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Probing the relationship between insulin sensitivity and longevity using genetically modified mice.

Nelson J.F., Strong R., Bokov A., Diaz V., Ward W.

J. Gerontol. A Biol. Sci. Med. Sci. 67:1332-1338(2012) · Mapped (10)

Increased phylogenetic diversity of bovine viral diarrhoea virus type 1 isolates in England and Wales since 2001.

Strong R., Errington J., Cook R., Ross-Smith N., Wakeley P., Steinbach F.

Vet. Microbiol. 162:315-320(2013) · UniProtKB (19)

Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines.

Correnti C., Richardson V., Sia A.K., Bandaranayake A.D., Ruiz M., Suryo Rahmanto Y., Kovacevic Z., Clifton M.C., Holmes M.A., Kaiser B.K. et al.

PLoS ONE 7:e43696-e43696(2012) · Mapped (2)

Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.

Ramos F.J., Chen S.C., Garelick M.G., Dai D.F., Liao C.Y., Schreiber K.H., MacKay V.L., An E.H., Strong R., Ladiges W.C. et al.

Sci Transl Med 4:144ra103-144ra103(2012) · Mapped (8)

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice.

Halloran J., Hussong S.A., Burbank R., Podlutskaya N., Fischer K.E., Sloane L.B., Austad S.N., Strong R., Richardson A., Hart M.J. et al.

Neuroscience 223:102-113(2012) · Mapped (2)

Galline Ex-FABP is an antibacterial siderocalin and a lysophosphatidic acid sensor functioning through dual ligand specificities.

Correnti C., Clifton M.C., Abergel R.J., Allred B., Hoette T.M., Ruiz M., Cancedda R., Raymond K.N., Descalzi F., Strong R.K.

Structure 19:1796-1806(2011) · UniProtKB (1)

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.

Azoitei M.L., Correia B.E., Ban Y.E., Carrico C., Kalyuzhniy O., Chen L., Schroeter A., Huang P.S., McLellan J.S., Kwong P.D. et al.

Science 334:373-376(2011) · Mapped (1)

Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors.

Bandaranayake A.D., Correnti C., Ryu B.Y., Brault M., Strong R.K., Rawlings D.J.

Nucleic Acids Res. 39:E143-E143(2011) · UniProtKB (1)

Crystal structure of a gammadelta T-cell receptor specific for the human MHC class I homolog MICA.

Xu B., Pizarro J.C., Holmes M.A., McBeth C., Groh V., Spies T., Strong R.K.

Proc. Natl. Acad. Sci. U.S.A. 108:2414-2419(2011) · Mapped (49)

The structural basis of 5' triphosphate double-stranded RNA recognition by RIG-I C-terminal domain.

Lu C., Xu H., Ranjith-Kumar C.T., Brooks M.T., Hou T.Y., Hu F., Herr A.B., Strong R.K., Kao C.C., Li P.

Structure 18:1032-1043(2010) · Mapped (1)

Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.

Bao G., Clifton M., Hoette T.M., Mori K., Deng S.X., Qiu A., Viltard M., Williams D., Paragas N., Leete T. et al.

Nat. Chem. Biol. 6:602-609(2010) · Mapped (1)

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.

Caccamo A., Majumder S., Richardson A., Strong R., Oddo S.

J. Biol. Chem. 285:13107-13120(2010) · Mapped (12)

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5.

Li X., Lu C., Stewart M., Xu H., Strong R.K., Igumenova T., Li P.

Arch. Biochem. Biophys. 488:23-33(2009) · UniProtKB (1) · Mapped (3)

Neuronal PPARgamma deficiency increases susceptibility to brain damage after cerebral ischemia.

Zhao X., Strong R., Zhang J., Sun G., Tsien J.Z., Cui Z., Grotta J.C., Aronowski J.

J. Neurosci. 29:6186-6195(2009) · Mapped (10)

Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.

Chan Y.R., Liu J.S., Pociask D.A., Zheng M., Mietzner T.A., Berger T., Mak T.W., Clifton M.C., Strong R.K., Ray P. et al.

J. Immunol. 182:4947-4956(2009) · Mapped (28)

Lipocalin 2 promotes breast cancer progression.

Yang J., Bielenberg D.R., Rodig S.J., Doiron R., Clifton M.C., Kung A.L., Strong R.K., Zurakowski D., Moses M.A.

Proc. Natl. Acad. Sci. U.S.A. 106:3913-3918(2009) · Mapped (2)

The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport.

Abergel R.J., Clifton M.C., Pizarro J.C., Warner J.A., Shuh D.K., Strong R.K., Raymond K.N.

J. Am. Chem. Soc. 130:11524-11534(2008) · Mapped (1)

Lipocalin 2 is required for BCR-ABL-induced tumorigenesis.

Leng X., Lin H., Ding T., Wang Y., Wu Y., Klumpp S., Sun T., Zhou Y., Monaco P., Belmont J. et al.

Oncogene 27:6110-6119(2008) · Mapped (2)

Structural basis for NKG2A/CD94 recognition of HLA-E.

Kaiser B.K., Pizarro J.C., Kerns J., Strong R.K.

Proc. Natl. Acad. Sci. U.S.A. 105:6696-6701(2008) · UniProtKB (2) · Mapped (29)

A new twist in TCR diversity revealed by a forbidden alphabeta TCR.

McBeth C., Seamons A., Pizarro J.C., Fleishman S.J., Baker D., Kortemme T., Goverman J.M., Strong R.K.

J. Mol. Biol. 375:1306-1319(2008) · UniProtKB (1) · Mapped (2)

Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage.

Zhao X., Sun G., Zhang J., Strong R., Dash P.K., Kan Y.W., Grotta J.C., Aronowski J.

Stroke 38:3280-3286(2007) · Mapped (2)

Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands.

Kaiser B.K., Yim D., Chow I.-T., Gonzalez S., Dai Z., Mann H.H., Strong R.K., Groh V., Spies T.

Nature 447:482-486(2007) · UniProtKB (2) · Mapped (51)

Selection for functional diversity drives accumulation of point mutations in Dr adhesins of Escherichia coli.

Korotkova N., Chattopadhyay S., Tabata T.A., Beskhlebnaya V., Vigdorovich V., Kaiser B.K., Strong R.K., Dykhuizen D.E., Sokurenko E.V., Moseley S.L.

Mol. Microbiol. 64:180-194(2007) · UniProtKB (48)

A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin.

Andersen-Nissen E., Smith K.D., Bonneau R., Strong R.K., Aderem A.

J. Exp. Med. 204:393-403(2007) · Mapped (6)

Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression.

Zhao X., Zhang Y., Strong R., Zhang J., Grotta J.C., Aronowski J.

J. Neurochem. 101:652-663(2007) · Mapped (6)

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