1 - 25 of 54 results for author:"Seabra M.C." in Literature citations
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| Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression. Bobrie A., Krumeich S., Reyal F., Recchi C., Moita L.F., Seabra M.C., Ostrowski M., Thery C. Cancer Res. 72:4920-4930(2012) · Mapped (4) |
| Myosin Va acts in concert with Rab27a and MyRIP to regulate acute von-Willebrand factor release from endothelial cells. Rojo Pulido I., Nightingale T.D., Darchen F., Seabra M.C., Cutler D.F., Gerke V. Traffic 12:1371-1382(2011) · Mapped (15) |
| Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland. Chiang L., Ngo J., Schechter J.E., Karvar S., Tolmachova T., Seabra M.C., Hume A.N., Hamm-Alvarez S.F. Am. J. Physiol., Cell Physiol. 301:C507-21(2011) · Mapped (6) |
| The gunmetal mouse reveals Rab geranylgeranyl transferase to be the major molecular target of phosphonocarboxylate analogues of bisphosphonates. Coxon F.P., Taylor A., Stewart C.A., Baron R., Seabra M.C., Ebetino F.H., Rogers M.J. Bone 49:111-121(2011) · Mapped (3) |
| Loss of Rab27 function results in abnormal lung epithelium structure in mice. Bolasco G., Tracey-White D.C., Tolmachova T., Thorley A.J., Tetley T.D., Seabra M.C., Hume A.N. Am. J. Physiol., Cell Physiol. 300:C466-76(2011) · Mapped (6) |
| PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils. Anderson K.E., Chessa T.A., Davidson K., Henderson R.B., Walker S., Tolmachova T., Grys K., Rausch O., Seabra M.C., Tybulewicz V.L. et al. Blood 116:4978-4989(2010) · Mapped (8) |
| Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. Hendrix A., Maynard D., Pauwels P., Braems G., Denys H., Van den Broecke R., Lambert J., Van Belle S., Cocquyt V., Gespach C. et al. J. Natl. Cancer Inst. 102:866-880(2010) · Mapped (1) |
| Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia. Tolmachova T., Wavre-Shapton S.T., Barnard A.R., MacLaren R.E., Futter C.E., Seabra M.C. Invest. Ophthalmol. Vis. Sci. 51:4913-4920(2010) · Mapped (5) |
| Armus is a Rac1 effector that inactivates Rab7 and regulates E-cadherin degradation. Frasa M.A., Maximiano F.C., Smolarczyk K., Francis R.E., Betson M.E., Lozano E., Goldenring J., Seabra M.C., Rak A., Ahmadian M.R. et al. |
| Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms. Johnson J.L., Brzezinska A.A., Tolmachova T., Munafo D.B., Ellis B.A., Seabra M.C., Hong H., Catz S.D. Traffic 11:533-547(2010) · Mapped (4) |
| Rab27a and Rab27b control different steps of the exosome secretion pathway. Ostrowski M., Carmo N.B., Krumeich S., Fanget I., Raposo G., Savina A., Moita C.F., Schauer K., Hume A.N., Freitas R.P. et al. Nat. Cell Biol. 12:19-30; sup pp 2010:1-13(2010) |
| Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport. Ramalho J.S., Lopes V.S., Tarafder A.K., Seabra M.C., Hume A.N. Pigment Cell Melanoma Res 22:461-473(2009) · Mapped (3) |
| Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. Nightingale T.D., Pattni K., Hume A.N., Seabra M.C., Cutler D.F. Blood 113:5010-5018(2009) · Mapped (5) |
| Single choroideremia gene in nonmammalian vertebrates explains early embryonic lethality of the zebrafish model of choroideremia. Moosajee M., Tulloch M., Baron R.A., Gregory-Evans C.Y., Pereira-Leal J.B., Seabra M.C. Invest. Ophthalmol. Vis. Sci. 50:3009-3016(2009) · Mapped (4) |
| Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease. Moosajee M., Gregory-Evans K., Ellis C.D., Seabra M.C., Gregory-Evans C.Y. Hum. Mol. Genet. 17:3987-4000(2008) · Mapped (17) |
| Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes. Figueiredo A.C., Wasmeier C., Tarafder A.K., Ramalho J.S., Baron R.A., Seabra M.C. J. Biol. Chem. 283:23209-23216(2008) · Mapped (10) |
| Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate. Baron R.A., Seabra M.C. Biochem. J. 415:67-75(2008) · UniProtKB (3) |
| Rab27a and MyoVa are the primary Mlph interactors regulating melanosome transport in melanocytes. Hume A.N., Ushakov D.S., Tarafder A.K., Ferenczi M.A., Seabra M.C. J. Cell. Sci. 120:3111-3122(2007) · Mapped (14) |
| Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis. Lopes V.S., Wasmeier C., Seabra M.C., Futter C.E. Mol. Biol. Cell 18:3914-3927(2007) · Mapped (2) |
| Rab27b regulates mast cell granule dynamics and secretion. Mizuno K., Tolmachova T., Ushakov D.S., Romao M., Abrink M., Ferenczi M.A., Raposo G., Seabra M.C. Traffic 8:883-892(2007) · Mapped (4) |
| Rab27b regulates number and secretion of platelet dense granules. Tolmachova T., Abrink M., Futter C.E., Authi K.S., Seabra M.C. Proc. Natl. Acad. Sci. U.S.A. 104:5872-5877(2007) · Mapped (6) |
| Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Jancic C., Savina A., Wasmeier C., Tolmachova T., El-Benna J., Dang P.M., Pascolo S., Gougerot-Pocidalo M.A., Raposo G., Seabra M.C. et al. Nat. Cell Biol. 9:367-378(2007) · Mapped (2) |
| Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation. Leung K.F., Baron R., Ali B.R., Magee A.I., Seabra M.C. J. Biol. Chem. 282:1487-1497(2007) · UniProtKB (1) |
| Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. Wasmeier C., Romao M., Plowright L., Bennett D.C., Raposo G., Seabra M.C. J. Cell Biol. 175:271-281(2006) · Mapped (5) |
| A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes. Hume A.N., Tarafder A.K., Ramalho J.S., Sviderskaya E.V., Seabra M.C. Mol. Biol. Cell 17:4720-4735(2006) · Mapped (7) |