| Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells. Crotzer V.L., Matute J.D., Arias A.A., Zhao H., Quilliam L.A., Dinauer M.C., Blum J.S.
J. Immunol. 189:3800-3804(2012) · Mapped (5) |
| PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. Bai Y., Luo Y., Liu S., Zhang L., Shen K., Dong Y., Walls C.D., Quilliam L.A., Wells C.D., Cao Y. et al.
J. Biol. Chem. 286:42316-42324(2011) · Mapped (41) |
| Cool-1/betaPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion. Kepner E.M., Yoder S.M., Oh E., Kalwat M.A., Wang Z., Quilliam L.A., Thurmond D.C.
Am. J. Physiol. Endocrinol. Metab. 301:E1072-80(2011) · Mapped (5) |
| Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. Awasthi A., Samarakoon A., Chu H., Kamalakannan R., Quilliam L.A., Chrzanowska-Wodnicka M., White G.C., Malarkannan S.
J. Exp. Med. 207:1923-1938(2010) · Mapped (18) |
| Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. Panchatcharam M., Miriyala S., Yang F., Leitges M., Chrzanowska-Wodnicka M., Quilliam L.A., Anaya P., Morris A.J., Smyth S.S.
Int. J. Biochem. Cell Biol. 42:965-974(2010) · Mapped (4) |
| Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines. Woolfrey K.M., Srivastava D.P., Photowala H., Yamashita M., Barbolina M.V., Cahill M.E., Xie Z., Jones K.A., Quilliam L.A., Prakriya M. et al.
Nat. Neurosci. 12:1275-1284(2009) · Mapped (3) |
| Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions. Yan J., Li F., Ingram D.A., Quilliam L.A.
Mol. Cell. Biol. 28:5803-5810(2008) · Mapped (10) |
| Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. Li Y., Yan J., De P., Chang H.C., Yamauchi A., Christopherson K.W., Paranavitana N.C., Peng X., Kim C., Munugalavadla V. et al.
J. Immunol. 179:8322-8331(2007) · Mapped (5) |
| The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. Ming W., Li S., Billadeau D.D., Quilliam L.A., Dinauer M.C.
Mol. Cell. Biol. 27:312-323(2007) · Mapped (28) |
| The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane. Li Y., Asuri S., Rebhun J.F., Castro A.F., Paranavitana N.C., Quilliam L.A.
J. Biol. Chem. 281:2506-2514(2006) · Mapped (5) |
| AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner. Felekkis K.N., Narsimhan R.P., Near R., Castro A.F., Zheng Y., Quilliam L.A., Lerner A.
Mol. Cancer Res. 3:32-41(2005) · Mapped (5) |
| Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. Wittchen E.S., Worthylake R.A., Kelly P., Casey P.J., Quilliam L.A., Burridge K.
J. Biol. Chem. 280:11675-11682(2005) · Mapped (3) |
| Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. Arthur W.T., Quilliam L.A., Cooper J.A.
J. Cell Biol. 167:111-122(2004) · Mapped (7) |
| Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner. Castro A.F., Rebhun J.F., Clark G.J., Quilliam L.A.
J. Biol. Chem. 278:32493-32496(2003) · Mapped (3) |
| Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions. Li S., Yamauchi A., Marchal C.C., Molitoris J.K., Quilliam L.A., Dinauer M.C.
J. Immunol. 169:5043-5051(2002) · Mapped (8) |
| Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells. Gu Y., Byrne M.C., Paranavitana N.C., Aronow B., Siefring J.E., D'Souza M., Horton H.F., Quilliam L.A., Williams D.A.
Mol. Cell. Biol. 22:7645-7657(2002) · Mapped (2) |
| RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. Reuther G.W., Lambert Q.T., Rebhun J.F., Caligiuri M.A., Quilliam L.A., Der C.J.
J. Biol. Chem. 277:30508-30514(2002) · UniProtKB (1) |
| Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation. Mei F.C., Qiao J., Tsygankova O.M., Meinkoth J.L., Quilliam L.A., Cheng X.
J. Biol. Chem. 277:11497-11504(2002) · Mapped (8) |
| Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction. Rebhun J.F., Castro A.F., Quilliam L.A.
J. Biol. Chem. 275:34901-34908(2000) · UniProtKB (3) |
| Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral. Rebhun J.F., Chen H., Quilliam L.A.
J. Biol. Chem. 275:13406-13410(2000) · UniProtKB (7) |
| Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress. Sood R., Porter A.C., Ma K., Quilliam L.A., Wek R.C.
Biochem. J. 346:281-293(2000) · UniProtKB (3) |
| M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6. Quilliam L.A., Castro A.F., Rogers-Graham K.S., Martin C.B., Der C.J., Bi C.
J. Biol. Chem. 274:23850-23857(1999) · Mapped (14) |
| Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck. Braverman L.E., Quilliam L.A.
J. Biol. Chem. 274:5542-5549(1999) · UniProtKB (7) · Mapped (3) |
| A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. Lander H.M., Hajjar D.P., Hempstead B.L., Mirza U.A., Chait B.T., Campbell S., Quilliam L.A.
J. Biol. Chem. 272:4323-4326(1997) · UniProtKB (1) |
| Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling. Quilliam L.A., Lambert Q.T., Mickelson-Young L.A., Westwick J.K., Sparks A.B., Kay B.K., Jenkins N.A., Gilbert D.J., Copeland N.G., Der C.J.
J. Biol. Chem. 271:28772-28776(1996) · UniProtKB (3) · Mapped (17) |
