| The reaction mechanism of allene oxide synthase: Interplay of theoretical QM/MM calculations and experimental investigations. Cho K.B., Lai W., Hamberg M., Raman C.S., Shaik S.
Arch. Biochem. Biophys. 507:14-25(2011) · Mapped (1) |
| Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Guo D.-C., Papke C.L., Tran-Fadulu V., Regalado E.S., Avidan N., Johnson R.J., Kim D.H., Pannu H., Willing M.C., Sparks E. et al.
Am. J. Hum. Genet. 84:617-627(2009) · UniProtKB (1) · Mapped (3) |
| Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes. Lee D.-S., Nioche P., Hamberg M., Raman C.S.
Nature 455:363-368(2008) · UniProtKB (4) |
| A new mutation within the porphobilinogen deaminase gene leading to a truncated protein as a cause of acute intermittent porphyria in an extended Indian family. Flachsova E., Verma I.C., Ulbrichova D., Saxena R., Zeman J., Saudek V., Raman C.S., Martasek P.
Folia Biol. (Praha) 53:194-201(2007) · Mapped (6) |
| Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections. Guo D.-C., Pannu H., Tran-Fadulu V., Papke C.L., Yu R.K., Avidan N., Bourgeois S., Estrera A.L., Safi H.J., Sparks E. et al.
Nat. Genet. 39:1488-1493(2007) · UniProtKB (1) · Mapped (3) |
| MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II. Pannu H., Tran-Fadulu V., Papke C.L., Scherer S., Liu Y., Presley C., Guo D., Estrera A.L., Safi H.J., Brasier A.R. et al.
Hum. Mol. Genet. 16:2453-2462(2007) · Mapped (27) |
| Structural basis of hereditary coproporphyria. Lee D.-S., Flachsova E., Bodnarova M., Demeler B., Martasek P., Raman C.S.
Proc. Natl. Acad. Sci. U.S.A. 102:14232-14237(2005) · UniProtKB (1) · Mapped (1) |
| Mutations in transforming growth factor-beta receptor type II cause familial thoracic aortic aneurysms and dissections. Pannu H., Fadulu V.T., Chang J., Lafont A., Hasham S.N., Sparks E., Giampietro P.F., Zaleski C., Estrera A.L., Safi H.J. et al.
Circulation 112:513-520(2005) · UniProtKB (1) · Mapped (3) |
| Femtomolar sensitivity of a NO sensor from Clostridium botulinum. Nioche P., Berka V., Vipond J., Minton N., Tsai A.L., Raman C.S.
Science 306:1550-1553(2004) · UniProtKB (2) |
| A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor. Kurokawa H., Lee D.-S., Watanabe M., Sagami I., Mikami B., Raman C.S., Shimizu T.
J. Biol. Chem. 279:20186-20193(2004) · UniProtKB (1) |
| Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. Raman C.S., Li H., Martasek P., Southan G., Masters B.S.S., Poulos T.L.
Biochemistry 40:13448-13455(2001) · UniProtKB (1) |
| Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin. Kotsonis P., Frohlich L.G., Raman C.S., Li H., Berg M., Gerwig R., Groehn V., Kang Y., Al-Masoudi N., Taghavi-Moghadam S. et al.
J. Biol. Chem. 276:49133-49141(2001) · UniProtKB (1) |
| Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. Raman C.S., Li H., Martasek P., Babu B.R., Griffith O.W., Southan G., Masters B.S.S., Poulos T.L.
J. Biol. Chem. 276:26486-26491(2001) · UniProtKB (1) |
| Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors. Li H., Raman C.S., Martasek P., Masters B.S.S., Poulos T.L.
Biochemistry 40:5399-5406(2001) · UniProtKB (1) · Mapped (1) |
| Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas. Li H., Raman C.S., Martasek P., Kral V., Masters B.S.S., Poulos T.L.
J. Inorg. Biochem. 81:133-139(2000) · UniProtKB (1) |
| Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase. Li H., Raman C.S., Glaser C.B., Blasko E., Young T.A., Parkinson J.F., Whitlow M., Poulos T.L.
J. Biol. Chem. 274:21276-21284(1999) · UniProtKB (1) |
| Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Raman C.S., Li H., Martasek P., Kral V., Masters B.S.S., Poulos T.L.
Cell 95:939-950(1998) · UniProtKB (1) |
