| Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology. Lawlor K.T., O'Keefe L.V., Samaraweera S.E., van Eyk C.L., Richards R.I.
PLoS ONE 7:e38516-e38516(2012) · Mapped (24) |
| Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases. Lawlor K.T., O'Keefe L.V., Samaraweera S.E., van Eyk C.L., McLeod C.J., Maloney C.A., Dang T.H., Suter C.M., Richards R.I.
Hum. Mol. Genet. 20:3757-3768(2011) · Mapped (61) |
| Perturbation of the Akt/Gsk3-beta signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs. van Eyk C.L., O'Keefe L.V., Lawlor K.T., Samaraweera S.E., McLeod C.J., Price G.R., Venter D.J., Richards R.I.
Hum. Mol. Genet. 20:2783-2794(2011) · Mapped (51) |
| Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. O'Keefe L.V., Colella A., Dayan S., Chen Q., Choo A., Jacob R., Price G., Venter D., Richards R.I.
Hum. Mol. Genet. 20:497-509(2011) · Mapped (54) |
| Selective neuronal requirement for huntingtin in the developing zebrafish. Henshall T.L., Tucker B., Lumsden A.L., Nornes S., Lardelli M.T., Richards R.I.
Hum. Mol. Genet. 18:4830-4842(2009) · Mapped (6) |
| Huntingtin-deficient zebrafish exhibit defects in iron utilization and development. Lumsden A.L., Henshall T.L., Dayan S., Lardelli M.T., Richards R.I.
Hum. Mol. Genet. 16:1905-1920(2007) · Mapped (11) |
| Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome. Tucker B., Richards R.I., Lardelli M.
Hum. Mol. Genet. 15:3446-3458(2006) · Mapped (5) |
| Molecular genetics of pseudoxanthoma elasticum: type and frequency of mutations in ABCC6. Miksch S., Lumsden A., Guenther U.P., Foernzler D., Christen-Zach S., Daugherty C., Ramesar R.K., Lebwohl M., Hohl D., Neldner K.H. et al.
Hum. Mutat. 26:235-248(2005) · UniProtKB (1) · Mapped (5) |
| FRA16D common chromosomal fragile site oxido-reductase (FOR/WWOX) protects against the effects of ionizing radiation in Drosophila. O'Keefe L.V., Liu Y., Perkins A., Dayan S., Saint R., Richards R.I.
Oncogene 24:6590-6596(2005) · UniProtKB (1) · Mapped (3) |
| The pathogenic agent in Drosophila models of 'polyglutamine' diseases. McLeod C.J., O'Keefe L.V., Richards R.I.
Hum. Mol. Genet. 14:1041-1048(2005) · Mapped (1) |
| Detection of a novel missense mutation and second recurrent mutation in the CACNA1A gene in individuals with EA-2 and FHM. Friend K.L., Crimmins D., Phan T.G., Sue C.M., Colley A., Fung V.S., Morris J.G., Sutherland G.R., Richards R.I.
Hum. Genet. 105:261-265(1999) · UniProtKB (1) |
| Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells. Ried K., Finnis M., Hobson L., Mangelsdorf M., Dayan S., Nancarrow J.K., Woollatt E., Kremmidiotis G., Gardner A., Venter D. et al.
Hum. Mol. Genet. 9:1651-1663(2000) · UniProtKB (1) |
| Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3. Centola M., Chen X., Sood R., Deng Z., Aksentijevich I., Blake T., Ricke D.O., Chen X., Wood G., Zaks N. et al.
Genome Res. 8:1172-1191(1998) · UniProtKB (2) |
| Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Aksentijevich I., Centola M., Deng Z., Sood R., Balow J.E. Jr., Wood G., Zaks N., Mansfield E., Chen X., Eisenberg S. et al.
Cell 90:797-807(1997) · UniProtKB (1) |
| Chromosomal localization of the human P2y6 purinoceptor gene and phylogenetic analysis of the P2y purinoceptor family. Somers G.R., Hammet F., Woollatt E., Richards R.I., Southey M.C., Venter D.J.
Genomics 44:127-130(1997) · UniProtKB (1) |
| Marfan Database (second edition): software and database for the analysis of mutations in the human FBN1 gene. Collod-Beroud G., Beroud C., Ades L., Black C., Boxer M., Brock D.J., Godfrey M., Hayward C., Karttunen L., Milewicz D. et al.
Nucleic Acids Res. 25:147-150(1997) · UniProtKB (1) |
| Characterisation of four novel fibrillin-1 (FBN1) mutations in Marfan syndrome. Ades L.C., Haan E.A., Colley A.F., Richards R.I.
J. Med. Genet. 33:665-671(1996) · UniProtKB (1) |
| Isolation and characterization of transcribed sequences from a chromosome 16 hn-cDNA library and the physical mapping of genes and transcribed sequences using a high-resolution somatic cell panel of human chromosome 16. Whitmore S.A., Apostolou S., Lane S., Nancarrow J.K., Phillips H.A., Richards R.I., Sutherland G.R., Callen D.F.
Genomics 20:169-175(1994) · UniProtKB (1) · Mapped (1) |
| Human metallothionein genes -- primary structure of the metallothionein-II gene and a related processed gene. Karin M., Richards R.I.
Nature 299:797-802(1982) · UniProtKB (1) |
| Primary structure and evolution of rat growth hormone gene. Barta A., Richards R.I., Baxter J.D., Shine J.
Proc. Natl. Acad. Sci. U.S.A. 78:4867-4871(1981) · UniProtKB (1) |
| Mouse kallikrein arginyl-esteropeptidase genes: analysis of cloned cDNAs suggests rapid functional divergence from a common ancestral sequence. Nordeen S.K., Mason A.J., Richards R.I., Baxter J.D., Shine J.
DNA 1:309-311(1982) · UniProtKB (1) |
| Human metallothionein genes: molecular cloning and sequence analysis of the mRNA. Karin M., Richards R.I.
Nucleic Acids Res. 10:3165-3173(1982) · UniProtKB (1) |
| Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Mason A.J., Evans B.A., Cox D.R., Shine J., Richards R.I.
Nature 303:300-307(1983) · UniProtKB (1) · Mapped (7) |
| Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. Richards R.I., Heguy A., Karin M.
Cell 37:263-272(1984) · UniProtKB (1) |
| Chicken globin genes. Nucleotide sequence of cDNA clones coding for the alpha-globin expressed during hemolytic anemia. Richards R.I., Wells J.R.E.
J. Biol. Chem. 255:9306-9311(1980) · UniProtKB (1) |
