| PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. Lim Y., Lim S.-T., Tomar A., Gardel M., Bernard-Trifilo J.A., Chen X.L., Uryu S.A., Canete-Soler R., Zhai J., Lin H. et al.
J. Cell Biol. 180:187-203(2008) · UniProtKB (1) · Mapped (16) |
| Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1. Zhai J., Lin H., Julien J.P., Schlaepfer W.W.
Hum. Mol. Genet. 16:3103-3116(2007) · Mapped (4) |
| RNA-binding protein is involved in aggregation of light neurofilament protein and is implicated in the pathogenesis of motor neuron degeneration. Lin H., Zhai J., Schlaepfer W.W.
Hum. Mol. Genet. 14:3643-3659(2005) · UniProtKB (2) · Mapped (10) |
| HoxB2 binds mutant SOD1 and is altered in transgenic model of ALS. Zhai J., Lin H., Canete-Soler R., Schlaepfer W.W.
Hum. Mol. Genet. 14:2629-2640(2005) · Mapped (2) |
| Cytoplasmic retention sites in p190RhoGEF confer anti-apoptotic activity to an EGFP-tagged protein. Wu J., Zhai J., Lin H., Nie Z., Ge W.-W., Garcia-Bermejo L., Muschel R.J., Schlaepfer W.W., Canete-Soler R.
Brain Res. Mol. Brain Res. 117:27-38(2003) · UniProtKB (4) |
| Direct interaction of focal adhesion kinase with p190RhoGEF. Zhai J., Lin H., Nie Z., Wu J., Canete-Soler R., Schlaepfer W.W., Schlaepfer D.D.
J. Biol. Chem. 278:24865-24873(2003) · UniProtKB (4) · Mapped (3) |
| Binding of p190RhoGEF to a destabilizing element on the light neurofilament mRNA is competed by BC1 RNA. Ge W.-W., Wu J., Zhai J., Nie Z., Lin H., Schlaepfer W.W., Canete-Soler R.
J. Biol. Chem. 277:42701-42705(2002) · UniProtKB (1) |
| Identification of a novel interaction of 14-3-3 with p190RhoGEF. Zhai J., Lin H., Shamim M., Schlaepfer W.W., Canete-Soler R.
J. Biol. Chem. 276:41318-41324(2001) · UniProtKB (3) · Mapped (1) |
| p190RhoGEF Binds to a destabilizing element in the 3' untranslated region of light neurofilament subunit mRNA and alters the stability of the transcript. Canete-Soler R., Wu J., Zhai J., Shamim M., Schlaepfer W.W.
J. Biol. Chem. 276:32046-32050(2001) · UniProtKB (2) |
| Mutation in neurofilament transgene implicates RNA processing in the pathogenesis of neurodegenerative disease. Canete-Soler R., Silberg D.G., Gershon M.D., Schlaepfer W.W.
J. Neurosci. 19:1273-1283(1999) · Mapped (2) |
| In vitro activation of the mouse mid-sized neurofilament gene by an NF-1-like transcription factor. Schwartz M.L., Hua Y., Schlaepfer W.W.
Brain Res. Mol. Brain Res. 48:305-314(1997) · Mapped (2) |
| Methylation and expression of neurofilament genes in tissues and in cell lines of the mouse. Bruce J., Schwartz M.L., Shneidman P.S., Schlaepfer W.W.
Brain Res. Mol. Brain Res. 17:269-278(1993) · Mapped (6) |
| Brain-specific enhancement of the mouse neurofilament heavy gene promoter in vitro. Schwartz M.L., Katagi C., Bruce J., Schlaepfer W.W.
J. Biol. Chem. 269:13444-13450(1994) · Mapped (2) |
| Deletion of 3'-untranslated region alters the level of mRNA expression of a neurofilament light subunit transgene. Schwartz M.L., Bruce J., Shneidman P.S., Schlaepfer W.W.
J. Biol. Chem. 270:26364-26369(1995) · Mapped (2) |
| The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. Myers M.W., Lazzarini R.A., Lee V.M.-Y., Schlaepfer W.W., Nelson D.L.
EMBO J. 6:1617-1626(1987) · UniProtKB (1) |
| Two-stage autolysis of the catalytic subunit initiates activation of calpain I. Zimmerman U.J., Schlaepfer W.W.
Biochim. Biophys. Acta 1078:192-198(1991) · UniProtKB (1) |
| Negative regulatory regions are present upstream in the three mouse neurofilament genes. Shneidman P.S., Bruce J., Schwartz M.L., Schlaepfer W.W.
Brain Res. Mol. Brain Res. 13:127-138(1992) · Mapped (6) |