| Suppression of the antiviral response by an influenza histone mimic. Marazzi I., Ho J.S., Kim J., Manicassamy B., Dewell S., Albrecht R.A., Seibert C.W., Schaefer U., Jeffrey K.L., Prinjha R.K. et al.
Nature 483:428-433(2012) · UniProtKB (1) |
| Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells. Hasegawa N., Sumitomo A., Fujita A., Aritome N., Mizuta S., Matsui K., Ishino R., Inoue K., Urahama N., Nose J. et al.
Mol. Cell. Biol. 32:1483-1495(2012) · Mapped (9) |
| Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. Jishage M., Malik S., Wagner U., Uberheide B., Ishihama Y., Hu X., Chait B.T., Gnatt A., Ren B., Roeder R.G.
Mol. Cell 45:51-63(2012) · Mapped (8) |
| p53 requires an intact C-terminal domain for DNA binding and transactivation. Kim H., Kim K., Choi J., Heo K., Baek H.J., Roeder R.G., An W.
J. Mol. Biol. 415:843-854(2012) · Mapped (32) |
| Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth. Jaaskelainen T., Makkonen H., Visakorpi T., Kim J., Roeder R.G., Palvimo J.J.
Mol. Cell. Endocrinol. 350:87-98(2012) · Mapped (11) |
| GlcNAcylation of histone H2B facilitates its monoubiquitination. Fujiki R., Hashiba W., Sekine H., Yokoyama A., Chikanishi T., Ito S., Imai Y., Kim J., He H.H., Igarashi K. et al.
Nature 480:557-560(2011) · UniProtKB (3) |
| Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. Biswas D., Milne T.A., Basrur V., Kim J., Elenitoba-Johnson K.S., Allis C.D., Roeder R.G.
Proc. Natl. Acad. Sci. U.S.A. 108:15751-15756(2011) · Mapped (14) |
| The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Wang L., Gural A., Sun X.J., Zhao X., Perna F., Huang G., Hatlen M.A., Vu L., Liu F., Xu H. et al.
Science 333:765-769(2011) · Mapped (11) |
| RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression. Shema E., Kim J., Roeder R.G., Oren M.
Mol. Cell 42:477-488(2011) · Mapped (6) |
| Direct interactions of OCA-B and TFII-I regulate immunoglobulin heavy-chain gene transcription by facilitating enhancer-promoter communication. Ren X., Siegel R., Kim U., Roeder R.G.
Mol. Cell 42:342-355(2011) · Mapped (12) |
| Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Jiang H., Shukla A., Wang X., Chen W.Y., Bernstein B.E., Roeder R.G.
Cell 144:513-525(2011) · UniProtKB (7) · Mapped (9) |
| The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability. Park J.H., Smith R.J., Shieh S.Y., Roeder R.G.
J. Biol. Chem. 286:10911-10917(2011) · Mapped (33) |
| Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1). Liu X., Wang D., Zhao Y., Tu B., Zheng Z., Wang L., Wang H., Gu W., Roeder R.G., Zhu W.G.
Proc. Natl. Acad. Sci. U.S.A. 108:1925-1930(2011) · UniProtKB (1) · Mapped (38) |
| The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression. Sumitomo A., Ishino R., Urahama N., Inoue K., Yonezawa K., Hasegawa N., Horie O., Matsuoka H., Kondo T., Roeder R.G. et al.
Mol. Cell. Biol. 30:4818-4827(2010) · Mapped (11) |
| A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism. Chen W., Zhang X., Birsoy K., Roeder R.G.
Proc. Natl. Acad. Sci. U.S.A. 107:10196-10201(2010) · Mapped (2) |
| Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation. Jiang P., Hu Q., Ito M., Meyer S., Waltz S., Khan S., Roeder R.G., Zhang X.
Proc. Natl. Acad. Sci. U.S.A. 107:6765-6770(2010) · Mapped (2) |
| The SANT domain of p400 ATPase represses acetyltransferase activity and coactivator function of TIP60 in basal p21 gene expression. Park J.H., Sun X.J., Roeder R.G.
Mol. Cell. Biol. 30:2750-2761(2010) · Mapped (5) |
| MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis. Grontved L., Madsen M.S., Boergesen M., Roeder R.G., Mandrup S.
Mol. Cell. Biol. 30:2155-2169(2010) · Mapped (13) |
| The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS. Kim J., Guermah M., Roeder R.G.
Cell 140:491-503(2010) · UniProtKB (6) · Mapped (4) |
| Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. Ruas J.L., Berchner-Pfannschmidt U., Malik S., Gradin K., Fandrey J., Roeder R.G., Pereira T., Poellinger L.
J. Biol. Chem. 285:2601-2609(2010) · Mapped (3) |
| Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene. Chen W., Yang Q., Roeder R.G.
Mol. Cell 35:755-768(2009) · Mapped (9) |
| Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast. Kim J., Roeder R.G.
J. Biol. Chem. 284:20582-20592(2009) · Mapped (13) |
| A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4. Lee J., Kim D.H., Lee S., Yang Q.H., Lee D.K., Lee S.K., Roeder R.G., Lee J.W.
Proc. Natl. Acad. Sci. U.S.A. 106:8513-8518(2009) · Mapped (11) |
| RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Kim J., Guermah M., McGinty R.K., Lee J.S., Tang Z., Milne T.A., Shilatifard A., Muir T.W., Roeder R.G.
Cell 137:459-471(2009) · UniProtKB (3) · Mapped (2) |
| GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Fujiki R., Chikanishi T., Hashiba W., Ito H., Takada I., Roeder R.G., Kitagawa H., Kato S.
Nature 459:455-459(2009) · UniProtKB (9) |
