| Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injury. Gadepalli R., Singh N.K., Kundumani-Sridharan V., Heckle M.R., Rao G.N.
Arterioscler. Thromb. Vasc. Biol. 32:2652-2661(2012) · Mapped (3) |
| Protein kinase N1 is a novel substrate of NFATc1-mediated cyclin D1-CDK6 activity and modulates vascular smooth muscle cell division and migration leading to inward blood vessel wall remodeling. Singh N.K., Kundumani-Sridharan V., Kumar S., Verma S.K., Kotla S., Mukai H., Heckle M.R., Rao G.N.
J. Biol. Chem. 287:36291-36304(2012) · Mapped (13) |
| Novel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phase influencing cell migration and second phase directing cell proliferation. Kundumani-Sridharan V., Van Quyen D., Subramani J., Singh N.K., Chin Y.E., Rao G.N.
J. Biol. Chem. 287:22463-22482(2012) · Mapped (4) |
| 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation. Singh N.K., Kundumani-Sridharan V., Rao G.N.
Blood 118:5701-5712(2011) · Mapped (8) |
| Activation of cytosolic phospholipase A2 downstream of the Src-phospholipase D1 (PLD1)-protein kinase C gamma (PKCgamma) signaling axis is required for hypoxia-induced pathological retinal angiogenesis. Zhang Q., Wang D., Singh N.K., Kundumani-Sridharan V., Gadiparthi L., Rao C.h.M., Rao G.N.
J. Biol. Chem. 286:22489-22498(2011) · Mapped (22) |
| Drosophila polypyrimidine tract-binding protein is necessary for spermatid individualization. Robida M., Sridharan V., Morgan S., Rao T., Singh R.
Proc. Natl. Acad. Sci. U.S.A. 107:12570-12575(2010) · Mapped (10) |
| AP-1 (Fra-1/c-Jun)-mediated induction of expression of matrix metalloproteinase-2 is required for 15S-hydroxyeicosatetraenoic acid-induced angiogenesis. Singh N.K., Quyen D.V., Kundumani-Sridharan V., Brooks P.C., Rao G.N.
J. Biol. Chem. 285:16830-16843(2010) · Mapped (19) |
| 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression. Kundumani-Sridharan V., Niu J., Wang D., Van Quyen D., Zhang Q., Singh N.K., Subramani J., Karri S., Rao G.N.
Blood 115:2105-2116(2010) · Mapped (9) |
| Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration. Potula H.S., Wang D., Quyen D.V., Singh N.K., Kundumani-Sridharan V., Karpurapu M., Park E.A., Glasgow W.C., Rao G.N.
J. Biol. Chem. 284:31142-31155(2009) · Mapped (3) |
| Plasma membrane nucleolin is a receptor for the anticancer aptamer AS1411 in MV4-11 leukemia cells. Soundararajan S., Wang L., Sridharan V., Chen W., Courtenay-Luck N., Jones D., Spicer E.K., Fernandes D.J.
Mol. Pharmacol. 76:984-991(2009) · Mapped (5) |
| The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8. Cheranov S.Y., Wang D., Kundumani-Sridharan V., Karpurapu M., Zhang Q., Chava K.R., Rao G.N.
Blood 113:6023-6033(2009) · Mapped (10) |
| VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase. Wright G.L., Maroulakou I.G., Eldridge J., Liby T.L., Sridharan V., Tsichlis P.N., Muise-Helmericks R.C.
FASEB J. 22:3264-3275(2008) · UniProtKB (2) · Mapped (2) |
| An essential role for gp130 in neointima formation following arterial injury. Wang D., Liu Z., Li Q., Karpurapu M., Kundumani-Sridharan V., Cao H., Dronadula N., Rizvi F., Bajpai A.K., Zhang C. et al.
Circ. Res. 100:807-816(2007) · Mapped (3) |
| Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid. Trivedi O.A., Arora P., Vats A., Ansari M.Z., Tickoo R., Sridharan V., Mohanty D., Gokhale R.S.
Mol. Cell 17:631-643(2005) · UniProtKB (1) |
| Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria. Trivedi O.A., Arora P., Sridharan V., Tickoo R., Mohanty D., Gokhale R.S.
Nature 428:441-445(2004) · UniProtKB (8) |