1 - 25 of 101 results for author:"Simon M.C." in Literature citations
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| ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Qing G., Li B., Vu A., Skuli N., Walton Z.E., Liu X., Mayes P.A., Wise D.R., Thompson C.B., Maris J.M. et al. Cancer Cell 22:631-644(2012) · Mapped (4) |
| PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis. Gao Y., Sartori D.J., Li C., Yu Q.C., Kushner J.A., Simon M.C., Diehl J.A. Mol. Cell. Biol. 32:5129-5139(2012) · Mapped (3) |
| Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis. Qi Y., Tian X., Liu J., Han Y., Graham A.M., Simon M.C., Penninger J.M., Carmeliet P., Li S. J. Cell Biol. 198:103-114(2012) · Mapped (11) |
| BNip3 regulates mitochondrial function and lipid metabolism in the liver. Glick D., Zhang W., Beaton M., Marsboom G., Gruber M., Simon M.C., Hart J., Dorn G.W., Brady M.J., Macleod K.F. Mol. Cell. Biol. 32:2570-2584(2012) · Mapped (6) |
| Endothelial HIF-2alpha regulates murine pathological angiogenesis and revascularization processes. Skuli N., Majmundar A.J., Krock B.L., Mesquita R.C., Mathew L.K., Quinn Z.L., Runge A., Liu L., Kim M.N., Liang J. et al. J. Clin. Invest. 122:1427-1443(2012) · Mapped (5) |
| HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Keith B., Johnson R.S., Simon M.C. Nat. Rev. Cancer 12:9-22(2012) · Mapped (16) |
| Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of alpha-ketoglutarate to citrate to support cell growth and viability. Wise D.R., Ward P.S., Shay J.E., Cross J.R., Gruber J.J., Sachdeva U.M., Platt J.M., DeMatteo R.G., Simon M.C., Thompson C.B. Proc. Natl. Acad. Sci. U.S.A. 108:19611-19616(2011) · Mapped (13) |
| O(2) regulates skeletal muscle progenitor differentiation through phosphatidylinositol 3-kinase/AKT signaling. Majmundar A.J., Skuli N., Mesquita R.C., Kim M.N., Yodh A.G., Nguyen-McCarty M., Simon M.C. Mol. Cell. Biol. 32:36-49(2012) · Mapped (15) |
| Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia. Russell R.C., Sufan R.I., Zhou B., Heir P., Bunda S., Sybingco S.S., Greer S.N., Roche O., Heathcote S.A., Chow V.W. et al. Nat. Med. 17:845-853(2011) · Mapped (5) |
| Loss of the Birt-Hogg-Dube tumor suppressor results in apoptotic resistance due to aberrant TGFbeta-mediated transcription. Cash T.P., Gruber J.J., Hartman T.R., Henske E.P., Simon M.C. Oncogene 30:2534-2546(2011) · Mapped (4) |
| Lack of HIF-2alpha in limb bud mesenchyme causes a modest and transient delay of endochondral bone development. Araldi E., Khatri R., Giaccia A.J., Simon M.C., Schipani E. Nat. Med. 17:25-6; author reply 2011:27-9(2011) · Mapped (30) |
| Hypoxia-inducible factors and the response to hypoxic stress. Majmundar A.J., Wong W.J., Simon M.C. Mol. Cell 40:294-309(2010) · Mapped (13) |
| Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha. Qing G., Skuli N., Mayes P.A., Pawel B., Martinez D., Maris J.M., Simon M.C. Cancer Res. 70:10351-10361(2010) · Mapped (7) |
| O2 regulates stem cells through Wnt/beta-catenin signalling. Mazumdar J., O'Brien W.T., Johnson R.S., LaManna J.C., Chavez J.C., Klein P.S., Simon M.C. Nat. Cell Biol. 12:1007-1013(2010) · Mapped (3) |
| HIF-2alpha deletion promotes Kras-driven lung tumor development. Mazumdar J., Hickey M.M., Pant D.K., Durham A.C., Sweet-Cordero A., Vachani A., Jacks T., Chodosh L.A., Kissil J.L., Simon M.C. et al. Proc. Natl. Acad. Sci. U.S.A. 107:14182-14187(2010) · Mapped (11) |
| Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. Imtiyaz H.Z., Williams E.P., Hickey M.M., Patel S.A., Durham A.C., Yuan L.J., Hammond R., Gimotty P.A., Keith B., Simon M.C. J. Clin. Invest. 120:2699-2714(2010) · Mapped (3) |
| Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina. Weidemann A., Krohne T.U., Aguilar E., Kurihara T., Takeda N., Dorrell M.I., Simon M.C., Haase V.H., Friedlander M., Johnson R.S. Glia 58:1177-1185(2010) · Mapped (16) |
| von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Kurihara T., Kubota Y., Ozawa Y., Takubo K., Noda K., Simon M.C., Johnson R.S., Suematsu M., Tsubota K., Ishida S. et al. Development 137:1563-1571(2010) · Mapped (53) |
| Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. Patel S.A., Simon M.C. J. Biol. Chem. 285:15587-15598(2010) · Mapped (12) |
| The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice. Hickey M.M., Richardson T., Wang T., Mosqueira M., Arguiri E., Yu H., Yu Q.C., Solomides C.C., Morrisey E.E., Khurana T.S. et al. J. Clin. Invest. 120:827-839(2010) · Mapped (7) |
| Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. Takeda N., O'Dea E.L., Doedens A., Kim J.W., Weidemann A., Stockmann C., Asagiri M., Simon M.C., Hoffmann A., Johnson R.S. Genes Dev. 24:491-501(2010) · Mapped (5) |
| EPAS1 Is Required for Spermatogenesis in the Postnatal Mouse Testis. Gruber M., Mathew L.K., Runge A.C., Garcia J.A., Simon M.C. Biol. Reprod. 82:1227-1236(2010) · Mapped (2) |
| The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. Weidemann A., Kerdiles Y.M., Knaup K.X., Rafie C.A., Boutin A.T., Stockmann C., Takeda N., Scadeng M., Shih A.Y., Haase V.H. et al. J. Clin. Invest. 119:3373-3383(2009) · Mapped (16) |
| HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Bertout J.A., Majmundar A.J., Gordan J.D., Lam J.C., Ditsworth D., Keith B., Brown E.J., Nathanson K.L., Simon M.C. Proc. Natl. Acad. Sci. U.S.A. 106:14391-14396(2009) · Mapped (4) |
| Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Fang H.Y., Hughes R., Murdoch C., Coffelt S.B., Biswas S.K., Harris A.L., Johnson R.S., Imityaz H.Z., Simon M.C., Fredlund E. et al. Blood 114:844-859(2009) · Mapped (5) |