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A survey of integral alpha-helical membrane proteins.

Kelly L., Pieper U., Eswar N., Hays F.A., Li M., Roe-Zurz Z., Kroetz D.L., Giacomini K.M., Stroud R.M., Sali A.

J. Struct. Funct. Genomics 0:0-0(2009) · Mapped (3)

Global motions of the nuclear pore complex: insights from elastic network models.

Lezon T.R., Sali A., Bahar I.

PLoS Comput. Biol. 5:e1000496-e1000496(2009) · Mapped (9)

Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor.

DeGrasse J.A., DuBois K.N., Devos D., Siegel T.N., Sali A., Field M.C., Rout M.P., Chait B.T.

Mol. Cell Proteomics 8:2119-2130(2009) · Mapped (15)

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer.

Wu B., Moulton H.M., Iversen P.L., Jiang J., Li J., Li J., Spurney C.F., Sali A., Guerron A.D., Nagaraju K. et al.

Proc. Natl. Acad. Sci. U.S.A. 105:14814-14819(2008) · Mapped (7)

Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90.

Krukenberg K.A., Forster F., Rice L.M., Sali A., Agard D.A.

Structure 16:755-765(2008) · Mapped (1)

Structure of the mammalian 80S ribosome at 8.7 A resolution.

Chandramouli P., Topf M., Menetret J.F., Eswar N., Cannone J.J., Gutell R.R., Sali A., Akey C.W.

Structure 16:535-548(2008) · Mapped (44)

Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.

Anderson C.M., Korkin D., Smith D.L., Makovets S., Seidel J.J., Sali A., Blackburn E.H.

Genes Dev. 22:854-859(2008) · Mapped (8)

Structural genomics of protein phosphatases.

Almo S.C., Bonanno J.B., Sauder J.M., Emtage S., Dilorenzo T.P., Malashkevich V., Wasserman S.R., Swaminathan S., Eswaramoorthy S., Agarwal R. et al.

J. Struct. Funct. Genomics 8:121-140(2007) · UniProtKB (1) · Mapped (19)

The molecular architecture of the nuclear pore complex.

Alber F., Dokudovskaya S., Veenhoff L.M., Zhang W., Kipper J., Devos D., Suprapto A., Karni-Schmidt O., Williams R., Chait B.T. et al.

Nature 450:695-701(2007) · Mapped (30)

Determining the architectures of macromolecular assemblies.

Alber F., Dokudovskaya S., Veenhoff L.M., Zhang W., Kipper J., Devos D., Suprapto A., Karni-Schmidt O., Williams R., Chait B.T. et al.

Nature 450:683-694(2007) · Mapped (30)

Crystallographic conformers of actin in a biologically active bundle of filaments.

Cong Y., Topf M., Sali A., Matsudaira P., Dougherty M., Chiu W., Schmid M.F.

J. Mol. Biol. 375:331-336(2008) · Mapped (1)

The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family.

Wang S.X., Pandey K.C., Scharfstein J., Whisstock J., Huang R.K., Jacobelli J., Fletterick R.J., Rosenthal P.J., Abrahamson M., Brinen L.S. et al.

Structure 15:535-543(2007) · Mapped (2)

Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.

Carvalho M.A., Marsillac S.M., Karchin R., Manoukian S., Grist S., Swaby R.F., Urmenyi T.P., Rondinelli E., Silva R., Gayol L. et al.

Cancer Res. 67:1494-1501(2007) · Mapped (33)

Simple fold composition and modular architecture of the nuclear pore complex.

Devos D., Dokudovskaya S., Williams R., Alber F., Eswar N., Chait B.T., Rout M.P., Sali A.

Proc. Natl. Acad. Sci. U.S.A. 103:2172-2177(2006) · Mapped (29)

The C-type lectin fold as an evolutionary solution for massive sequence variation.

McMahon S.A., Miller J.L., Lawton J.A., Kerkow D.E., Hodes A., Marti-Renom M.A., Doulatov S., Narayanan E., Sali A., Miller J.F. et al.

Nat. Struct. Mol. Biol. 12:886-892(2005) · Mapped (1)

Multiple cathepsin B isoforms in schistosomula of Trichobilharzia regenti: identification, characterisation and putative role in migration and nutrition.

Dvorak J., Delcroix M., Rossi A., Vopalensky V., Pospisek M., Sedinova M., Mikes L., Sajid M., Sali A., McKerrow J.H. et al.

Int. J. Parasitol. 35:895-910(2005) · UniProtKB (6)

Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22.

Yasuda S., Morokawa N., Wong G.W., Rossi A., Madhusudhan M.S., Sali A., Askew Y.S., Adachi R., Silverman G.A., Krilis S.A. et al.

Blood 105:3893-3901(2005) · Mapped (1)

Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression.

Johnson K., Goding J., Van Etten D., Sali A., Hu S.I., Farley D., Krug H., Hessle L., Millan J.L., Terkeltaub R.

J. Bone Miner. Res. 18:994-1004(2003) · Mapped (5)

Study of the structural dynamics of the E. coli 70S ribosome using real-space refinement.

Gao H., Sengupta J., Valle M., Korostelev A., Eswar N., Stagg S.M., Van Roey P., Agrawal R.K., Harvey S.C., Sali A. et al.

Cell 113:789-801(2003) · UniProtKB (44) · Mapped (57)

Use of single point mutations in domain I of beta 2-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies.

Iverson G.M., Reddel S., Victoria E.J., Cockerill K.A., Wang Y.X., Marti-Renom M.A., Sali A., Marquis D.M., Krilis S.A., Linnik M.D.

J. Immunol. 169:7097-7103(2002) · Mapped (2)

Structural basis of allotypes of ecto-nucleotide pyrophosphatase/phosphodiesterase (plasma cell membrane glycoprotein PC-1) in the mouse and rat, and analysis of allele-specific xenogeneic antibodies.

Banakh I., Sali A., Dubljevic V., Grobben B., Slegers H., Goding J.W.

Eur. J. Immunogenet. 29:307-313(2002) · UniProtKB (2) · Mapped (4)

Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization.

Hessle L., Johnson K.A., Anderson H.C., Narisawa S., Sali A., Goding J.W., Terkeltaub R., Millan J.L.

Proc. Natl. Acad. Sci. U.S.A. 99:9445-9449(2002) · Mapped (11)

RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function.

Yang Y., Li L., Wong G.W., Krilis S.A., Madhusudhan M.S., Sali A., Stevens R.L.

J. Biol. Chem. 277:25756-25774(2002) · UniProtKB (2) · Mapped (6)

Structural genomics: a pipeline for providing structures for the biologist.

Chance M.R., Bresnick A.R., Burley S.K., Jiang J.-S., Lima C.D., Sali A., Almo S.C., Bonanno J.B., Buglino J.A., Boulton S. et al.

Protein Sci. 11:723-738(2002) · UniProtKB (1)

MODBASE, a database of annotated comparative protein structure models.

Pieper U., Eswar N., Stuart A.C., Ilyin V.A., Sali A.

Nucleic Acids Res. 30:255-259(2002) · Mapped (5)

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