| Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the Sult1e1 gene in mouse liver. Sueyoshi T., Green W.D., Vinal K., Woodrum T.S., Moore R., Negishi M.
PLoS ONE 6:e21229-e21229(2011) · Mapped (4) |
| Midkine expression is correlated with an adverse prognosis and is down-regulated by p53 in oral squamous cell carcinoma. Ota K., Fujimori H., Ueda M., Jono H., Shinriki S., Ota T., Sueyoshi T., Taura M., Taguma A., Kai H. et al.
Int. J. Oncol. 37:797-804(2010) · Mapped (36) |
| Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3). Mutoh S., Osabe M., Inoue K., Moore R., Pedersen L., Perera L., Rebolloso Y., Sueyoshi T., Negishi M.
J. Biol. Chem. 284:34785-34792(2009) · UniProtKB (1) · Mapped (30) |
| PPP1R16A, the membrane subunit of protein phosphatase 1beta, signals nuclear translocation of the nuclear receptor constitutive active/androstane receptor. Sueyoshi T., Moore R., Sugatani J., Matsumura Y., Negishi M.
Mol. Pharmacol. 73:1113-1121(2008) · Mapped (27) |
| Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver. Nakamura K., Moore R., Negishi M., Sueyoshi T.
J. Biol. Chem. 282:9768-9776(2007) · Mapped (3) |
| Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor. Sugatani J., Sueyoshi T., Negishi M., Miwa M.
Meth. Enzymol. 400:92-104(2005) · Mapped (15) |
| Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1. Sugatani J., Nishitani S., Yamakawa K., Yoshinari K., Sueyoshi T., Negishi M., Miwa M.
Mol. Pharmacol. 67:845-855(2005) · Mapped (31) |
| Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver. Squires E.J., Sueyoshi T., Negishi M.
J. Biol. Chem. 279:49307-49314(2004) · Mapped (7) |
| Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells. Kobayashi K., Sueyoshi T., Inoue K., Moore R., Negishi M.
Mol. Pharmacol. 64:1069-1075(2003) · UniProtKB (4) |
| A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression. Wang H., Faucette S., Sueyoshi T., Moore R., Ferguson S., Negishi M., LeCluyse E.L.
J. Biol. Chem. 278:14146-14152(2003) · Mapped (5) |
| Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia. Sugatani J., Yamakawa K., Yoshinari K., Machida T., Takagi H., Mori M., Kakizaki S., Sueyoshi T., Negishi M., Miwa M.
Biochem. Biophys. Res. Commun. 292:492-497(2002) · Mapped (15) |
| Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. Ueda A., Hamadeh H.K., Webb H.K., Yamamoto Y., Sueyoshi T., Afshari C.A., Lehmann J.M., Negishi M.
Mol. Pharmacol. 61:1-6(2002) · Mapped (4) |
| Nuclear receptor CAR as a regulatory factor for the sexually dimorphic induction of CYB2B1 gene by phenobarbital in rat livers. Yoshinari K., Sueyoshi T., Moore R., Negishi M.
Mol. Pharmacol. 59:278-284(2001) · UniProtKB (1) · Mapped (2) |
| Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/N-sulfotransferase 1. Kakuta Y., Sueyoshi T., Negishi M., Pedersen L.C.
J. Biol. Chem. 274:10673-10676(1999) · UniProtKB (1) |
| The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. Sueyoshi T., Kawamoto T., Zelko I., Honkakoski P., Negishi M.
J. Biol. Chem. 274:6043-6046(1999) · UniProtKB (1) |
| A role of Lys614 in the sulfotransferase activity of human heparan sulfate N-deacetylase/N-sulfotransferase. Sueyoshi T., Kakuta Y., Pedersen L.C., Wall F.E., Pedersen L.G., Negishi M.
FEBS Lett. 433:211-214(1998) · UniProtKB (1) |
| A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver. Sueyoshi T., Kobayashi R., Nishio K., Aida K., Moore R., Wada T., Handa H., Negishi M.
Mol. Cell. Biol. 15:4158-4166(1995) · UniProtKB (3) · Mapped (5) |
| A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP. Yokomori N., Kobayashi R., Moore R., Sueyoshi T., Negishi M.
Mol. Cell. Biol. 15:5355-5362(1995) · Mapped (3) |
| Bovine high molecular weight kininogen. The amino acid sequence, positions of carbohydrate chains and disulfide bridges in the heavy chain portion. Sueyoshi T., Miyata T., Hashimoto N., Kato H., Hayashida H., Miyata T., Iwanaga S.
J. Biol. Chem. 262:2768-2779(1987) · UniProtKB (2) |
| A new trisaccharide sugar chain linked to a serine residue in bovine blood coagulation factors VII and IX. Hase S., Kawabata S., Nishimura H., Takeya H., Sueyoshi T., Miyata T., Iwanaga S., Takao T., Shimonishi Y., Ikenaka T.
J. Biochem. 104:867-868(1988) · UniProtKB (2) |
| Ornitho-kininogen and ornitho-kinin: isolation, characterization and chemical structure. Kimura M., Sueyoshi T., Morita T., Tanaka K., Iwanaga S.
Adv. Exp. Med. Biol. 247A:359-367(1989) · UniProtKB (2) |
| Cysteine proteinase inhibitor in the ascitic fluid of sarcoma 180 tumor-bearing mice is a low molecular weight kininogen. Partial NH2- and COOH-terminal sequences and susceptibility to various glandular kallikreins. Sueyoshi T., Uwani M., Itoh N., Okamoto H., Muta T., Tokunaga F., Takada K., Iwanaga S.
J. Biol. Chem. 265:10030-10035(1990) · UniProtKB (1) |
