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Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.

El Omari K., Dhaliwal B., Ren J., Abrescia N.G., Lockyer M., Powell K.L., Hawkins A.R., Stammers D.K.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67:1179-1183(2011) · UniProtKB (1) · Mapped (1)

Crystallographic and microcalorimetric analyses reveal the structural basis for high arginine specificity in the Salmonella enterica serovar Typhimurium periplasmic binding protein STM4351.

Stamp A.L., Owen P., El Omari K., Lockyer M., Lamb H.K., Charles I.G., Hawkins A.R., Stammers D.K.

Proteins 79:2352-2357(2011) · UniProtKB (1)

Structural and functional characterization of Salmonella enterica serovar Typhimurium YcbL: an unusual Type II glyoxalase.

Stamp A.L., Owen P., El Omari K., Nichols C.E., Lockyer M., Lamb H.K., Charles I.G., Hawkins A.R., Stammers D.K.

Protein Sci. 19:1897-1905(2010) · UniProtKB (1)

Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.

Bird L.E., Ren J., Nettleship J.E., Folkers G.E., Owens R.J., Stammers D.K.

BMC Struct. Biol. 10:13-13(2010) · UniProtKB (2)

The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension.

Wienk H., Lammers I., Hotze A., Wu J., Wechselberger R.W., Owens R., Stammers D.K., Stuart D., Kaptein R., Folkers G.E.

Biochemistry 48:4431-4439(2009) · UniProtKB (1) · Mapped (1)

The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis.

Nichols C.E., Sainsbury S., Ren J., Walter T.S., Verma A., Stammers D.K., Saunders N.J., Owens R.J.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65:204-209(2009) · UniProtKB (1)

Dinucleotide-sensing proteins: linking signaling networks and regulating transcription.

Lamb H.K., Stammers D.K., Hawkins A.R.

Sci Signal 1:pe38-pe38(2008) · Mapped (1)

Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors.

Ren J., Chamberlain P.P., Stamp A., Short S.A., Weaver K.L., Romines K.R., Hazen R., Freeman A., Ferris R.G., Andrews C.W. et al.

J. Med. Chem. 51:5000-5008(2008) · Mapped (1)

Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA.

Kotaka M., Johnson C., Lamb H.K., Hawkins A.R., Ren J., Stammers D.K.

J. Mol. Biol. 381:373-382(2008) · UniProtKB (2)

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.

Szumska D., Pieles G., Essalmani R., Bilski M., Mesnard D., Kaur K., Franklyn A., El Omari K., Jefferis J., Bentham J. et al.

Genes Dev. 22:1465-1477(2008) · Mapped (23)

Structure of the ribosomal interacting GTPase YjeQ from the enterobacterial species Salmonella typhimurium.

Nichols C.E., Johnson C., Lamb H.K., Lockyer M., Charles I.G., Hawkins A.R., Stammers D.K.

Acta Crystallogr. F 63:922-928(2007) · UniProtKB (1)

Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium.

Lamb H.K., Thompson P., Elliott C., Charles I.G., Richards J., Lockyer M., Watkins N., Nichols C., Stammers D.K., Bagshaw C.R. et al.

Protein Sci. 16:2391-2402(2007) · UniProtKB (5)

Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.

Cader M.Z., Ren J., James P.A., Bird L.E., Talbot K., Stammers D.K.

FEBS Lett. 581:2959-2964(2007) · UniProtKB (1) · Mapped (1)

Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases.

Ren J., Nichols C.E., Chamberlain P.P., Weaver K.L., Short S.A., Chan J.H., Kleim J.P., Stammers D.K.

J. Med. Chem. 50:2301-2309(2007) · Mapped (1)

Characterization of Salmonella typhimurium yegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases.

Nichols C.E., Lamb H.K., Lockyer M., Charles I.G., Pyne S., Hawkins A.R., Stammers D.K.

Proteins 68:13-25(2007) · UniProtKB (1)

The structure and transcriptional analysis of a global regulator from Neisseria meningitidis.

Ren J., Sainsbury S., Combs S.E., Capper R.G., Jordan P.W., Berrow N.S., Stammers D.K., Saunders N.J., Owens R.J.

J. Biol. Chem. 282:14655-14664(2007) · UniProtKB (1)

Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design.

El Omari K., Solaroli N., Karlsson A., Balzarini J., Stammers D.K.

BMC Struct. Biol. 6:22-22(2006) · UniProtKB (1)

Calcium regulation of chloroplast protein translocation is mediated by calmodulin binding to Tic32.

Chigri F., Hoermann F., Stamp A., Stammers D.K., Boelter B., Soll J., Vothknecht U.C.

Proc. Natl. Acad. Sci. U.S.A. 103:16051-16056(2006) · UniProtKB (2)

Structure of Staphylococcus aureus guanylate monophosphate kinase.

El Omari K., Dhaliwal B., Lockyer M., Charles I., Hawkins A.R., Stammers D.K.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62:949-953(2006) · Mapped (1)

Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.

Ren J., Nichols C.E., Stamp A., Chamberlain P.P., Ferris R., Weaver K.L., Short S.A., Stammers D.K.

FEBS J. 273:3850-3860(2006) · Mapped (2)

Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine.

Kotaka M., Ren J., Lockyer M., Hawkins A.R., Stammers D.K.

J. Biol. Chem. 281:31544-31552(2006) · UniProtKB (1)

Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate.

Dhaliwal B., Ren J., Lockyer M., Charles I., Hawkins A.R., Stammers D.K.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62:710-715(2006) · Mapped (1)

Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implications for drug design.

El Omari K., Bronckaers A., Liekens S., Perez-Perez M.J., Balzarini J., Stammers D.K.

Biochem. J. 399:199-204(2006) · UniProtKB (1) · Mapped (4)

Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution.

Nichols C.E., Sainsbury S., Berrow N.S., Alderton D., Saunders N.J., Stammers D.K., Owens R.J.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62:494-497(2006) · UniProtKB (1)

Structural characterization of Salmonella typhimurium YeaZ, an M22 O-sialoglycoprotein endopeptidase homolog.

Nichols C.E., Johnson C., Lockyer M., Charles I.G., Lamb H.K., Hawkins A.R., Stammers D.K.

Proteins 64:111-123(2006) · UniProtKB (1)

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