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New ATPase regulators--p97 goes to the PUB.

Madsen L., Seeger M., Semple C.A., Hartmann-Petersen R.

Int. J. Biochem. Cell Biol. 41:2380-2388(2009) · Mapped (1)

Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome.

Bech-Otschir D., Helfrich A., Enenkel C., Consiglieri G., Seeger M., Holzhutter H.G., Dahlmann B., Kloetzel P.M.

Nat. Struct. Mol. Biol. 16:219-225(2009) · Mapped (49)

Ubxd1 is a novel co-factor of the human p97 ATPase.

Madsen L., Andersen K.M., Prag S., Moos T., Semple C.A., Seeger M., Hartmann-Petersen R.

Int. J. Biochem. Cell Biol. 40:2927-2942(2008) · UniProtKB (5)

Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease.

Schafmayer C., Volzke H., Buch S., Egberts J., Spille A., von Eberstein H., Franke A., Seeger M., Hinz S., Elsharawy A. et al.

Liver Int. 27:910-919(2007) · Mapped (12)

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.

Buch S., Schafmayer C., Voelzke H., Becker C., Franke A., von Eller-Eberstein H., Kluck C., Baessmann I., Brosch M., Lammert F. et al.

Nat. Genet. 39:995-999(2007) · UniProtKB (1) · Mapped (3)

Second acyl homoserine lactone production system in the extreme acidophile Acidithiobacillus ferrooxidans.

Rivas M., Seeger M., Jedlicki E., Holmes D.S.

Appl. Environ. Microbiol. 73:3225-3231(2007) · UniProtKB (4)

Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility.

Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L., Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M. et al.

Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006) · UniProtKB (8,591)

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

Seeger M.A., Schiefner A., Eicher T., Verrey F., Diederichs K., Pos K.M.

Science 313:1295-1298(2006) · UniProtKB (1)

Investigation of the Lith1 candidate genes ABCB11 and LXRA in human gallstone disease.

Schafmayer C., Tepel J., Franke A., Buch S., Lieb S., Seeger M., Lammert F., Kremer B., Folsch U.R., Fandrich F. et al.

Hepatology 44:650-657(2006) · Mapped (12)

The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway.

Schulze A., Standera S., Buerger E., Kikkert M., van Voorden S., Wiertz E., Koning F., Kloetzel P.-M., Seeger M.

J. Mol. Biol. 354:1021-1027(2005) · UniProtKB (4)

A Lux-like quorum sensing system in the extreme acidophile Acidithiobacillus ferrooxidans.

Rivas M., Seeger M., Holmes D.S., Jedlicki E.

Biol. Res. 38:283-297(2005) · UniProtKB (3)

Robo3 isoforms have distinct roles during zebrafish development.

Challa A.K., McWhorter M.L., Wang C., Seeger M.A., Beattie C.E.

Mech. Dev. 122:1073-1086(2005) · Mapped (14)

The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila.

Forsthoefel D.J., Liebl E.C., Kolodziej P.A., Seeger M.A.

Development 132:1983-1994(2005) · UniProtKB (1) · Mapped (14)

Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.

Stone M., Hartmann-Petersen R., Seeger M., Bech-Otschir D., Wallace M., Gordon C.

J. Mol. Biol. 344:697-706(2004) · UniProtKB (4)

A targeted gain of function screen in the embryonic CNS of Drosophila.

McGovern V.L., Pacak C.A., Sewell S.T., Turski M.L., Seeger M.A.

Mech. Dev. 120:1193-1207(2003) · UniProtKB (1) · Mapped (316)

Mosaic analysis reveals a cell-autonomous, neuronal requirement for Commissureless in the Drosophila CNS.

McGovern V.L., Seeger M.A.

Dev. Genes Evol. 213:500-504(2003) · Mapped (1)

Interactions between the secreted protein Amalgam, its transmembrane receptor Neurotactin and the Abelson tyrosine kinase affect axon pathfinding.

Liebl E.C., Rowe R.G., Forsthoefel D.J., Stammler A.L., Schmidt E.R., Turski M., Seeger M.A.

Development 130:3217-3226(2003) · Mapped (9)

Cloning of Baeyer-Villiger monooxygenases from Comamonas, Xanthobacter and Rhodococcus via PCR with highly degenerate primers.

van Beilen J.B., Mourlane F., Seeger M.A., Kovac J., Li Z., Smits T.H.M., Fritsche U., Witholt B.

Environ. Microbiol. 5:174-182(2003) · UniProtKB (7)

Ubiquitin system: JAMMing in the name of the lid.

Berndt C., Bech-Otschir D., Dubiel W., Seeger M.

Curr. Biol. 12:R815-7(2002) · Mapped (2)

The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain.

Zhao C., York A., Yang F., Forsthoefel D.J., Dave V., Fu D., Zhang D., Corado M.S., Small S., Seeger M.A. et al.

Development 129:1669-1680(2002) · Mapped (5)

Proteins containing the UBA domain are able to bind to multi-ubiquitin chains.

Wilkinson C.R.M., Seeger M., Hartmann-Petersen R., Stone M., Wallace M., Semple C., Gordon C.

Nat. Cell Biol. 3:939-943(2001) · UniProtKB (6)

Identification and characterization of roundabout orthologs in zebrafish.

Challa A.K., Beattie C.E., Seeger M.A.

Mech. Dev. 101:249-253(2001) · UniProtKB (2) · Mapped (6)

Amalgam is a ligand for the transmembrane receptor neurotactin and is required for neurotactin-mediated cell adhesion and axon fasciculation in Drosophila.

Fremion F., Darboux I., Diano M., Hipeau-Jacquotte R., Seeger M.A., Piovant M.

EMBO J. 19:4463-4472(2000) · Mapped (8)

Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding.

Liebl E.C., Forsthoefel D.J., Franco L.S., Sample S.H., Hess J.E., Cowger J.A., Chandler M.P., Shupert A.M., Seeger M.A.

Neuron 26:107-118(2000) · UniProtKB (1) · Mapped (13)

Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development.

Deng X.W., Dubiel W., Wei N., Hofmann K., Mundt K., Colicelli J., Kato J., Naumann M., Segal D., Seeger M. et al.

Trends Genet. 16:202-203(2000) · Mapped (18)

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