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Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice.

Honda S., Kurita N., Miyamoto A., Cho Y., Usui K., Takeshita K., Takahashi S., Yasui T., Kikutani H., Kinoshita T. et al.

Proc. Natl. Acad. Sci. U.S.A. 106:11230-11235(2009) · Mapped (1)

Selective killing of hypoxia-inducible factor-1-active cells improves survival in a mouse model of invasive and metastatic pancreatic cancer.

Kizaka-Kondoh S., Itasaka S., Zeng L., Tanaka S., Zhao T., Takahashi Y., Shibuya K., Hirota K., Semenza G.L., Hiraoka M.

Clin. Cancer Res. 15:3433-3441(2009) · Mapped (8)

The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors.

Harada H., Itasaka S., Kizaka-Kondoh S., Shibuya K., Morinibu A., Shinomiya K., Hiraoka M.

J. Biol. Chem. 284:5332-5342(2009) · Mapped (16)

InPSR26, a putative membrane protein, regulates programmed cell death during petal senescence in Japanese morning glory.

Shibuya K., Yamada T., Suzuki T., Shimizu K., Ichimura K.

Plant Physiol. 149:816-824(2009) · UniProtKB (1)

Accelerated tumor growth in mice deficient in DNAM-1 receptor.

Iguchi-Manaka A., Kai H., Yamashita Y., Shibata K., Tahara-Hanaoka S., Honda S., Yasui T., Kikutani H., Shibuya K., Shibuya A.

J. Exp. Med. 205:2959-2964(2008) · Mapped (6)

Identification of the Fcalpha/muR isoform specifically expressed in the kidney tubules.

Kurita N., Honda S., Usui K., Shimizu Y., Miyamoto A., Tahara-Hanaoka S., Shibuya K., Shibuya A.

Mol. Immunol. 46:749-753(2009) · Mapped (3)

Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer.

Haugen A.C., Goel A., Yamada K., Marra G., Nguyen T.P., Nagasaka T., Kanazawa S., Koike J., Kikuchi Y., Zhong X. et al.

Cancer Res. 68:8465-8472(2008) · Mapped (3)

Identification of the putative protein phosphatase gene PTC1 as a virulence-related gene using a silkworm model of Candida albicans infection.

Hanaoka N., Takano Y., Shibuya K., Fugo H., Uehara Y., Niimi M.

Eukaryotic Cell 7:1640-1648(2008) · Mapped (1)

Clinical significance of aberrant methylation of prostaglandin E receptor 2 (PTGER2) in nonsmall cell lung cancer: association with prognosis, PTGER2 expression, and epidermal growth factor receptor mutation.

Tian L., Suzuki M., Nakajima T., Kubo R., Sekine Y., Shibuya K., Hiroshima K., Nakatani Y., Fujisawa T., Yoshino I.

Cancer 113:1396-1403(2008) · Mapped (1)

LFA-1 decreases the antigen dose for T cell activation in vivo.

Wang Y., Shibuya K., Yamashita Y., Shirakawa J., Shibata K., Kai H., Yokosuka T., Saito T., Honda S., Tahara-Hanaoka S. et al.

Int. Immunol. 20:1119-1127(2008) · Mapped (10)

Aberrant methylation of CXCL12 in non-small cell lung cancer is associated with an unfavorable prognosis.

Suzuki M., Mohamed S., Nakajima T., Kubo R., Tian L., Fujiwara T., Suzuki H., Nagato K., Chiyo M., Motohashi S. et al.

Int. J. Oncol. 33:113-119(2008) · Mapped (7)

Carpal tunnel syndrome and plasma beta2-microglobulin concentration in hemodialysis patients.

Shin J., Nishioka M., Shinko S., Shibuya K., Sugiki M., Kasumoto H., Fudo A., Bito Y., Fujita Y., Komaba K.

Ther Apher Dial 12:62-66(2008) · Mapped (6)

Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells.

Can I., Tahara-Hanaoka S., Hitomi K., Nakano T., Nakahashi-Oda C., Kurita N., Honda S., Shibuya K., Shibuya A.

J. Immunol. 180:207-213(2008) · UniProtKB (1)

Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer.

Suzuki M., Shigematsu H., Nakajima T., Kubo R., Motohashi S., Sekine Y., Shibuya K., Iizasa T., Hiroshima K., Nakatani Y. et al.

Clin. Cancer Res. 13:6087-6092(2007) · Mapped (16)

Significance of HIF-1-active cells in angiogenesis and radioresistance.

Harada H., Kizaka-Kondoh S., Li G., Itasaka S., Shibuya K., Inoue M., Hiraoka M.

Oncogene 26:7508-7516(2007) · Mapped (8)

Activation of neutrophils by a novel triggering immunoglobulin-like receptor MAIR-IV.

Nakano T., Tahara-Hanaoka S., Nakahashi C., Can I., Totsuka N., Honda S., Shibuya K., Shibuya A.

Mol. Immunol. 45:289-294(2008) · Mapped (1)

Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus.

Murakami M., Shibuya K., Nakayama T., Nishino T., Yoshimura T., Hemmi H.

FEBS J. 274:805-814(2007) · UniProtKB (1)

A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.

Wang Y., Kai H., Chang F., Shibata K., Tahara-Hanaoka S., Honda S., Shibuya A., Shibuya K.

Biochem. Biophys. Res. Commun. 353:857-862(2007) · Mapped (5)

Dual assemblies of an activating immune receptor, MAIR-II, with ITAM-bearing adapters DAP12 and FcRgamma chain on peritoneal macrophages.

Nakahashi C., Tahara-Hanaoka S., Totsuka N., Okoshi Y., Takai T., Ohkohchi N., Honda S., Shibuya K., Shibuya A.

J. Immunol. 178:765-770(2007) · UniProtKB (2) · Mapped (2)

Th1 and type 1 cytotoxic T cells dominate responses in T-bet overexpression transgenic mice that develop contact dermatitis.

Ishizaki K., Yamada A., Yoh K., Nakano T., Shimohata H., Maeda A., Fujioka Y., Morito N., Kawachi Y., Shibuya K. et al.

J. Immunol. 178:605-612(2007) · Mapped (3)

Molecular characteristics of IgA and IgM Fc binding to the Fcalpha/muR.

Cho Y., Usui K., Honda S., Tahara-Hanaoka S., Shibuya K., Shibuya A.

Biochem. Biophys. Res. Commun. 345:474-478(2006) · UniProtKB (1)

LFA-1-dependent lipid raft recruitment of DNAM-1 (CD226) in CD4+ T cell.

Shirakawa J., Wang Y., Tahara-Hanaoka S., Honda S., Shibuya K., Shibuya A.

Int. Immunol. 18:951-957(2006) · Mapped (16)

Comment on "CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions".

Shibuya K., Shibata K., Tahara-Hanaoka S., Shibuya A.

J. Immunol. 176:3855; author reply 2006:3856-3856(2006) · Mapped (6)

Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor.

Tahara-Hanaoka S., Shibuya K., Kai H., Miyamoto A., Morikawa Y., Ohkochi N., Honda S., Shibuya A.

Blood 107:1491-1496(2006) · Mapped (13)

Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q.

Shibuya K., Kudoh J., Okui M., Shimizu N.

Biochem. Biophys. Res. Commun. 332:557-568(2005) · UniProtKB (5)

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