1 - 25 of
49
results
for author:"Shiloh Y."
in Literature Citations
| Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system. Baranes K., Raz-Prag D., Nitzan A., Galron R., Ashery-Padan R., Rotenstreich Y., Assaf Y., Shiloh Y., Wang Z.Q., Barzilai A. et al. Exp. Neurol. 218:24-32(2009) · Mapped (3) |
| Activation of ATM depends on chromatin interactions occurring before induction of DNA damage. Kim Y.C., Gerlitz G., Furusawa T., Catez F., Nussenzweig A., Oh K.S., Kraemer K.H., Shiloh Y., Bustin M. Nat. Cell Biol. 11:92-96(2009) · Mapped (6) |
| Analysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repair. Kirshner M., Rathavs M., Nizan A., Essers J., Kanaar R., Shiloh Y., Barzilai A. DNA Repair (Amst.) 8:253-261(2009) · Mapped (8) |
| The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Shema E., Tirosh I., Aylon Y., Huang J., Ye C., Moskovits N., Raver-Shapira N., Minsky N., Pirngruber J., Tarcic G. et al. Genes Dev. 22:2664-2676(2008) · Mapped (3) |
| ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Goodarzi A.A., Noon A.T., Deckbar D., Ziv Y., Shiloh Y., Lobrich M., Jeggo P.A. Mol. Cell 31:167-177(2008) · Mapped (5) |
| WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks. Cheng W.H., Muftic D., Muftuoglu M., Dawut L., Morris C., Helleday T., Shiloh Y., Bohr V.A. Mol. Biol. Cell 19:3923-3933(2008) · Mapped (10) |
| Ataxia-telangiectasia: mild neurological presentation despite null ATM mutation and severe cellular phenotype. Alterman N., Fattal-Valevski A., Moyal L., Crawford T.O., Lederman H.M., Ziv Y., Shiloh Y. Am. J. Med. Genet. A 143A:1827-1834(2007) · Mapped (8) |
| ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y. et al. Science 316:1160-1166(2007) · UniProtKB (755) |
| Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. Chen B.P., Uematsu N., Kobayashi J., Lerenthal Y., Krempler A., Yajima H., Lobrich M., Shiloh Y., Chen D.J. J. Biol. Chem. 282:6582-6587(2007) · Mapped (10) |
| Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage. Pereg Y., Lam S., Teunisse A., Biton S., Meulmeester E., Mittelman L., Buscemi G., Okamoto K., Taya Y., Shiloh Y. et al. Mol. Cell. Biol. 26:6819-6831(2006) · Mapped (23) |
| Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells. Biton S., Dar I., Mittelman L., Pereg Y., Barzilai A., Shiloh Y. J. Biol. Chem. 281:17482-17491(2006) · Mapped (8) |
| Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue. Rashi-Elkeles S., Elkon R., Weizman N., Linhart C., Amariglio N., Sternberg G., Rechavi G., Barzilai A., Shamir R., Shiloh Y. Oncogene 25:1584-1592(2006) · Mapped (2) |
| Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia. Ziv S., Brenner O., Amariglio N., Smorodinsky N.I., Galron R., Carrion D.V., Zhang W., Sharma G.G., Pandita R.K., Agarwal M. et al. Hum. Mol. Genet. 14:2929-2943(2005) · Mapped (10) |
| ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation. Meulmeester E., Pereg Y., Shiloh Y., Jochemsen A.G. Cell Cycle 4:1166-1170(2005) · Mapped (77) |
| ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Bhoumik A., Takahashi S., Breitweiser W., Shiloh Y., Jones N., Ronai Z. Mol. Cell 18:577-587(2005) · Mapped (21) |
| Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage. Pereg Y., Shkedy D., de Graaf P., Meulmeester E., Edelson-Averbukh M., Salek M., Biton S., Teunisse A.F., Lehmann W.D., Jochemsen A.G. et al. Proc. Natl. Acad. Sci. U.S.A. 102:5056-5061(2005) · Mapped (46) |
| Requirement of the MRN complex for ATM activation by DNA damage. Uziel T., Lerenthal Y., Moyal L., Andegeko Y., Mittelman L., Shiloh Y. EMBO J. 22:5612-5621(2003) · Mapped (10) |
| ATM and related protein kinases: safeguarding genome integrity. Shiloh Y. Nat. Rev. Cancer 3:155-168(2003) · Mapped (8) |
| Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains. Weizman N., Shiloh Y., Barzilai A. J. Biol. Chem. 278:6741-6747(2003) · Mapped (4) |
| Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366. Sapkota G.P., Deak M., Kieloch A., Morrice N., Goodarzi A.A., Smythe C., Shiloh Y., Lees-Miller S.P., Alessi D.R. Biochem. J. 368:507-516(2002) · Mapped (14) |
| ATM: from phenotype to functional genomics--and back. Shiloh Y. Ernst Schering Res. Found. Workshop 2002:51-70(2002) · Mapped (8) |
| Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice. Stern N., Hochman A., Zemach N., Weizman N., Hammel I., Shiloh Y., Rotman G., Barzilai A. J. Biol. Chem. 277:602-608(2002) · Mapped (2) |
| Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype. Spring K., Cross S., Li C., Watters D., Ben-Senior L., Waring P., Ahangari F., Lu S.L., Chen P., Misko I. et al. Cancer Res. 61:4561-4568(2001) · Mapped (2) |
| Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks. Kishi S., Zhou X.Z., Ziv Y., Khoo C., Hill D.E., Shiloh Y., Lu K.P. J. Biol. Chem. 276:29282-29291(2001) · UniProtKB (2) |
| ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. Maya R., Balass M., Kim S.T., Shkedy D., Leal J.F., Shifman O., Moas M., Buschmann T., Ronai Z., Shiloh Y. et al. Genes Dev. 15:1067-1077(2001) · Mapped (2) |
