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Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.

Smith K.D., Fu M.A., Brown E.J.

J. Cell Biol. 187:15-23(2009) · Mapped (6)

A role of matrix metalloproteinase-8 in atherosclerosis.

Laxton R.C., Hu Y., Duchene J., Zhang F., Zhang Z., Leung K.Y., Xiao Q., Scotland R.S., Hodgkinson C.P., Smith K. et al.

Circ. Res. 105:921-929(2009) · Mapped (12)

Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats.

Sari Y., Smith K.D., Ali P.K., Rebec G.V.

J. Neurosci. 29:9239-9243(2009) · Mapped (1)

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.

Wellcome Trust Case Control Consortium5

Mol. Psychiatry 0:0-0(2009) · Mapped (10)

Multimeric and trimeric subunit SP-D are interconvertible structures with distinct ligand interaction.

Sorensen G.L., Hoegh S.V., Leth-Larsen R., Thomsen T.H., Floridon C., Smith K., Kejling K., Tornoe I., Crouch E.C., Holmskov U.

Mol. Immunol. 46:3060-3069(2009) · Mapped (1)

Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.

Wellcome Trust Case Control Consortium

Br J Psychiatry 195:23-29(2009) · Mapped (34)

The 2.1 A crystal structure of an acyl-CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl-binding pocket for small branched acyl substrates.

Shah M.B., Ingram-Smith C., Cooper L.L., Qu J., Meng Y., Smith K.S., Gulick A.M.

Proteins 77:685-698(2009) · Mapped (1)

Dominant-negative ALK2 allele associates with congenital heart defects.

Smith K.A., Joziasse I.C., Chocron S., van Dinther M., Guryev V., Verhoeven M.C., Rehmann H., van der Smagt J.J., Doevendans P.A., Cuppen E. et al.

Circulation 119:3062-3069(2009) · Mapped (4)

Cyclic stretch reduces myofibrillar protein synthesis despite increases in FAK and anabolic signalling in L6 cells.

Atherton P.J., Szewczyk N.J., Selby A., Rankin D., Hillier K., Smith K., Rennie M.J., Loughna P.T.

J. Physiol. (Lond.) 587:3719-3727(2009) · Mapped (1)

Essential role for TRPC5 in amygdala function and fear-related behavior.

Riccio A., Li Y., Moon J., Kim K.S., Smith K.S., Rudolph U., Gapon S., Yao G.L., Tsvetkov E., Rodig S.J. et al.

Cell 137:761-772(2009) · Mapped (2)

Structure, stability, and flexibility of ribosomal protein L14e from Sulfolobus solfataricus.

Edmondson S.P., Turri J., Smith K., Clark A., Shriver J.W.

Biochemistry 48:5553-5562(2009) · Mapped (1)

Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcgammaRI versus FcgammaRIIa.

Dai X., Jayapal M., Tay H.K., Reghunathan R., Lin G., Too C.T., Lim Y.T., Chan S.H., Kemeny D.M., Floto R.A. et al.

Blood 114:318-327(2009) · Mapped (3)

Functional pre- mRNA trans-splicing of coactivator CoAA and corepressor RBM4 during stem/progenitor cell differentiation.

Brooks Y.S., Wang G., Yang Z., Smith K.K., Bieberich E., Ko L.

J. Biol. Chem. 284:18033-18046(2009) · UniProtKB (2) · Mapped (12)

Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease.

Gutierrez O.M., Januzzi J.L., Isakova T., Laliberte K., Smith K., Collerone G., Sarwar A., Hoffmann U., Coglianese E., Christenson R. et al.

Circulation 119:2545-2552(2009) · Mapped (2)

Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

Carr E.J., Clatworthy M.R., Lowe C.E., Todd J.A., Wong A., Vyse T.J., Kamesh L., Watts R.A., Lyons P.A., Smith K.G.

BMC Med. Genet. 10:22-22(2009) · Mapped (7)

Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343.

Crouch E., Hartshorn K., Horlacher T., McDonald B., Smith K., Cafarella T., Seaton B., Seeberger P.H., Head J.

Biochemistry 48:3335-3345(2009) · Mapped (1)

Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

Gregorian C., Nakashima J., Le Belle J., Ohab J., Kim R., Liu A., Smith K.B., Groszer M., Garcia A.D., Sofroniew M.V. et al.

J. Neurosci. 29:1874-1886(2009) · Mapped (5)

Mapping QTLs for developmental traits in raspberry from bud break to ripe fruit.

Graham J., Hackett C.A., Smith K., Woodhead M., Hein I., McCallum S.

Theor. Appl. Genet. 118:1143-1155(2009) · UniProtKB (1)

Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.

Urtishak K.A., Smith K.D., Chanoux R.A., Greenberg R.A., Johnson F.B., Brown E.J.

J. Biol. Chem. 284:8777-8785(2009) · Mapped (6)

Distribution of the Na,K-ATPase alpha subunit in the rat spiral ganglion and organ of corti.

McLean W.J., Smith K.A., Glowatzki E., Pyott S.J.

J. Assoc. Res. Otolaryngol. 10:37-49(2009) · Mapped (2)

Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype.

Wellcome Trust Case Control Consortium (WTCCC)

Mol. Psychiatry 0:0-0(2008) · Mapped (53)

Regulation and activity of a zinc uptake regulator, Zur, in Corynebacterium diphtheriae.

Smith K.F., Bibb L.A., Schmitt M.P., Oram D.M.

J. Bacteriol. 191:1595-1603(2009) · UniProtKB (1)

Clustering transfers the translocated Escherichia coli receptor into lipid rafts to stimulate reversible activation of c-Fyn.

Hayward R.D., Hume P.J., Humphreys D., Phillips N., Smith K., Koronakis V.

Cell. Microbiol. 11:433-441(2009) · Mapped (1)

Impact of a constitutively active luteinizing hormone receptor on testicular gene expression and postnatal Leydig cell development.

Coonce M.M., Rabideau A.C., McGee S., Smith K., Narayan P.

Mol. Cell. Endocrinol. 298:33-41(2009) · Mapped (1)

Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans.

Hapiak V.M., Hobson R.J., Hughes L., Smith K., Harris G., Condon C., Komuniecki P., Komuniecki R.W.

Genetics 181:153-163(2009) · Mapped (9)

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