| Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay. Ouimet T., Orng S.V., Poras H., Gagnidze K., Devi L.A., Fournie-Zaluski M.C., Roques B.P.
J. Biol. Chem. 285:34390-34400(2010) · Mapped (15) |
| Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats. Padia S.H., Howell N.L., Kemp B.A., Fournie-Zaluski M.C., Roques B.P., Carey R.M.
Hypertension 55:474-480(2010) · Mapped (3) |
| Involvement of enkephalins in the inhibition of osteosarcoma-induced thermal hyperalgesia evoked by the blockade of peripheral P2X3 receptors. Gonzalez-Rodriguez S., Pevida M., Roques B.P., Fournie-Zaluski M.C., Hidalgo A., Menendez L., Baamonde A.
Neurosci. Lett. 465:285-289(2009) · Mapped (2) |
| Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250. Fournie-Zaluski M.C., Poras H., Roques B.P., Nakajima Y., Ito K., Yoshimoto T.
Acta Crystallogr. D 65:814-822(2009) · UniProtKB (1) |
| Structure-based dissection of the active site chemistry of leukotriene A4 hydrolase: implications for M1 aminopeptidases and inhibitor design. Tholander F., Muroya A., Roques B.P., Fournie-Zaluski M.C., Thunnissen M.M., Haeggstrom J.Z.
Chem. Biol. 15:920-929(2008) · UniProtKB (1) |
| How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription. Bourbigot S., Ramalanjaona N., Boudier C., Salgado G.F., Roques B.P., Mely Y., Bouaziz S., Morellet N.
J. Mol. Biol. 383:1112-1128(2008) · Mapped (1) |
| Human brain aminopeptidase A: biochemical properties and distribution in brain nuclei. de Mota N., Iturrioz X., Claperon C., Bodineau L., Fassot C., Roques B.P., Palkovits M., Llorens-Cortes C.
J. Neurochem. 106:416-428(2008) · Mapped (13) |
| Insights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers. Gao L., Balakrishnan M., Roques B.P., Bambara R.A.
J. Biol. Chem. 282:6222-6231(2007) · Mapped (1) |
| CB1 receptor knockout mice show similar behavioral modifications to wild-type mice when enkephalin catabolism is inhibited. Jardinaud F., Crete D., Canestrelli C., Ledent C., Roques B.P., Noble F.
Brain Res. 1063:77-83(2005) · Mapped (8) |
| Synthetic Vpr protein activates activator protein-1, c-Jun N-terminal kinase, and NF-kappaB and stimulates HIV-1 transcription in promonocytic cells and primary macrophages. Varin A., Decrion A.Z., Sabbah E., Quivy V., Sire J., Van Lint C., Roques B.P., Aggarwal B.B., Herbein G.
J. Biol. Chem. 280:42557-42567(2005) · Mapped (9) |
| Structure of the zinc finger domain encompassing residues 13-51 of the nucleocapsid protein from simian immunodeficiency virus. Morellet N., Meudal H., Bouaziz S., Roques B.P.
Biochem. J. 393:725-732(2006) · UniProtKB (1) |
| Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors. Nieto M.M., Guen S.L., Kieffer B.L., Roques B.P., Noble F.
Neuroscience 135:305-313(2005) · Mapped (23) |
| Helical structure determined by NMR of the HIV-1 (345-392)Gag sequence, surrounding p2: implications for particle assembly and RNA packaging. Morellet N., Druillennec S., Lenoir C., Bouaziz S., Roques B.P.
Protein Sci. 14:375-386(2005) · Mapped (3) |
| The C-terminal domain of the HIV-1 regulatory protein Vpr adopts an antiparallel dimeric structure in solution via its leucine-zipper-like domain. Bourbigot S., Beltz H., Denis J., Morellet N., Roques B.P., Mely Y., Bouaziz S.
Biochem. J. 387:333-341(2005) · Mapped (1) |
| Structural analysis of neprilysin with various specific and potent inhibitors. Oefner C., Roques B.P., Fournie-Zaluski M.-C., Dale G.E.
Acta Crystallogr. D 60:392-396(2004) · UniProtKB (1) · Mapped (2) |
| Interactions of a new alpha-aminophosphinic derivative inside the active site of TLN (thermolysin): a model for zinc-metalloendopeptidase inhibition. Selkti M., Tomas A., Gaucher J.F., Prange T., Fournie-Zaluski M.C., Chen H., Roques B.P.
Acta Crystallogr. D Biol. Crystallogr. 59:1200-1205(2003) · Mapped (1) |
| NMR structure of the HIV-1 regulatory protein VPR. Morellet N., Bouaziz S., Petitjean P., Roques B.P.
J. Mol. Biol. 327:215-227(2003) · UniProtKB (1) |
| NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol. Comparison with the Vpr N-terminal (1-51) and C-terminal (52-96) domains. Wecker K., Morellet N., Bouaziz S., Roques B.P.
Eur. J. Biochem. 269:3779-3788(2002) · UniProtKB (1) |
| Zn(2+) binding properties of single-point mutants of the C-terminal zinc finger of the HIV-1 nucleocapsid protein: evidence of a critical role of cysteine 49 in Zn(2+) dissociation. Bombarda E., Cherradi H., Morellet N., Roques B.P., Mely Y.
Biochemistry 41:4312-4320(2002) · Mapped (2) |
| Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP). Inguimbert N., Coric P., Poras H., Meudal H., Teffot F., Fournie-Zaluski M.C., Roques B.P.
J. Med. Chem. 45:1477-1486(2002) · Mapped (5) |
| Deletion of CCK2 receptor in mice results in an upregulation of the endogenous opioid system. Pommier B., Beslot F., Simon A., Pophillat M., Matsui T., Dauge V., Roques B.P., Noble F.
J. Neurosci. 22:2005-2011(2002) · Mapped (4) |
| Behavioral profile of CCK2 receptor-deficient mice. Dauge V., Sebret A., Beslot F., Matsui T., Roques B.P.
Neuropsychopharmacology 25:690-698(2001) · Mapped (4) |
| First discrete autoradiographic distribution of aminopeptidase N in various structures of rat brain and spinal cord using the selective iodinated inhibitor 125IRB 129. Noble F., Banisadr G., Jardinaud F., Popovici T., Lai-Kuen R., Chen H., Bischoff L., Parsadaniantz S.M., Fournie-Zaluski M.-C., Roques B.P.
Neuroscience 105:479-488(2001) · UniProtKB (1) |
| Mutant mice lacking the cholecystokinin2 receptor show a dopamine-dependent hyperactivity and a behavioral sensitization to morphine. Dauge V., Beslot F., Matsui T., Roques B.P.
Neurosci. Lett. 306:41-44(2001) · Mapped (4) |
| Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2. Jacotot E., Ferri K.F., El Hamel C., Brenner C., Druillennec S., Hoebeke J., Rustin P., Metivier D., Lenoir C., Geuskens M. et al.
J. Exp. Med. 193:509-519(2001) · Mapped (2) |
