1 - 25 of 132 results for author:"Sacchettini J.C." in Literature citations
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| Structure of the apo form of Bacillus stearothermophilus phosphofructokinase. Mosser R., Reddy M.C., Bruning J.B., Sacchettini J.C., Reinhart G.D. Biochemistry 51:769-775(2012) · Mapped (1) |
| Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Gokulan K., Aggarwal A., Shipman L., Besra G.S., Sacchettini J.C. Acta Crystallogr. D Biol. Crystallogr. 67:657-669(2011) · UniProtKB (1) · Mapped (1) |
| Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Dias M.V., Snee W.C., Bromfield K.M., Payne R.J., Palaninathan S.K., Ciulli A., Howard N.I., Abell C., Sacchettini J.C., Blundell T.L. Biochem. J. 436:729-739(2011) · Mapped (1) |
| Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. Molle V., Gulten G., Vilcheze C., Veyron-Churlet R., Zanella-Cleon I., Sacchettini J.C., Jacobs W.R. Jr., Kremer L. Mol. Microbiol. 78:1591-1605(2010) · Mapped (1) |
| Structure of the Mycobacterium tuberculosis D-alanine:D-alanine ligase, a target of the antituberculosis drug D-cycloserine. Bruning J.B., Murillo A.C., Chacon O., Barletta R.G., Sacchettini J.C. Antimicrob. Agents Chemother. 55:291-301(2011) · Mapped (1) |
| Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Drage M.G., Tsai H.C., Pecora N.D., Cheng T.Y., Arida A.R., Shukla S., Rojas R.E., Seshadri C., Moody D.B., Boom W.H. et al. Nat. Struct. Mol. Biol. 17:1088-1095(2010) · Mapped (1) |
| Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase. Dey S., Lane J.M., Lee R.E., Rubin E.J., Sacchettini J.C. Biochemistry 49:6746-6760(2010) · UniProtKB (3) |
| Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein. Shetty N.D., Reddy M.C., Palaninathan S.K., Owen J.L., Sacchettini J.C. Protein Sci. 19:1513-1524(2010) · Mapped (1) |
| Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway. Kalscheuer R., Syson K., Veeraraghavan U., Weinrick B., Biermann K.E., Liu Z., Sacchettini J.C., Besra G., Bornemann S., Jacobs W.R. Jr. Nat. Chem. Biol. 6:376-384(2010) · UniProtKB (7) |
| Regulation of a muralytic enzyme by dynamic membrane topology. Sun Q., Kuty G.F., Arockiasamy A., Xu M., Young R., Sacchettini J.C. Nat. Struct. Mol. Biol. 16:1192-1194(2009) · Mapped (1) |
| Structural insights into the mechanism of the allosteric transitions of Mycobacterium tuberculosis cAMP receptor protein. Reddy M.C., Palaninathan S.K., Bruning J.B., Thurman C., Smith D., Sacchettini J.C. J. Biol. Chem. 284:36581-36591(2009) · UniProtKB (1) |
| Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis. Palaninathan S.K., Mohamedmohaideen N.N., Orlandini E., Ortore G., Nencetti S., Lapucci A., Rossello A., Freundlich J.S., Sacchettini J.C. PLoS ONE 4:e6290-e6290(2009) · Mapped (1) |
| Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis. Barkan D., Liu Z., Sacchettini J.C., Glickman M.S. Chem. Biol. 16:499-509(2009) · UniProtKB (1) |
| Triclosan derivatives: towards potent inhibitors of drug-sensitive and drug-resistant Mycobacterium tuberculosis. Freundlich J.S., Wang F., Vilcheze C., Gulten G., Langley R., Schiehser G.A., Jacobus D.P., Jacobs W.R. Jr., Sacchettini J.C. ChemMedChem 4:241-248(2009) · Mapped (1) |
| Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors. Reddy M.C., Kuppan G., Shetty N.D., Owen J.L., Ioerger T.R., Sacchettini J.C. Protein Sci. 17:2134-2144(2008) · UniProtKB (1) · Mapped (1) |
| Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening. Cho Y., Ioerger T.R., Sacchettini J.C. J. Med. Chem. 51:5984-5992(2008) |
| Structural insight into pH-induced conformational changes within the native human transthyretin tetramer. Palaninathan S.K., Mohamedmohaideen N.N., Snee W.C., Kelly J.W., Sacchettini J.C. J. Mol. Biol. 382:1157-1167(2008) · UniProtKB (1) · Mapped (5) |
| Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis. Vilcheze C., Av-Gay Y., Attarian R., Liu Z., Hazbon M.H., Colangeli R., Chen B., Liu W., Alland D., Sacchettini J.C. et al. Mol. Microbiol. 69:1316-1329(2008) |
| Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase. Dey S., Burton R.L., Grant G.A., Sacchettini J.C. Biochemistry 47:8271-8282(2008) · Mapped (12) |
| The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Javid-Majd F., Yang D., Ioerger T.R., Sacchettini J.C. Acta Crystallogr. D Biol. Crystallogr. 64:627-635(2008) · Mapped (1) |
| Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis. Mohamedmohaideen N.N., Palaninathan S.K., Morin P.M., Williams B.J., Braunstein M., Tichy S.E., Locker J., Russell D.H., Jacobs W.R. Jr., Sacchettini J.C. Biochemistry 47:6092-6102(2008) · UniProtKB (1) · Mapped (4) |
| A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase. Chinnaswamy S., Yarbrough I., Palaninathan S., Kumar C.T., Vijayaraghavan V., Demeler B., Lemon S.M., Sacchettini J.C., Kao C.C. J. Biol. Chem. 283:20535-20546(2008) · Mapped (154) |
| Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria. Alahari A., Trivelli X., Guerardel Y., Dover L.G., Besra G.S., Sacchettini J.C., Reynolds R.C., Coxon G.D., Kremer L. PLoS ONE 2:E1343-E1343(2007) · UniProtKB (3) |
| Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15. Bhardwaj K., Palaninathan S., Alcantara J.M., Yi L.L., Guarino L., Sacchettini J.C., Kao C.C. J. Biol. Chem. 283:3655-3664(2008) · Mapped (1) |
| Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response. Reddy M.C., Gokulan K., Jacobs W.R. Jr., Ioerger T.R., Sacchettini J.C. Protein Sci. 17:159-170(2008) · UniProtKB (1) |