| Biophysical studies with AICD-47 reveal unique binding behavior characteristic of an unfolded domain. Das S., Ghosh S., Dasgupta D., Sen U., Mukhopadhyay D.
Biochem. Biophys. Res. Commun. 425:201-206(2012) · Mapped (10) |
| Functional implications of the conformational switch in AICD peptide upon binding to Grb2-SH2 domain. Das S., Raychaudhuri M., Sen U., Mukhopadhyay D.
J. Mol. Biol. 414:217-230(2011) · Mapped (5) |
| Cystathionine beta-synthase and cystathionine gamma-lyase double gene transfer ameliorate homocysteine-mediated mesangial inflammation through hydrogen sulfide generation. Sen U., Givvimani S., Abe O.A., Lederer E.D., Tyagi S.C.
Am. J. Physiol., Cell Physiol. 300:C155-63(2011) · Mapped (1) |
| Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS-/-, and iNOS-/-mice. Steed M.M., Tyagi N., Sen U., Schuschke D.A., Joshua I.G., Tyagi S.C.
Am. J. Physiol. Lung Cell Mol. Physiol. 299:L301-11(2010) · Mapped (7) |
| Cardiac specific deletion of N-methyl-d-aspartate receptor 1 ameliorates mtMMP-9 mediated autophagy/mitophagy in hyperhomocysteinemia. Tyagi N., Vacek J.C., Givvimani S., Sen U., Tyagi S.C.
J. Recept. Signal Transduct. Res. 30:78-87(2010) · Mapped (3) |
| Identification of a novel set of scaffolding residues that are instrumental for the inhibitory property of Kunitz (STI) inhibitors. Khamrui S., Majumder S., Dasgupta J., Dattagupta J.K., Sen U.
Protein Sci. 19:593-602(2010) · Mapped (1) |
| Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation. Tsai S.J., Sen U., Zhao L., Greenleaf W.B., Dasgupta J., Fiorillo E., Orru V., Bottini N., Chen X.S.
Biochemistry 48:4838-4845(2009) · UniProtKB (1) · Mapped (5) |
| Fibrinogen-induced endothelin-1 production from endothelial cells. Sen U., Tyagi N., Patibandla P.K., Dean W.L., Tyagi S.C., Roberts A.M., Lominadze D.
Am. J. Physiol., Cell Physiol. 296:C840-7(2009) · Mapped (2) |
| Nitrotyrosinylation, remodeling and endothelial-myocyte uncoupling in iNOS, cystathionine beta synthase (CBS) knockouts and iNOS/CBS double knockout mice. Kundu S., Kumar M., Sen U., Mishra P.K., Tyagi N., Metreveli N., Lominadze D., Rodriguez W., Tyagi S.C.
J. Cell. Biochem. 106:119-126(2009) · Mapped (1) |
| Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Holden L.G., Prochnow C., Chang Y.P., Bransteitter R., Chelico L., Sen U., Stevens R.C., Goodman M.F., Chen X.S.
Nature 456:121-124(2008) · UniProtKB (1) · Mapped (3) |
| Ciglitazone, a PPARgamma agonist, ameliorates diabetic nephropathy in part through homocysteine clearance. Sen U., Rodriguez W.E., Tyagi N., Kumar M., Kundu S., Tyagi S.C.
Am. J. Physiol. Endocrinol. Metab. 295:E1205-12(2008) · Mapped (1) |
| GABAA receptor agonist mitigates homocysteine-induced cerebrovascular remodeling in knockout mice. Kumar M., Tyagi N., Moshal K.S., Sen U., Pushpakumar S.B., Vacek T., Lominadze D., Tyagi S.C.
Brain Res. 1221:147-153(2008) · Mapped (6) |
| Cystathionine-beta-synthase gene transfer and 3-deazaadenosine ameliorate inflammatory response in endothelial cells. Sen U., Tyagi N., Kumar M., Moshal K.S., Rodriguez W.E., Tyagi S.C.
Am. J. Physiol., Cell Physiol. 293:C1779-87(2007) · Mapped (1) |
| Ciglitazone ameliorates homocysteine-mediated mitochondrial translocation and matrix metalloproteinase-9 activation in endothelial cells by inducing peroxisome proliferator activated receptor-gamma activity. Tyagi N., Moshal K.S., Sen U., Lominadze D., Ovechkin A.V., Tyagi S.C.
Cell. Mol. Biol. (Noisy-le-grand) 52:21-27(2006) · Mapped (9) |
| Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1. Banerjee M., Majumder P., Bhattacharyya N.P., Dattagupta J.K., Sen U.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62:1247-1250(2006) · Mapped (2) |
| 3-Deazaadenosine mitigates arterial remodeling and hypertension in hyperhomocysteinemic mice. Ovechkin A.V., Tyagi N., Sen U., Lominadze D., Steed M.M., Moshal K.S., Tyagi S.C.
Am. J. Physiol. Lung Cell Mol. Physiol. 291:L905-11(2006) · Mapped (2) |
| Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants. Dasgupta J., Khamrui S., Dattagupta J.K., Sen U.
Biochemistry 45:6783-6792(2006) · Mapped (1) |
| Purification, crystallization and preliminary X-ray structural studies of a 7.2 kDa cytotoxin isolated from the venom of Daboia russelli russelli of the Viperidae family. Choudhury S.R., Gomes A., Gomes A., Dattagupta J.K., Sen U.
Acta Crystallogr. F 62:292-294(2006) · UniProtKB (1) |
| Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1). Tsakadze N.L., Sithu S.D., Sen U., English W.R., Murphy G., D'Souza S.E.
J. Biol. Chem. 281:3157-3164(2006) · Mapped (40) |
| Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis. Khamrui S., Dasgupta J., Dattagupta J.K., Sen U.
Biochim. Biophys. Acta 1752:65-72(2005) · Mapped (2) |
| Crystal structures of HbA2 and HbE and modeling of hemoglobin delta 4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb. Sen U., Dasgupta J., Choudhury D., Datta P., Chakrabarti A., Chakrabarty S.B., Chakrabarty A., Dattagupta J.K.
Biochemistry 43:12477-12488(2004) · Mapped (11) |
| Structure of a Kunitz-type chymotrypsin from winged bean seeds at 2.95-A resolution. Dattagupta J.K., Podder A., Chakrabarti C., Sen U., Dutta S.K., Singh M.
Acta Crystallogr. D 52:521-528(1996) · UniProtKB (1) |
| Metals in the sporulation phosphorelay: manganese binding by the response regulator Spo0F. Mukhopadhyay D., Sen U., Zapf J., Varughese K.I.
Acta Crystallogr. D Biol. Crystallogr. 60:638-645(2004) · Mapped (1) |
| In silico mutations and molecular dynamics studies on a winged bean chymotrypsin inhibitor protein. Dasgupta J., Sen U., Dattagupta J.K.
Protein Eng. 16:489-496(2003) · Mapped (1) |
| Crystallization and preliminary X-ray structural studies of hemoglobin A2 and hemoglobin E, isolated from the blood samples of beta-thalassemic patients. Dasgupta J., Sen U., Choudhury D., Datta P., Chakrabarti A., Chakrabarty S.B., Chakrabarty A., Dattagupta J.K.
Biochem. Biophys. Res. Commun. 303:619-623(2003) · Mapped (8) |
