| A luminal epithelial stem cell that is a cell of origin for prostate cancer. Wang X., Kruithof-de Julio M., Economides K.D., Walker D., Yu H., Halili M.V., Hu Y.P., Price S.M., Abate-Shen C., Shen M.M.
Nature 461:495-500(2009) · Mapped (6) |
| c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest. Shen M., Yen A.
J. Biol. Chem. 284:25664-25677(2009) · Mapped (6) |
| Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway. Leow C.C., Wang B.E., Ross J., Chan S.M., Zha J., Carano R.A., Frantz G., Shen M.M., de Sauvage F.J., Gao W.Q.
J. Biol. Chem. 284:21057-21065(2009) · Mapped (10) |
| Genetic polymorphism of KCNH2 confers predisposition of acquired atrial fibrillation in Chinese. Wang Q.S., Wang X.F., Chen X.D., Yu J.F., Wang J., Sun J., Lu S.B., Shen M.Y., Lu M., Li Y.G. et al.
J. Cardiovasc. Electrophysiol. 20:1158-1162(2009) · Mapped (13) |
| Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence. Chu X., Dong Y., Shen M., Sun L., Dong C., Wang Y., Wang B., Zhang K., Hua Q., Xu S. et al.
BMC Med. Genet. 10:26-26(2009) · Mapped (2) |
| The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels. Chen C.W., Hwang J.J., Tsai C.T., Su Y.N., Hsueh C.H., Shen M.J., Lai L.P.
J. Hum. Genet. 54:242-247(2009) · Mapped (4) |
| Polymorphisms in the interleukin 3 gene show strong association with susceptibility to Graves' disease in Chinese population. Chu X., Dong C., Lei R., Sun L., Wang Z., Dong Y., Shen M., Wang Y., Wang B., Zhang K. et al.
Genes Immun. 10:260-266(2009) · Mapped (3) |
| Inactivation of p53 and Pten promotes invasive bladder cancer. Puzio-Kuter A.M., Castillo-Martin M., Kinkade C.W., Wang X., Shen T.H., Matos T., Shen M.M., Cordon-Cardo C., Abate-Shen C.
Genes Dev. 23:675-680(2009) · Mapped (53) |
| Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population. Lin R., Wang Y., Wang Y., Fu W., Zhang D., Zheng H., Yu T., Wang Y., Shen M., Lei R. et al.
Pharmacogenet. Genomics 19:310-318(2009) · Mapped (17) |
| Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Oda H., Okamoto I., Murphy N., Chu J., Price S.M., Shen M.M., Torres-Padilla M.E., Heard E., Reinberg D.
Mol. Cell. Biol. 29:2278-2295(2009) · Mapped (10) |
| Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma. Chang K.Y., Shen M.R., Lee M.Y., Wang W.L., Su W.C., Chang W.C., Chen B.K.
J. Biol. Chem. 284:9908-9916(2009) · Mapped (17) |
| Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China. Park S.K., Andreotti G., Sakoda L.C., Gao Y.T., Rashid A., Chen J., Chen B.E., Rosenberg P.S., Shen M.C., Wang B.S. et al.
Carcinogenesis 30:606-614(2009) · Mapped (8) |
| Activation of beta-Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration. Yu X., Wang Y., Jiang M., Bierie B., Roy-Burman P., Shen M.M., Taketo M.M., Wills M., Matusik R.J.
Prostate 69:249-262(2009) · Mapped (61) |
| Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity. Lan Q., Zhang L., Shen M., Jo W.J., Vermeulen R., Li G., Vulpe C., Lim S., Ren X., Rappaport S.M. et al.
Carcinogenesis 30:50-58(2009) · Mapped (48) |
| Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. He H., Wang Y., Guo X., Ramchandani S., Ma J., Shen M.F., Garcia D.A., Deng Y., Multani A.S., You M.J. et al.
Mol. Cell. Biol. 29:229-240(2009) · Mapped (5) |
| Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 beta phosphorylation. Lu Y., Nie D., Witt W.T., Chen Q., Shen M., Xie H., Lai L., Dai Y., Zhang J.
Mol. Cancer Ther. 7:3203-3211(2008) · Mapped (4) |
| Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. Wang X., Desai N., Hu Y.P., Price S.M., Abate-Shen C., Shen M.M.
Dev. Dyn. 237:2963-2972(2008) · Mapped (4) |
| Clinical implications of insulin-like growth factor 1 system in early-stage cervical cancer. Huang Y.F., Shen M.R., Hsu K.F., Cheng Y.M., Chou C.Y.
Br. J. Cancer 99:1096-1102(2008) · Mapped (8) |
| Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. Ko C.Y., Hsu H.C., Shen M.R., Chang W.C., Wang J.M.
J. Biol. Chem. 283:30919-30932(2008) · Mapped (5) |
| Variants of DNA repair genes and the risk of biliary tract cancers and stones: a population-based study in China. Zhang M., Huang W.Y., Andreotti G., Gao Y.T., Rashid A., Chen J., Sakoda L.C., Shen M.C., Wang B.S., Chanock S. et al.
Cancer Epidemiol. Biomarkers Prev. 17:2123-2127(2008) · Mapped (17) |
| Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China. Hsing A.W., Sakoda L.C., Rashid A., Andreotti G., Chen J., Wang B.S., Shen M.C., Chen B.E., Rosenberg P.S., Zhang M. et al.
Cancer Res. 68:6442-6452(2008) · Mapped (120) |
| Epithelial-mesenchymal transition in cervical cancer: correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation. Lee M.Y., Chou C.Y., Tang M.J., Shen M.R.
Clin. Cancer Res. 14:4743-4750(2008) · Mapped (25) |
| Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. Hosgood H.D., Menashe I., Shen M., Yeager M., Yuenger J., Rajaraman P., He X., Chatterjee N., Caporaso N.E., Zhu Y. et al.
Carcinogenesis 29:1938-1943(2008) · Mapped (2,055) |
| Genetic variants in protein kinase C zeta gene and type 2 diabetes risk: a case-control study of a Chinese Han population. Qin L., Zhou L., Wu X., Cheng J., Wang J., Du Y., Hu J., Shen M., Zhou J.
Diabetes Metab. Res. Rev. 24:480-485(2008) · Mapped (5) |
| Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process. Wang Y.T., Chuang J.Y., Shen M.R., Yang W.B., Chang W.C., Hung J.J.
J. Mol. Biol. 380:869-885(2008) · Mapped (5) |
in Literature Citations
