1 - 25 of 85 results for author:"Spraggon G." in Literature citations
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| FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. Nesta B., Spraggon G., Alteri C., Moriel D.G., Rosini R., Veggi D., Smith S., Bertoldi I., Pastorello I., Ferlenghi I. et al. MBio 3:0-0(2012) · UniProtKB (1) |
| Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197. Malito E., Bursulaya B., Chen C., Lo Surdo P., Picchianti M., Balducci E., Biancucci M., Brock A., Berti F., Bottomley M.J. et al. Proc. Natl. Acad. Sci. U.S.A. 109:5229-5234(2012) · Mapped (1) |
| Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Cellitti S.E., Shaffer J., Jones D.H., Mukherjee T., Gurumurthy M., Bursulaya B., Boshoff H.I., Choi I., Nayyar A., Lee Y.S. et al. |
| An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity. Young D.D., Young T.S., Jahnz M., Ahmad I., Spraggon G., Schultz P.G. Biochemistry 50:1894-1900(2011) · Mapped (1) |
| Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain. Lee C.C., Jia Y., Li N., Sun X., Ng K., Ambing E., Gao M.Y., Hua S., Chen C., Kim S. et al. |
| Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus. Spraggon G., Koesema E., Scarselli M., Malito E., Biagini M., Norais N., Emolo C., Barocchi M.A., Giusti F., Hilleringmann M. et al. PLoS ONE 5:e10919-e10919(2010) · UniProtKB (1) |
| Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Spraggon G., Hornsby M., Shipway A., Tully D.C., Bursulaya B., Danahay H., Harris J.L., Lesley S.A. Protein Sci. 18:1081-1094(2009) · UniProtKB (1) · Mapped (3) |
| Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase. Xu Q., Sudek S., McMullan D., Miller M.D., Geierstanger B., Jones D.H., Krishna S.S., Spraggon G., Bursalay B., Abdubek P. et al. Structure 17:303-313(2009) · UniProtKB (1) |
| Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Tully D.C., Vidal A., Chatterjee A.K., Williams J.A., Roberts M.J., Petrassi H.M., Spraggon G., Bursulaya B., Pacoma R., Shipway A. et al. Bioorg. Med. Chem. Lett. 18:5895-5899(2008) · Mapped (1) |
| Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis. Gengenbacher M., Xu T., Niyomrattanakit P., Spraggon G., Dick T. FEMS Microbiol. Lett. 287:128-135(2008) · UniProtKB (1) |
| Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold. Kozbial P., Xu Q., Chiu H.J., McMullan D., Krishna S.S., Miller M.D., Abdubek P., Acosta C., Astakhova T., Axelrod H.L. et al. Proteins 71:1589-1596(2008) · UniProtKB (2) |
| Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution. Mathews I.I., McMullan D., Miller M.D., Canaves J.M., Elsliger M.A., Floyd R., Grzechnik S.K., Jaroszewski L., Klock H.E., Koesema E. et al. Proteins 70:603-608(2008) · UniProtKB (1) |
| Crystal structure of human Pus10, a novel pseudouridine synthase. McCleverty C.J., Hornsby M., Spraggon G., Kreusch A. J. Mol. Biol. 373:1243-1254(2007) · UniProtKB (1) · Mapped (1) |
| The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Hampton E.N., Knuth M.W., Li J., Harris J.L., Lesley S.A., Spraggon G. Proc. Natl. Acad. Sci. U.S.A. 104:14604-14609(2007) · Mapped (3) |
| Integration of inositol phosphate signaling pathways via human ITPK1. Chamberlain P.P., Qian X., Stiles A.R., Cho J., Jones D.H., Lesley S.A., Grabau E.A., Shears S.B., Spraggon G. J. Biol. Chem. 282:28117-28125(2007) · UniProtKB (1) · Mapped (4) |
| Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode. Inagaki H., Tsuruoka H., Hornsby M., Lesley S.A., Spraggon G., Ellman J.A. J. Med. Chem. 50:2693-2699(2007) · UniProtKB (1) |
| Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function. Premkumar L., Rife C.L., Sri Krishna S., McMullan D., Miller M.D., Abdubek P., Ambing E., Astakhova T., Axelrod H.L., Canaves J.M. et al. Proteins 68:418-424(2007) · UniProtKB (1) |
| Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution. Weekes D., Miller M.D., Krishna S.S., McMullan D., McPhillips T.M., Acosta C., Canaves J.M., Elsliger M.A., Floyd R., Grzechnik S.K. et al. Proteins 67:247-252(2007) · UniProtKB (1) |
| A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Kinderman F.S., Kim C., von Daake S., Ma Y., Pham B.Q., Spraggon G., Xuong N.H., Jennings P.A., Taylor S.S. Mol. Cell 24:397-408(2006) · Mapped (7) |
| Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method. Patterson A.W., Wood W.J., Hornsby M., Lesley S., Spraggon G., Ellman J.A. J. Med. Chem. 49:6298-6307(2006) · Mapped (1) |
| Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution. Kosloff M., Han G.W., Krishna S.S., Schwarzenbacher R., Fasnacht M., Elsliger M.A., Abdubek P., Agarwalla S., Ambing E., Astakhova T. et al. Proteins 65:527-537(2006) · UniProtKB (1) |
| Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p. Xu Q., Krishna S.S., McMullan D., Schwarzenbacher R., Miller M.D., Abdubek P., Agarwalla S., Ambing E., Astakhova T., Axelrod H.L. et al. Proteins 65:777-782(2006) · UniProtKB (1) |
| Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site. DiDonato M., Krishna S.S., Schwarzenbacher R., McMullan D., Agarwalla S., Brittain S.M., Miller M.D., Abdubek P., Ambing E., Axelrod H.L. et al. Proteins 65:771-776(2006) · Mapped (1) |
| Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers. Tully D.C., Liu H., Chatterjee A.K., Alper P.B., Epple R., Williams J.A., Roberts M.J., Woodmansee D.H., Masick B.T., Tumanut C. et al. Bioorg. Med. Chem. Lett. 16:5112-5117(2006) · Mapped (1) |
| A general strategy for creating "inactive-conformation" abl inhibitors. Okram B., Nagle A., Adrian F.J., Lee C., Ren P., Wang X., Sim T., Xie Y., Wang X., Xia G. et al. Chem. Biol. 13:779-786(2006) · Mapped (1) |