| Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly. Cargnello M., Tcherkezian J., Dorn J.F., Huttlin E.L., Maddox P.S., Gygi S.P., Roux P.P.
Mol. Cell. Biol. 32:4572-4584(2012) · Mapped (11) |
| Regulation of karyopherin alpha1 and nuclear import by mammalian target of rapamycin. Fielhaber J.A., Tan J., Joung K.B., Attias O., Huegel S., Bader M., Roux P.P., Kristof A.S.
J. Biol. Chem. 287:14325-14335(2012) · Mapped (12) |
| ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1). Carriere A., Romeo Y., Acosta-Jaquez H.A., Moreau J., Bonneil E., Thibault P., Fingar D.C., Roux P.P.
J. Biol. Chem. 286:567-577(2011) · Mapped (21) |
| mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. Oh W.J., Wu C.C., Kim S.J., Facchinetti V., Julien L.A., Finlan M., Roux P.P., Su B., Jacinto E.
EMBO J. 29:3939-3951(2010) · UniProtKB (1) · Mapped (16) |
| Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Tcherkezian J., Brittis P.A., Thomas F., Roux P.P., Flanagan J.G.
Cell 141:632-644(2010) · Mapped (2) |
| mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. Julien L.A., Carriere A., Moreau J., Roux P.P.
Mol. Cell. Biol. 30:908-921(2010) · UniProtKB (2) · Mapped (21) |
| Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation. Foster K.G., Acosta-Jaquez H.A., Romeo Y., Ekim B., Soliman G.A., Carriere A., Roux P.P., Ballif B.A., Fingar D.C.
J. Biol. Chem. 285:80-94(2010) · UniProtKB (1) · Mapped (19) |
| Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation. Carriere A., Cargnello M., Julien L.A., Gao H., Bonneil E., Thibault P., Roux P.P.
Curr. Biol. 18:1269-1277(2008) · UniProtKB (3) · Mapped (11) |
| The RSK factors of activating the Ras/MAPK signaling cascade. Carriere A., Ray H., Blenis J., Roux P.P.
Front. Biosci. 13:4258-4275(2008) · UniProtKB (2) |
| RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. Roux P.P., Shahbazian D., Vu H., Holz M.K., Cohen M.S., Taunton J., Sonenberg N., Blenis J.
J. Biol. Chem. 282:14056-14064(2007) · UniProtKB (4) |
| The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. Shahbazian D., Roux P.P., Mieulet V., Cohen M.S., Raught B., Taunton J., Hershey J.W., Blenis J., Pende M., Sonenberg N.
EMBO J. 25:2781-2791(2006) · UniProtKB (2) · Mapped (16) |
| The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling. Anjum R., Roux P.P., Ballif B.A., Gygi S.P., Blenis J.
Curr. Biol. 15:1762-1767(2005) · UniProtKB (3) · Mapped (6) |
| Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors. Ballif B.A., Roux P.P., Gerber S.A., MacKeigan J.P., Blenis J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 102:667-672(2005) · Mapped (2) |
| Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. Roux P.P., Ballif B.A., Anjum R., Gygi S.P., Blenis J.
Proc. Natl. Acad. Sci. U.S.A. 101:13489-13494(2004) · UniProtKB (2) |
| Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity. Roux P.P., Richards S.A., Blenis J.
Mol. Cell. Biol. 23:4796-4804(2003) · UniProtKB (1) |
| NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor dependent apoptosis. Salehi A.H., Roux P.P., Kubu C.J., Zeindler C., Bhakar A., Tannis L.-L., Verdi J.M., Barker P.A.
Neuron 27:279-288(2000) · UniProtKB (2) · Mapped (1) |
