| The ERK cascade: distinct functions within various subcellular organelles. Wortzel I., Seger R.
Genes Cancer 2:195-209(2011) · UniProtKB (9) |
| Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation. Ben-Ami I., Yao Z., Naor Z., Seger R.
J. Biol. Chem. 286:31022-31031(2011) · Mapped (9) |
| Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. Plotnikov A., Chuderland D., Karamansha Y., Livnah O., Seger R.
Mol. Cell. Biol. 31:3515-3530(2011) · Mapped (15) |
| Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis. Liu L., Okada S., Kong X.F., Kreins A.Y., Cypowyj S., Abhyankar A., Toubiana J., Itan Y., Audry M., Nitschke P. et al.
J. Exp. Med. 208:1635-1648(2011) · UniProtKB (1) · Mapped (3) |
| The Ras inhibitors caveolin-1 and docking protein 1 activate peroxisome proliferator-activated receptor gamma through spatial relocalization at helix 7 of its ligand-binding domain. Burgermeister E., Friedrich T., Hitkova I., Regel I., Einwachter H., Zimmermann W., Rocken C., Perren A., Wright M.B., Schmid R.M. et al.
Mol. Cell. Biol. 31:3497-3510(2011) · Mapped (36) |
| Nuclear localization of phosphorylated ERK1 and ERK2 as markers for the progression of ovarian cancer. Amsterdam A., Shezen E., Raanan C., Schreiber L., Prus D., Slilat Y., Ben-Arie A., Seger R.
Int. J. Oncol. 39:649-656(2011) · Mapped (5) |
| CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions. Schajnovitz A., Itkin T., D'Uva G., Kalinkovich A., Golan K., Ludin A., Cohen D., Shulman Z., Avigdor A., Nagler A. et al.
Nat. Immunol. 12:391-398(2011) · Mapped (3) |
| Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. Konson A., Pradeep S., D'Acunto C.W., Seger R.
J. Biol. Chem. 286:3540-3551(2011) · Mapped (1) |
| Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction. Yao Z., Yoon S., Kalie E., Raviv Z., Seger R.
PLoS ONE 5:e12627-e12627(2010) · Mapped (11) |
| Diagnostic approach to the hyper-IgE syndromes: immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis. Schimke L.F., Sawalle-Belohradsky J., Roesler J., Wollenberg A., Rack A., Borte M., Rieber N., Cremer R., Maass E., Dopfer R. et al.
J. Allergy Clin. Immunol. 126:611-7.e1(2010) · Mapped (7) |
| BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors. Tirosh-Finkel L., Zeisel A., Brodt-Ivenshitz M., Shamai A., Yao Z., Seger R., Domany E., Tzahor E.
Development 137:2989-3000(2010) · Mapped (2) |
| Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease. Meissner F., Seger R.A., Moshous D., Fischer A., Reichenbach J., Zychlinsky A.
Blood 116:1570-1573(2010) · Mapped (8) |
| MHC class II molecules enhance Toll-like receptor mediated innate immune responses. Frei R., Steinle J., Birchler T., Loeliger S., Roduit C., Steinhoff D., Seibl R., Buchner K., Seger R., Reith W. et al.
PLoS ONE 5:e8808-e8808(2010) · Mapped (2) |
| Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Stein S., Ott M.G., Schultze-Strasser S., Jauch A., Burwinkel B., Kinner A., Schmidt M., Kramer A., Schwable J., Glimm H. et al.
Nat. Med. 16:198-204(2010) · Mapped (7) |
| Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade. Shaul Y.D., Gibor G., Plotnikov A., Seger R.
Genes Dev. 23:1779-1790(2009) · Mapped (10) |
| A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells. Dobkin-Bekman M., Naidich M., Rahamim L., Przedecki F., Almog T., Lim S., Melamed P., Liu P., Wohland T., Yao Z. et al.
Mol. Endocrinol. 23:1850-1864(2009) · Mapped (10) |
| The ERK signaling cascade--views from different subcellular compartments. Yao Z., Seger R.
BioFactors 35:407-416(2009) · UniProtKB (9) · Mapped (17) |
| Identification and characterization of a general nuclear translocation signal in signaling proteins. Chuderland D., Konson A., Seger R.
Mol. Cell 31:850-861(2008) · UniProtKB (1) · Mapped (4) |
| Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome. Renner E.D., Rylaarsdam S., Anover-Sombke S., Rack A.L., Reichenbach J., Carey J.C., Zhu Q., Jansson A.F., Barboza J., Schimke L.F. et al.
J. Allergy Clin. Immunol. 122:181-187(2008) · Mapped (7) |
| Identification of extracellular signal-regulated kinase 1/2 and p38 MAPK as regulators of human sperm motility and acrosome reaction and as predictors of poor spermatozoan quality. Almog T., Lazar S., Reiss N., Etkovitz N., Milch E., Rahamim N., Dobkin-Bekman M., Rotem R., Kalina M., Ramon J. et al.
J. Biol. Chem. 283:14479-14489(2008) · Mapped (15) |
| Distinct pathways for the involvement of WNK4 in the signaling of hypertonicity and EGF. Shaharabany M., Holtzman E.J., Mayan H., Hirschberg K., Seger R., Farfel Z.
FEBS J. 275:1631-1642(2008) · Mapped (3) |
| MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma. Burgermeister E., Seger R.
Cell Cycle 6:1539-1548(2007) · Mapped (9) |
| DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Cohen-Armon M., Visochek L., Rozensal D., Kalal A., Geistrikh I., Klein R., Bendetz-Nezer S., Yao Z., Seger R.
Mol. Cell 25:297-308(2007) · Mapped (1) |
| Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Burgermeister E., Chuderland D., Hanoch T., Meyer M., Liscovitch M., Seger R.
Mol. Cell. Biol. 27:803-817(2007) · UniProtKB (2) · Mapped (13) |
| PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation. Ben-Ami I., Freimann S., Armon L., Dantes A., Strassburger D., Friedler S., Raziel A., Seger R., Ron-El R., Amsterdam A.
Mol. Hum. Reprod. 12:593-599(2006) · Mapped (1) |
