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1 - 25 of 79 results for author:"Shinkai Y." in Literature citations

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Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.

Tan S.L., Nishi M., Ohtsuka T., Matsui T., Takemoto K., Kamio-Miura A., Aburatani H., Shinkai Y., Kageyama R.

Development 139:3806-3816(2012) · Mapped (152)

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.

Nakamura T., Liu Y.J., Nakashima H., Umehara H., Inoue K., Matoba S., Tachibana M., Ogura A., Shinkai Y., Nakano T.

Nature 486:415-419(2012) · UniProtKB (2)

Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a.

Yamamizu K., Fujihara M., Tachibana M., Katayama S., Takahashi A., Hara E., Imai H., Shinkai Y., Yamashita J.K.

Cell Stem Cell 10:759-770(2012) · Mapped (29)

DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells.

Takahashi A., Imai Y., Yamakoshi K., Kuninaka S., Ohtani N., Yoshimoto S., Hori S., Tachibana M., Anderton E., Takeuchi T. et al.

Mol. Cell 45:123-131(2012) · Mapped (6)

MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.

Chang Y., Sun L., Kokura K., Horton J.R., Fukuda M., Espejo A., Izumi V., Koomen J.M., Bedford M.T., Zhang X. et al.

Nat. Commun. 2:533-533(2011) · UniProtKB (2) · Mapped (5)

HP1gamma links histone methylation marks to meiotic synapsis in mice.

Takada Y., Naruse C., Costa Y., Shirakawa T., Tachibana M., Sharif J., Kezuka-Shiotani F., Kakiuchi D., Masumoto H., Shinkai Y. et al.

Development 138:4207-4217(2011) · Mapped (14)

DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs.

Karimi M.M., Goyal P., Maksakova I.A., Bilenky M., Leung D., Tang J.X., Shinkai Y., Mager D.L., Jones S., Hirst M. et al.

Cell Stem Cell 8:676-687(2011) · Mapped (17)

Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing.

Leung D.C., Dong K.B., Maksakova I.A., Goyal P., Appanah R., Lee S., Tachibana M., Shinkai Y., Lehnertz B., Mager D.L. et al.

Proc. Natl. Acad. Sci. U.S.A. 108:5718-5723(2011) · Mapped (14)

Behavioral choice between conflicting alternatives is regulated by a receptor guanylyl cyclase, GCY-28, and a receptor tyrosine kinase, SCD-2, in AIA interneurons of Caenorhabditis elegans.

Shinkai Y., Yamamoto Y., Fujiwara M., Tabata T., Murayama T., Hirotsu T., Ikeda D.D., Tsunozaki M., Iino Y., Bargmann C.I. et al.

J. Neurosci. 31:3007-3015(2011) · Mapped (6)

Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury.

Toyama T., Shinkai Y., Yasutake A., Uchida K., Yamamoto M., Kumagai Y.

Environ. Health Perspect. 119:1117-1122(2011) · Mapped (2)

Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases.

Chang Y., Ganesh T., Horton J.R., Spannhoff A., Liu J., Sun A., Zhang X., Bedford M.T., Shinkai Y., Snyder J.P. et al.

J. Mol. Biol. 400:1-7(2010) · UniProtKB (1)

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

Matsui T., Leung D., Miyashita H., Maksakova I.A., Miyachi H., Kimura H., Tachibana M., Lorincz M.C., Shinkai Y.

Nature 464:927-931(2010) · Mapped (3)

Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice.

Balemans M.C., Huibers M.M., Eikelenboom N.W., Kuipers A.J., van Summeren R.C., Pijpers M.M., Tachibana M., Shinkai Y., van Bokhoven H., Van der Zee C.E.

Behav. Brain Res. 208:47-55(2010) · Mapped (10)

Cilostazol induces metallothionein expression in vascular cells.

Fujiwara Y., Kitagawa T., Shinkai Y., Kaji T., Satoh M.

Yakugaku Zasshi 129:1415-1422(2009) · Mapped (4)

Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice.

Inagaki T., Tachibana M., Magoori K., Kudo H., Tanaka T., Okamura M., Naito M., Kodama T., Shinkai Y., Sakai J.

Genes Cells 14:991-1001(2009) · Mapped (13)

Expression of the mouse PR domain protein Prdm8 in the developing central nervous system.

Komai T., Iwanari H., Mochizuki Y., Hamakubo T., Shinkai Y.

Gene Expr. Patterns 9:503-514(2009) · Mapped (66)

Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.

Link P.A., Gangisetty O., James S.R., Woloszynska-Read A., Tachibana M., Shinkai Y., Karpf A.R.

Mol. Cancer Res. 7:851-862(2009) · Mapped (6)

Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

Shinkai Y., Sumi D., Toyama T., Kaji T., Kumagai Y.

Toxicol. Appl. Pharmacol. 237:232-236(2009) · Mapped (4)

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.

Shirato H., Ogawa S., Nakajima K., Inagawa M., Kojima M., Tachibana M., Shinkai Y., Takeuchi T.

J. Biol. Chem. 284:733-739(2009) · UniProtKB (1) · Mapped (33)

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.

Tachibana M., Matsumura Y., Fukuda M., Kimura H., Shinkai Y.

EMBO J. 27:2681-2690(2008) · UniProtKB (2) · Mapped (15)

DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity.

Dong K.B., Maksakova I.A., Mohn F., Leung D., Appanah R., Lee S., Yang H.W., Lam L.L., Mager D.L., Schubeler D. et al.

EMBO J. 27:2691-2701(2008) · Mapped (8)

Distinct roles of TRF1 in the regulation of telomere structure and lengthening.

Okamoto K., Iwano T., Tachibana M., Shinkai Y.

J. Biol. Chem. 283:23981-23988(2008) · Mapped (3)

Functional analysis of histone methyltransferase g9a in B and T lymphocytes.

Thomas L.R., Miyashita H., Cobb R.M., Pierce S., Tachibana M., Hobeika E., Reth M., Shinkai Y., Oltz E.M.

J. Immunol. 181:485-493(2008) · Mapped (18)

Characterization of Drosophila G9a in vivo and identification of genetic interactants.

Kato Y., Kato M., Tachibana M., Shinkai Y., Yamaguchi M.

Genes Cells 13:703-722(2008) · Mapped (4)

Protein lysine methyltransferase G9a acts on non-histone targets.

Rathert P., Dhayalan A., Murakami M., Zhang X., Tamas R., Jurkowska R., Komatsu Y., Shinkai Y., Cheng X., Jeltsch A.

Nat. Chem. Biol. 4:344-346(2008) · UniProtKB (8)

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