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1 - 25 of 89 results for author:"Roop D.R." in Literature citations

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Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.

Huebner A.J., Dai D., Morasso M., Schmidt E.E., Schafer M., Werner S., Roop D.R.

Dev. Cell 23:1238-1246(2012) · Mapped (4)

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.

Luo Y., Dallaglio K., Chen Y., Robinson W.A., Robinson S.E., McCarter M.D., Wang J., Gonzalez R., Thompson D.C., Norris D.A. et al.

Stem Cells 30:2100-2113(2012) · Mapped (4)

Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.

Torchia E.C., Caulin C., Acin S., Terzian T., Kubick B.J., Box N.F., Roop D.R.

Oncogene 31:2680-2690(2012) · Mapped (17)

Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.

Acin S., Li Z., Mejia O., Roop D.R., El-Naggar A.K., Caulin C.

J. Pathol. 225:479-489(2011) · Mapped (24)

Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.

Terzian T., Dumble M., Arbab F., Thaller C., Donehower L.A., Lozano G., Justice M.J., Roop D.R., Box N.F.

J. Pathol. 224:540-552(2011) · Mapped (19)

Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.

Dai D., Zhu H., Wlodarczyk B., Zhang L., Li L., Li A.G., Finnell R.H., Roop D.R., Chen J.

J. Invest. Dermatol. 131:302-310(2011) · UniProtKB (1) · Mapped (57)

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.

Terzian T., Torchia E.C., Dai D., Robinson S.E., Murao K., Stiegmann R.A., Gonzalez V., Boyle G.M., Powell M.B., Pollock P.M. et al.

Pigment Cell Melanoma Res 23:781-794(2010) · Mapped (50)

Treasure or artifact: a decade of p63 research speaks for itself.

Mikkola M.L., Costanzo A., Thesleff I., Roop D.R., Koster M.I.

Cell Death Differ. 17:180-3; author reply 2010:184-6(2010) · Mapped (8)

A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.

Torchia E.C., Chen Y., Sheng H., Katayama H., Fitzpatrick J., Brinkley W.R., Caulin C., Sen S., Roop D.R.

Cancer Res. 69:7207-7215(2009) · Mapped (9)

p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.

Kim S., Choi I.F., Quante J.R., Zhang L., Roop D.R., Koster M.I.

Exp. Dermatol. 18:1016-1021(2009) · Mapped (9)

IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias.

Marinari B., Ballaro C., Koster M.I., Giustizieri M.L., Moretti F., Crosti F., Papoutsaki M., Karin M., Alema S., Chimenti S. et al.

J. Invest. Dermatol. 129:60-69(2009) · Mapped (12)

Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.

Guttormsen J., Koster M.I., Stevens J.R., Roop D.R., Williams T., Winger Q.A.

Dev. Biol. 317:187-195(2008) · Mapped (23)

Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.

Chen J., Jaeger K., Den Z., Koch P.J., Sundberg J.P., Roop D.R.

J. Invest. Dermatol. 128:270-279(2008) · UniProtKB (1) · Mapped (7)

An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.

Caulin C., Nguyen T., Lang G.A., Goepfert T.M., Brinkley B.R., Cai W.W., Lozano G., Roop D.R.

J. Clin. Invest. 117:1893-1901(2007) · Mapped (24)

Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.

Lee S., Chari N.S., Kim H.W., Wang X., Roop D.R., Cho S.H., DiGiovanni J., McDonnell T.J.

Mol. Carcinog. 46:949-957(2007) · Mapped (8)

Double-inducible gene activation system for caspase 3 and 9 in epidermis.

Shah V.R., Koster M.I., Roop D.R., Spencer D.M., Wei L., Li Q., Schwartz R.J., Chang J.

Genesis 45:194-199(2007) · Mapped (10)

p63 induces key target genes required for epidermal morphogenesis.

Koster M.I., Dai D., Marinari B., Sano Y., Costanzo A., Karin M., Roop D.R.

Proc. Natl. Acad. Sci. U.S.A. 104:3255-3260(2007) · Mapped (18)

Conflicting roles for p63 in skin development and carcinogenesis.

Koster M.I., Dai D., Roop D.R.

Cell Cycle 6:269-273(2007) · Mapped (5)

An unexpected role for keratin 10 end domains in susceptibility to skin cancer.

Chen J., Cheng X., Merched-Sauvage M., Caulin C., Roop D.R., Koch P.J.

J. Cell. Sci. 119:5067-5076(2006) · Mapped (1)

Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function.

Geng S., Mezentsev A., Kalachikov S., Raith K., Roop D.R., Panteleyev A.A.

J. Cell. Sci. 119:4901-4912(2006) · Mapped (9)

The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4.

Yu Z., Lin K.K., Bhandari A., Spencer J.A., Xu X., Wang N., Lu Z., Gill G.N., Roop D.R., Wertz P. et al.

Dev. Biol. 299:122-136(2006) · Mapped (58)

Keratin 6 is not essential for mammary gland development.

Grimm S.L., Bu W., Longley M.A., Roop D.R., Li Y., Rosen J.M.

Breast Cancer Res. 8:R29-R29(2006) · Mapped (22)

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

Keyes W.M., Vogel H., Koster M.I., Guo X., Qi Y., Petherbridge K.M., Roop D.R., Bradley A., Mills A.A.

Proc. Natl. Acad. Sci. U.S.A. 103:8435-8440(2006) · Mapped (16)

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.

Nguyen B.C., Lefort K., Mandinova A., Antonini D., Devgan V., Della Gatta G., Koster M.I., Zhang Z., Wang J., Tommasi di Vignano A. et al.

Genes Dev. 20:1028-1042(2006) · Mapped (15)

Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression.

Koster M.I., Lu S.L., White L.D., Wang X.J., Roop D.R.

Cancer Res. 66:3981-3986(2006) · Mapped (5)

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