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The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Consortium of Investigators of Modifiers of BRCA1/2

Br. J. Cancer 101:1456-1460(2009) · Mapped (100)

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer

Hum. Mol. Genet. 18:4442-4456(2009) · Mapped (65)

Analysis of 17beta-hydroxysteroid dehydrogenase types 5, 7, and 12 genetic sequence variants in breast cancer cases from French Canadian Families with high risk of breast and ovarian cancer.

Plourde M., Ferland A., Soucy P., Hamdi Y., Tranchant M., Durocher F., Sinilnikova O., The V.L., Simard J.

J. Steroid Biochem. Mol. Biol. 116:134-153(2009) · Mapped (12)

Reproductive and hormonal factors, and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: results from the International BRCA1/2 Carrier Cohort Study.

Antoniou A.C., Rookus M., Andrieu N., Brohet R., Chang-Claude J., Peock S., Cook M., Evans D.G., Eeles R., Nogues C. et al.

Cancer Epidemiol. Biomarkers Prev. 18:601-610(2009) · Mapped (43)

De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury.

Gerzanich V., Woo S.K., Vennekens R., Tsymbalyuk O., Ivanova S., Ivanov A., Geng Z., Chen Z., Nilius B., Flockerzi V. et al.

Nat. Med. 15:185-191(2009) · Mapped (2)

Sulfonylurea receptor 1 in the germinal matrix of premature infants.

Simard J.M., Castellani R.J., Ivanova S., Koltz M.T., Gerzanich V.

Pediatr. Res. 64:648-652(2008) · Mapped (3)

No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study.

Rebbeck T.R., Antoniou A.C., Llopis T.C., Nevanlinna H., Aittomaki K., Simard J., Spurdle A.B., Couch F.J., Pereira L.H., Greene M.H. et al.

Breast Cancer Res. Treat. 115:185-192(2009) · Mapped (52)

Mutational analysis of the breast cancer susceptibility gene BRIP1 /BACH1/FANCJ in high-risk non-BRCA1/BRCA2 breast cancer families.

Guenard F., Labrie Y., Ouellette G., Joly Beauparlant C., Simard J., Durocher F.

J. Hum. Genet. 53:579-591(2008) · Mapped (1)

Mutation analysis and characterization of HSD17B2 sequence variants in breast cancer cases from French Canadian families with high risk of breast and ovarian cancer.

Plourde M., Manhes C., Leblanc G., Durocher F., Dumont M., Sinilnikova O., Simard J.

J. Mol. Endocrinol. 40:161-172(2008) · Mapped (2)

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Kathleen Cuningham Consortium for Research into Familial Breast Cancer

Am. J. Hum. Genet. 82:937-948(2008) · Mapped (58)

Analysis of GADD45A sequence variations in French Canadian families with high risk of breast cancer.

Desjardins S., Ouellette G., Labrie Y., Simard J., Durocher F.

J. Hum. Genet. 53:490-498(2008) · Mapped (4)

Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR.

Michalczyk A., Kluter S., Rode H.B., Simard J.R., Grutter C., Rabiller M., Rauh D.

Bioorg. Med. Chem. 16:3482-3488(2008) · Mapped (1)

Characterization of HSD17B1 sequence variants in breast cancer cases from French Canadian families with high risk of breast and ovarian cancer.

Plourde M., Samson C., Durocher F., Sinilnokova O., Simard J.

J. Steroid Biochem. Mol. Biol. 109:115-128(2008) · Mapped (7)

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.

German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC)

Am. J. Hum. Genet. 81:1186-1200(2007) · Mapped (50)

Genetic sequence variations and ADPRT haplotype analysis in French Canadian families with high risk of breast cancer.

Durocher F., Labrie Y., Ouellette G., Simard J.

J. Hum. Genet. 52:963-977(2007) · Mapped (9)

Autocrine TGF-beta1 mediates angiotensin II-induced proliferative response of cerebral vessels in vivo.

Yurovsky V.V., Gerzanich V., Ivanova S., Dong Y., Tsymbalyuk O., Simard J.M.

Am. J. Hypertens. 20:950-956(2007) · Mapped (1)

Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury.

Simard J.M., Tsymbalyuk O., Ivanov A., Ivanova S., Bhatta S., Geng Z., Woo S.K., Gerzanich V.

J. Clin. Invest. 117:2105-2113(2007) · Mapped (1)

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.

Consortium of Investigators of Modifiers of BRCA1/2

Cancer Epidemiol. Biomarkers Prev. 16:1416-1421(2007) · Mapped (49)

Mutation analysis and characterization of ATR sequence variants in breast cancer cases from high-risk French Canadian breast/ovarian cancer families.

Durocher F., Labrie Y., Soucy P., Sinilnikova O., Labuda D., Bessette P., Chiquette J., Laframboise R., Lepine J., Lesperance B. et al.

BMC Cancer 6:230-230(2006) · Mapped (1)

Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French-Canadian families with high risk of breast and ovarian cancer.

Simard J., Dumont M., Moisan A.M., Gaborieau V., Malouin H., Durocher F., Chiquette J., Plante M., Avard D., Bessette P. et al.

J. Med. Genet. 44:107-121(2007) · Mapped (43)

EGF and HB-EGF modulate inward potassium current in human bladder urothelial cells from normal and interstitial cystitis patients.

Sun Y., Chen M., Lowentritt B.H., Van Zijl P.S., Koch K.R., Keay S., Simard J.M., Chai T.C.

Am. J. Physiol., Cell Physiol. 292:C106-14(2007) · Mapped (7)

No Evidence of BRCA1/2 genomic rearrangements in high-risk French-Canadian breast/ovarian cancer families.

Moisan A.M., Fortin J., Dumont M., Samson C., Bessette P., Chiquette J., Laframboise R., Lepine J., Lesperance B., Pichette R. et al.

Genet. Test. 10:104-115(2006) · Mapped (43)

Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes.

Qin K., Zhao L., Tang Y., Bhatta S., Simard J.M., Zhao R.Y.

Neuroscience 141:1375-1388(2006) · Mapped (1)

Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke.

Simard J.M., Chen M., Tarasov K.V., Bhatta S., Ivanova S., Melnitchenko L., Tsymbalyuk N., West G.A., Gerzanich V.

Nat. Med. 12:433-440(2006) · Mapped (1)

The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer

Cancer Epidemiol. Biomarkers Prev. 15:76-79(2006) · Mapped (8)

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