| Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. Zhang Y., Chen Y.C., Krummel M.F., Rosen S.D.
J. Immunol. 189:3914-3924(2012) · Mapped (3) |
| Heparan sulfate sulfatase SULF2 regulates PDGFRalpha signaling and growth in human and mouse malignant glioma. Phillips J.J., Huillard E., Robinson A.E., Ward A., Lum D.H., Polley M.Y., Rosen S.D., Rowitch D.H., Werb Z.
J. Clin. Invest. 122:911-922(2012) · Mapped (16) |
| Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs. Arata-Kawai H., Singer M.S., Bistrup A., Zante A., Wang Y.Q., Ito Y., Bao X., Hemmerich S., Fukuda M., Rosen S.D.
Am. J. Pathol. 178:423-433(2011) · Mapped (14) |
| Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis. Lemjabbar-Alaoui H., van Zante A., Singer M.S., Xue Q., Wang Y.Q., Tsay D., He B., Jablons D.M., Rosen S.D.
Oncogene 29:635-646(2010) · Mapped (6) |
| Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88. Hossain M.M., Hosono-Fukao T., Tang R., Sugaya N., van Kuppevelt T.H., Jenniskens G.J., Kimata K., Rosen S.D., Uchimura K.
Glycobiology 20:175-186(2010) |
| Functional consequences of the subdomain organization of the sulfs. Tang R., Rosen S.D.
J. Biol. Chem. 284:21505-21514(2009) · Mapped (11) |
| Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins. Kerr S.C., Fieger C.B., Snapp K.R., Rosen S.D.
J. Immunol. 181:1480-1490(2008) · UniProtKB (4) |
| Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. Kanda H., Newton R., Klein R., Morita Y., Gunn M.D., Rosen S.D.
Nat. Immunol. 9:415-423(2008) · Mapped (6) |
| Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs. Veerman K.M., Williams M.J., Uchimura K., Singer M.S., Merzaban J.S., Naus S., Carlow D.A., Owen P., Rivera-Nieves J., Rosen S.D. et al.
Nat. Immunol. 8:532-539(2007) · Mapped (15) |
| Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2. Lum D.H., Tan J., Rosen S.D., Werb Z.
Mol. Cell. Biol. 27:678-688(2007) · Mapped (14) |
| Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis. Yang J., Rosen S.D., Bendele P., Hemmerich S.
BMC Immunol. 7:12-12(2006) · Mapped (2) |
| HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. Uchimura K., Morimoto-Tomita M., Bistrup A., Li J., Lyon M., Gallagher J., Werb Z., Rosen S.D.
BMC Biochem. 7:2-2(2006) · Mapped (6) |
| Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Morimoto-Tomita M., Uchimura K., Bistrup A., Lum D.H., Egeblad M., Boudreau N., Werb Z., Rosen S.D.
Neoplasia 7:1001-1010(2005) · Mapped (6) |
| A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Uchimura K., Gauguet J.M., Singer M.S., Tsay D., Kannagi R., Muramatsu T., von Andrian U.H., Rosen S.D.
Nat. Immunol. 6:1105-1113(2005) · Mapped (3) |
| Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes. Gauguet J.M., Rosen S.D., Marth J.D., von Andrian U.H.
Blood 104:4104-4112(2004) · Mapped (9) |
| N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing. Uchimura K., Kadomatsu K., El-Fasakhany F.M., Singer M.S., Izawa M., Kannagi R., Takeda N., Rosen S.D., Muramatsu T.
J. Biol. Chem. 279:35001-35008(2004) · UniProtKB (1) · Mapped (1) |
| Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope. Bistrup A., Tsay D., Shenoy P., Singer M.S., Bangia N., Luther S.A., Cyster J.G., Ruddle N.H., Rosen S.D.
Am. J. Pathol. 164:1635-1644(2004) · UniProtKB (1) · Mapped (4) |
| Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouse. van Zante A., Gauguet J.-M., Bistrup A., Tsay D., von Andrian U.H., Rosen S.D.
J. Exp. Med. 198:1289-1300(2003) · UniProtKB (1) · Mapped (15) |
| Endoglycan, a member of the CD34 family, functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x. Fieger C.B., Sassetti C.M., Rosen S.D.
J. Biol. Chem. 278:27390-27398(2003) · UniProtKB (1) |
| Activities and expression pattern of the carbohydrate sulfotransferase GlcNAc6ST-3 (I-GlcNAc6ST): functional implications. Lee J.K., Bistrup A., van Zante A., Rosen S.D.
Glycobiology 13:245-254(2003) · UniProtKB (1) |
| Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface. Genbacev O.D., Prakobphol A., Foulk R.A., Krtolica A.R., Ilic D., Singer M.S., Yang Z.Q., Kiessling L.L., Rosen S.D., Fisher S.J.
Science 299:405-408(2003) · Mapped (4) |
| Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. Morimoto-Tomita M., Uchimura K., Werb Z., Hemmerich S., Rosen S.D.
J. Biol. Chem. 277:49175-49185(2002) · UniProtKB (4) · Mapped (10) |
| Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes. Hemmerich S., Bistrup A., Singer M.S., van Zante A., Lee J.K., Tsay D., Peters M., Carminati J.L., Brennan T.J., Carver-Moore K. et al.
Immunity 15:237-247(2001) · UniProtKB (1) |
| Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family. Hemmerich S., Lee J.K., Bhakta S., Bistrup A., Ruddle N.R., Rosen S.D.
Glycobiology 11:75-87(2001) · UniProtKB (3) · Mapped (8) |
| Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5). Bhakta S., Bartes A., Bowman K.G., Kao W.-M., Polsky I., Lee J.-K., Cook B.N., Bruehl R.E., Rosen S.D., Bertozzi C.R. et al.
J. Biol. Chem. 275:40226-40234(2000) · UniProtKB (2) |
