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11 results for author:"Shpiro N." in Literature citations

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Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors.

Najafov A., Shpiro N., Alessi D.R.

Biochem. J. 448:285-295(2012) · Mapped (9)

Essential role for IKKbeta in production of type 1 interferons by plasmacytoid dendritic cells.

Pauls E., Shpiro N., Peggie M., Young E.R., Sorcek R.J., Tan L., Choi H.G., Cohen P.

J. Biol. Chem. 287:19216-19228(2012) · Mapped (7)

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes.

Hjerpe R., Thomas Y., Chen J., Zemla A., Curran S., Shpiro N., Dick L.R., Kurz T.

Biochem. J. 441:927-936(2012) · Mapped (1)

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.

Huang X., Wullschleger S., Shpiro N., McGuire V.A., Sakamoto K., Woods Y.L., McBurnie W., Fleming S., Alessi D.R.

Biochem. J. 412:211-221(2008) · Mapped (11)

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

Goransson O., McBride A., Hawley S.A., Ross F.A., Shpiro N., Foretz M., Viollet B., Hardie D.G., Sakamoto K.

J. Biol. Chem. 282:32549-32560(2007) · Mapped (17)

GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels.

Dorfmueller H.C., Borodkin V.S., Schimpl M., Shepherd S.M., Shpiro N.A., van Aalten D.M.

J. Am. Chem. Soc. 128:16484-16485(2006) · Mapped (2)

CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway.

Rousseau S., Dolado I., Beardmore V., Shpiro N., Marquez R., Nebreda A.R., Arthur J.S., Case L.M., Tessier-Lavigne M., Gaestel M. et al.

Cell. Signal. 18:1897-1905(2006) · Mapped (3)

The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1.

Buxade M., Parra J.L., Rousseau S., Shpiro N., Marquez R., Morrice N., Bain J., Espel E., Proud C.G.

Immunity 23:177-189(2005) · UniProtKB (2)

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.

McManus E.J., Sakamoto K., Armit L.J., Ronaldson L., Shpiro N., Marquez R., Alessi D.R.

EMBO J. 24:1571-1583(2005) · UniProtKB (2) · Mapped (6)

Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.

Murray J.T., Campbell D.G., Morrice N., Auld G.C., Shpiro N., Marquez R., Peggie M., Bain J., Bloomberg G.B., Grahammer F. et al.

Biochem. J. 384:477-488(2004) · UniProtKB (3) · Mapped (20)

Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element.

Finlay D., Patel S., Dickson L.M., Shpiro N., Marquez R., Rhodes C.J., Sutherland C.

BMC Mol. Biol. 5:15-15(2004) · Mapped (1)

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