Nobuhisa I., Takeya R., Ogura K., Ueno N., Kohda D., Inagaki F., Sumimoto H.
Biochem. J. 396:183-192(2006) · Mapped (6) |
| Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3. Izaki T., Kamakura S., Kohjima M., Sumimoto H.
Biochem. Biophys. Res. Commun. 341:1001-1006(2006) · UniProtKB (5) |
| NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide. Ogura K., Nobuhisa I., Yuzawa S., Takeya R., Torikai S., Saikawa K., Sumimoto H., Inagaki F.
J. Biol. Chem. 281:3660-3668(2006) · Mapped (4) |
| The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells. Kuroda J., Nakagawa K., Yamasaki T., Nakamura K., Takeya R., Kuribayashi F., Imajoh-Ohmi S., Igarashi K., Shibata Y., Sueishi K. et al.
Genes Cells 10:1139-1151(2005) · UniProtKB (1) · Mapped (5) |
