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Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer.

Denzel M.S., Hebbard L.W., Shostak G., Shapiro L., Cardiff R.D., Ranscht B.

Clin. Cancer Res. 15:3256-3264(2009) · Mapped (3)

Morphological and ultrastructural features of Iba1-immunolabeled microglial cells in the hippocampal dentate gyrus.

Shapiro L.A., Perez Z.D., Foresti M.L., Arisi G.M., Ribak C.E.

Brain Res. 1266:29-36(2009) · Mapped (1)

Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood.

Pott G.B., Chan E.D., Dinarello C.A., Shapiro L.

J. Leukoc. Biol. 85:886-895(2009) · Mapped (5)

Mutations in the lipase H gene underlie autosomal recessive woolly hair/hypotrichosis.

Shimomura Y., Wajid M., Petukhova L., Shapiro L., Christiano A.M.

J. Invest. Dermatol. 129:622-628(2009) · Mapped (5)

A polymeric protein anchors the chromosomal origin/ParB complex at a bacterial cell pole.

Bowman G.R., Comolli L.R., Zhu J., Eckart M., Koenig M., Downing K.H., Moerner W.E., Earnest T., Shapiro L.

Cell 134:945-955(2008) · UniProtKB (1)

Autosomal recessive woolly hair with hypotrichosis caused by a novel homozygous mutation in the P2RY5 gene.

Shimomura Y., Garzon M.C., Kristal L., Shapiro L., Christiano A.M.

Exp. Dermatol. 18:218-221(2009) · Mapped (2)

Ethnically diverse causes of Walker-Warburg syndrome (WWS): FCMD mutations are a more common cause of WWS outside of the Middle East.

Manzini M.C., Gleason D., Chang B.S., Hill R.S., Barry B.J., Partlow J.N., Poduri A., Currier S., Galvin-Parton P., Shapiro L.R. et al.

Hum. Mutat. 29:E231-41(2008) · Mapped (3)

Genome-wide linkage analysis of an autosomal recessive hypotrichosis identifies a novel P2RY5 mutation.

Petukhova L., Sousa E.C. Jr., Martinez-Mir A., Vitebsky A., Dos Santos L.G., Shapiro L., Haynes C., Gordon D., Shimomura Y., Christiano A.M.

Genomics 92:273-278(2008) · Mapped (2)

Dynamic properties of a type II cadherin adhesive domain: implications for the mechanism of strand-swapping of classical cadherins.

Miloushev V.Z., Bahna F., Ciatto C., Ahlsen G., Honig B., Shapiro L., Palmer A.G.

Structure 16:1195-1205(2008) · Mapped (6)

CD13 is a novel mediator of monocytic/endothelial cell adhesion.

Mina-Osorio P., Winnicka B., O'Conor C., Grant C.L., Vogel L.K., Rodriguez-Pinto D., Holmes K.V., Ortega E., Shapiro L.H.

J. Leukoc. Biol. 84:448-459(2008) · Mapped (11)

In DRG11 knock-out mice, trigeminal cell death is extensive and does not account for failed brainstem patterning.

Jacquin M.F., Arends J.J., Xiang C., Shapiro L.A., Ribak C.E., Chen Z.F.

J. Neurosci. 28:3577-3585(2008) · Mapped (9)

Crystal structures of beta-neurexin 1 and beta-neurexin 2 ectodomains and dynamics of splice insertion sequence 4.

Koehnke J., Jin X., Trbovic N., Katsamba P.S., Brasch J., Ahlsen G., Scheiffele P., Honig B., Palmer A.G., Shapiro L.

Structure 16:410-421(2008) · Mapped (7)

Automated, computerized, feature-based phenotype analysis of slit lamp images of the mouse lens.

Yuen J., Li Y., Shapiro L.G., Clark J.I., Arnett E., Sage E.H., Brinkley J.F.

Exp. Eye Res. 86:562-575(2008) · Mapped (6)

Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair.

Shimomura Y., Wajid M., Ishii Y., Shapiro L., Petukhova L., Gordon D., Christiano A.M.

Nat. Genet. 40:335-339(2008) · UniProtKB (2) · Mapped (1)

Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2.

Koehnke J., Jin X., Budreck E.C., Posy S., Scheiffele P., Honig B., Shapiro L.

Proc. Natl. Acad. Sci. U.S.A. 105:1873-1878(2008) · UniProtKB (1)

P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle.

Shimomura Y., Wajid M., Shapiro L., Christiano A.M.

Development 135:743-753(2008) · Mapped (10)

Structural insight into AMPK regulation: ADP comes into play.

Jin X., Townley R., Shapiro L.

Structure 15:1285-1295(2007) · Mapped (3)

Functional dissection of the C. elegans cell adhesion molecule SAX-7, a homologue of human L1.

Pocock R., Benard C.Y., Shapiro L., Hobert O.

Mol. Cell. Neurosci. 37:56-68(2008) · Mapped (4)

CD13/APN transcription is regulated by the proto-oncogene c-Maf via an atypical response element.

Mahoney K.M., Petrovic N., Schacke W., Shapiro L.H.

Gene 403:178-187(2007) · UniProtKB (2) · Mapped (10)

Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages.

Chan E.D., Kaminska A.M., Gill W., Chmura K., Feldman N.E., Bai X., Floyd C.M., Fulton K.E., Huitt G.A., Strand M.J. et al.

Scand. J. Infect. Dis. 39:690-696(2007) · Mapped (5)

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site.

Rock F.L., Mao W., Yaremchuk A., Tukalo M., Crepin T., Zhou H., Zhang Y.K., Hernandez V., Akama T., Baker S.J. et al.

Science 316:1759-1761(2007) · Mapped (2)

Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice.

Lin H.V., Kim J.Y., Pocai A., Rossetti L., Shapiro L., Scherer P.E., Accili D.

Diabetes 56:1969-1976(2007) · Mapped (18)

CD13/APN regulates endothelial invasion and filopodia formation.

Petrovic N., Schacke W., Gahagan J.R., O'Conor C.A., Winnicka B., Conway R.E., Mina-Osorio P., Shapiro L.H.

Blood 110:142-150(2007) · Mapped (4)

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.

Townley R., Shapiro L.

Science 315:1726-1729(2007) · Mapped (3)

Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon-gamma levels.

Sailer C.A., Pott G.B., Dinarello C.A., Whinney S.M., Forster J.E., Larson-Duran J.K., Landay A., Al-Harthi L., Schooley R.T., Benson C.A. et al.

J. Infect. Dis. 195:734-738(2007) · Mapped (24)

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