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1 - 25 of 84 results for author:"Springer T.A."Drop in Literature Citations

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Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor.

Zhang X., Halvorsen K., Zhang C.Z., Wong W.P., Springer T.A.

Science 324:1330-1334(2009) · Mapped (6)

Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor.

Zhang Q., Zhou Y.F., Zhang C.Z., Zhang X., Lu C., Springer T.A.

Proc. Natl. Acad. Sci. U.S.A. 106:9226-9231(2009) · Mapped (6)

The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.

Vanhoorelbeke K., De Meyer S.F., Pareyn I., Melchior C., Plancon S., Margue C., Pradier O., Fondu P., Kieffer N., Springer T.A. et al.

J. Biol. Chem. 284:14914-14920(2009) · Mapped (10)

Rationally designed integrin beta3 mutants stabilized in the high affinity conformation.

Luo B.H., Karanicolas J., Harmacek L.D., Baker D., Springer T.A.

J. Biol. Chem. 284:3917-3924(2009) · Mapped (4)

Functional and structural stability of the epidermal growth factor receptor in detergent micelles and phospholipid nanodiscs.

Mi L.Z., Grey M.J., Nishida N., Walz T., Lu C., Springer T.A.

Biochemistry 47:10314-10323(2008) · Mapped (15)

Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3.

Springer T.A., Zhu J., Xiao T.

J. Cell Biol. 182:791-800(2008) · Mapped (1)

An unusual allosteric mobility of the C-terminal helix of a high-affinity alphaL integrin I domain variant bound to ICAM-5.

Zhang H., Casasnovas J.M., Jin M., Liu J.H., Gahmberg C.G., Springer T.A., Wang J.H.

Mol. Cell 31:432-437(2008) · Mapped (1)

Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration.

Morin N.A., Oakes P.W., Hyun Y.M., Lee D., Chin Y.E., Chin E.Y., King M.R., Springer T.A., Shimaoka M., Tang J.X. et al.

J. Exp. Med. 205:195-205(2008) · Mapped (16)

Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization.

Chen X., Kim T.D., Carman C.V., Mi L.Z., Song G., Springer T.A.

Proc. Natl. Acad. Sci. U.S.A. 104:15358-15363(2007) · Mapped (3)

Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots.

Bonasio R., Carman C.V., Kim E., Sage P.T., Love K.R., Mempel T.R., Springer T.A., von Andrian U.H.

Proc. Natl. Acad. Sci. U.S.A. 104:14753-14758(2007) · Mapped (15)

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling.

Zhu J., Carman C.V., Kim M., Shimaoka M., Springer T.A., Luo B.H.

Blood 110:2475-2483(2007) · Mapped (10)

Activation of leukocyte beta2 integrins by conversion from bent to extended conformations.

Nishida N., Xie C., Shimaoka M., Cheng Y., Walz T., Springer T.A.

Immunity 25:583-594(2006) · Mapped (10)

A high affinity human antibody antagonist of P-selectin mediated rolling.

Swers J.S., Widom A., Phan U., Springer T.A., Wittrup K.D.

Biochem. Biophys. Res. Commun. 350:508-513(2006) · Mapped (12)

AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes.

Shimaoka M., Kim M., Cohen E.H., Yang W., Astrof N., Peer D., Salas A., Ferrand A., Springer T.A.

Proc. Natl. Acad. Sci. U.S.A. 103:13991-13996(2006) · Mapped (5)

Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2.

Chen J., Yang W., Kim M., Carman C.V., Springer T.A.

Proc. Natl. Acad. Sci. U.S.A. 103:13062-13067(2006) · Mapped (5)

Transition from rolling to firm adhesion can be mimicked by extension of integrin alphaLbeta2 in an intermediate affinity state.

Salas A., Shimaoka M., Phan U., Kim M., Springer T.A.

J. Biol. Chem. 281:10876-10882(2006) · Mapped (11)

An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.

Song G., Yang Y., Liu J.-H., Casasnovas J.M., Shimaoka M., Springer T.A., Wang J.-H.

Proc. Natl. Acad. Sci. U.S.A. 102:3366-3371(2005) · UniProtKB (1) · Mapped (1)

Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2.

Vorup-Jensen T., Carman C.V., Shimaoka M., Schuck P., Svitel J., Springer T.A.

Proc. Natl. Acad. Sci. U.S.A. 102:1614-1619(2005) · Mapped (11)

The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.

Kim M., Carman C.V., Yang W., Salas A., Springer T.A.

J. Cell Biol. 167:1241-1253(2004) · Mapped (14)

Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs).

Jimenez D., Roda-Navarro P., Springer T.A., Casasnovas J.M.

J. Biol. Chem. 280:5854-5861(2005) · Mapped (5)

RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.

Lafuente E.M., van Puijenbroek A.A., Krause M., Carman C.V., Freeman G.J., Berezovskaya A., Constantine E., Springer T.A., Gertler F.B., Boussiotis V.A.

Dev. Cell 7:585-595(2004) · UniProtKB (2)

The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

Chen J., Takagi J., Xie C., Xiao T., Luo B.H., Springer T.A.

J. Biol. Chem. 279:55556-55561(2004) · Mapped (11)

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics.

Xiao T., Takagi J., Coller B.S., Wang J.H., Springer T.A.

Nature 432:59-67(2004) · Mapped (2)

Structural basis for dimerization of ICAM-1 on the cell surface.

Yang Y., Jun C.D., Liu J.H., Zhang R., Joachimiak A., Springer T.A., Wang J.H.

Mol. Cell 14:269-276(2004) · UniProtKB (1)

Boca-dependent maturation of beta-propeller/EGF modules in low-density lipoprotein receptor proteins.

Culi J., Springer T.A., Mann R.S.

EMBO J. 23:1372-1380(2004) · UniProtKB (1) · Mapped (16)

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