14 results for author:"Slusher B.S." in Literature citations
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| Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis. Rahn K.A., Watkins C.C., Alt J., Rais R., Stathis M., Grishkan I., Crainiceau C.M., Pomper M.G., Rojas C., Pletnikov M.V. et al. Proc. Natl. Acad. Sci. U.S.A. 109:20101-20106(2012) · Mapped (2) |
| Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Le A., Lane A.N., Hamaker M., Bose S., Gouw A., Barbi J., Tsukamoto T., Rojas C.J., Slusher B.S., Zhang H. et al. Cell Metab. 15:110-121(2012) · Mapped (14) |
| Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system. Farah M.H., Pan B.H., Hoffman P.N., Ferraris D., Tsukamoto T., Nguyen T., Wong P.C., Price D.L., Slusher B.S., Griffin J.W. J. Neurosci. 31:5744-5754(2011) · Mapped (8) |
| Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Seltzer M.J., Bennett B.D., Joshi A.D., Gao P., Thomas A.G., Ferraris D.V., Tsukamoto T., Rojas C.J., Slusher B.S., Rabinowitz J.D. et al. Cancer Res. 70:8981-8987(2010) · Mapped (18) |
| Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs. Barinka C., Hlouchova K., Rovenska M., Majer P., Dauter M., Hin N., Ko Y.-S., Tsukamoto T., Slusher B.S., Konvalinka J. et al. J. Mol. Biol. 376:1438-1450(2008) · UniProtKB (1) · Mapped (4) |
| Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II. Barinka C., Rovenska M., Mlcochova P., Hlouchova K., Plechanovova A., Majer P., Tsukamoto T., Slusher B.S., Konvalinka J., Lubkowski J. J. Med. Chem. 50:3267-3273(2007) · UniProtKB (1) |
| Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer. Mesters J.R., Barinka C., Li W., Tsukamoto T., Majer P., Slusher B.S., Konvalinka J., Hilgenfeld R. EMBO J. 25:1375-1384(2006) · UniProtKB (1) |
| Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injury. Bacich D.J., Wozniak K.M., Lu X.C., O'Keefe D.S., Callizot N., Heston W.D., Slusher B.S. J. Neurochem. 95:314-323(2005) · Mapped (2) |
| Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding. Barinka C., Mlcochova P., Sacha P., Hilgert I., Majer P., Slusher B.S., Horejsi V., Konvalinka J. Eur. J. Biochem. 271:2782-2790(2004) · Mapped (5) |
| Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity. Barinka C., Sacha P., Sklenar J., Man P., Bezouska K., Slusher B.S., Konvalinka J. Protein Sci. 13:1627-1635(2004) · UniProtKB (1) · Mapped (4) |
| Effect of middle cerebral artery occlusion on mRNA expression for the sodium-coupled vitamin C transporter SVCT2 in rat brain. Berger U.V., Lu X.C., Liu W., Tang Z., Slusher B.S., Hediger M.A. J. Neurochem. 86:896-906(2003) · Mapped (2) |
| Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Ghadge G.D., Slusher B.S., Bodner A., Canto M.D., Wozniak K., Thomas A.G., Rojas C., Tsukamoto T., Majer P., Miller R.J. et al. Proc. Natl. Acad. Sci. U.S.A. 100:9554-9559(2003) · Mapped (2) |
| Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate. Strisovsky K., Jiraskova J., Barinka C., Majer P., Rojas C., Slusher B.S., Konvalinka J. FEBS Lett. 535:44-48(2003) · Mapped (1) |
| Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II. Barinka C., Rinnova M., Sacha P., Rojas C., Majer P., Slusher B.S., Konvalinka J. J. Neurochem. 80:477-487(2002) · Mapped (4) |