| Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. Leonardi R., Frank M.W., Jackson P.D., Rock C.O., Jackowski S.
J. Biol. Chem. 284:27077-27089(2009) · Mapped (7) |
| Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases. Miller D.J., Jerga A., Rock C.O., White S.W.
Structure 16:1036-1046(2008) · UniProtKB (1) |
| Localization and regulation of mouse pantothenate kinase 2. Leonardi R., Zhang Y.M., Lykidis A., Rock C.O., Jackowski S.
FEBS Lett. 581:4639-4644(2007) · Mapped (10) |
| Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder. Hong B.S., Senisterra G., Rabeh W.M., Vedadi M., Leonardi R., Zhang Y.M., Rock C.O., Jackowski S., Park H.W.
J. Biol. Chem. 282:27984-27993(2007) · Mapped (10) |
| Coupling of fatty acid and phospholipid synthesis in Bacillus subtilis. Paoletti L., Lu Y.-J., Schujman G.E., de Mendoza D., Rock C.O.
J. Bacteriol. 189:5816-5824(2007) · UniProtKB (3) |
| Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis. Jerga A., Lu Y.-J., Schujman G.E., de Mendoza D., Rock C.O.
J. Biol. Chem. 282:21738-21745(2007) · UniProtKB (7) |
| Crystal structure and allosteric regulation of the cytoplasmic Escherichia coli L-asparaginase I. Yun M.K., Nourse A., White S.W., Rock C.O., Heath R.J.
J. Mol. Biol. 369:794-811(2007) · Mapped (1) |
| Topology and active site of PlsY: the bacterial acylphosphate:glycerol-3-phosphate acyltransferase. Lu Y.-J., Zhang F., Grimes K.D., Lee R.E., Rock C.O.
J. Biol. Chem. 282:11339-11346(2007) · UniProtKB (1) |
| Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine. Leonardi R., Rock C.O., Jackowski S., Zhang Y.M.
Proc. Natl. Acad. Sci. U.S.A. 104:1494-1499(2007) · Mapped (6) |
| Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens. Lu Y.-J., Zhang Y.-M., Grimes K.D., Qi J., Lee R.E., Rock C.O.
Mol. Cell 23:765-772(2006) · UniProtKB (5) |
| Prokaryotic type II and type III pantothenate kinases: the same monomer fold creates dimers with distinct catalytic properties. Hong B.S., Yun M.K., Zhang Y.-M., Chohnan S., Rock C.O., White S.W., Jackowski S., Park H.-W., Leonardi R.
Structure 14:1251-1261(2006) · UniProtKB (4) |
| Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. Tian Y., Jackson P., Gunter C., Wang J., Rock C.O., Jackowski S.
J. Biol. Chem. 281:28438-28449(2006) · Mapped (8) |
| Structure of RhlG, an essential beta-ketoacyl reductase in the rhamnolipid biosynthetic pathway of Pseudomonas aeruginosa. Miller D.J., Zhang Y.M., Rock C.O., White S.W.
J. Biol. Chem. 281:18025-18032(2006) · Mapped (1) |
| Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae. Zhang Y.M., Hurlbert J., White S.W., Rock C.O.
J. Biol. Chem. 281:17390-17399(2006) · Mapped (2) |
| Serum opacity factor, a streptococcal virulence factor that binds to apolipoproteins A-I and A-II and disrupts high density lipoprotein structure. Courtney H.S., Zhang Y.M., Frank M.W., Rock C.O.
J. Biol. Chem. 281:5515-5521(2006) · Mapped (2) |
| Biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration. Zhang Y.M., Rock C.O., Jackowski S.
J. Biol. Chem. 281:107-114(2006) · Mapped (6) |
| Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters. Zhang Y.M., Rock C.O., Jackowski S.
J. Biol. Chem. 280:32594-32601(2005) · Mapped (8) |
| Lysophospholipid flipping across the Escherichia coli inner membrane catalyzed by a transporter (LplT) belonging to the major facilitator superfamily. Harvat E.M., Zhang Y.-M., Tran C.V., Zhang Z., Frank M.W., Rock C.O., Saier M.H. Jr.
J. Biol. Chem. 280:12028-12034(2005) · UniProtKB (1) |
| A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A. Leonardi R., Chohnan S., Zhang Y.-M., Virga K.G., Lee R.E., Rock C.O., Jackowski S.
J. Biol. Chem. 280:3314-3322(2005) · UniProtKB (1) |
| The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa. Kimber M.S., Martin F., Lu Y., Houston S., Vedadi M., Dharamsi A., Fiebig K.M., Schmid M., Rock C.O.
J. Biol. Chem. 279:52593-52602(2004) · Mapped (1) |
| The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites. Ivey R.A., Zhang Y.M., Virga K.G., Hevener K., Lee R.E., Rock C.O., Jackowski S., Park H.W.
J. Biol. Chem. 279:35622-35629(2004) · Mapped (1) |
| Cofactor-induced conformational rearrangements establish a catalytically competent active site and a proton relay conduit in FabG. Price A.C., Zhang Y.M., Rock C.O., White S.W.
Structure 12:417-428(2004) · Mapped (1) |
| Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor. Sampaio M.-M., Chevance F., Dippel R., Eppler T., Schlegel A., Boos W., Lu Y.-J., Rock C.O.
J. Biol. Chem. 279:5537-5548(2004) · UniProtKB (2) |
| The 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniae. Price A.C., Rock C.O., White S.W.
J. Bacteriol. 185:4136-4143(2003) · Mapped (1) |
| Crystal structures of the Dab homology domains of mouse disabled 1 and 2. Yun M., Keshvara L., Park C.G., Zhang Y.M., Dickerson J.B., Zheng J., Rock C.O., Curran T., Park H.W.
J. Biol. Chem. 278:36572-36581(2003) · UniProtKB (1) · Mapped (10) |