1 - 25 of 28 results for author:"Polakiewicz R.D." in Literature citations
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| Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14. Zhang P., Guo A., Possemato A., Wang C., Beard L., Carlin C., Markowitz S.D., Polakiewicz R.D., Wang Z. Oncogene 0:0-0(2012) · UniProtKB (2) |
| Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Hitosugi T., Fan J., Chung T.W., Lythgoe K., Wang X., Xie J., Ge Q., Gu T.L., Polakiewicz R.D., Roesel J.L. et al. |
| Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells. Fan J., Hitosugi T., Chung T.W., Xie J., Ge Q., Gu T.L., Polakiewicz R.D., Chen G.Z., Boggon T.J., Lonial S. et al. Mol. Cell. Biol. 31:4938-4950(2011) · Mapped (2) |
| Survey of activated FLT3 signaling in leukemia. Gu T.L., Nardone J., Wang Y., Loriaux M., Villen J., Beausoleil S., Tucker M., Kornhauser J., Ren J., MacNeill J. et al. PLoS ONE 6:e19169-e19169(2011) · Mapped (2) |
| p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells. Kang S., Elf S., Lythgoe K., Hitosugi T., Taunton J., Zhou W., Xiong L., Wang D., Muller S., Fan S. et al. J. Clin. Invest. 120:1165-1177(2010) · Mapped (6) |
| Identification of activated Tnk1 kinase in Hodgkin's lymphoma. Gu T.L., Cherry J., Tucker M., Wu J., Reeves C., Polakiewicz R.D. Leukemia 24:861-865(2010) · Mapped (1) |
| Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor. Pecquet C., Staerk J., Chaligne R., Goss V., Lee K.A., Zhang X., Rush J., Van Hees J., Poirel H.A., Scheiff J.M. et al. Blood 115:1037-1048(2010) · Mapped (3) |
| Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth. Hitosugi T., Kang S., Vander Heiden M.G., Chung T.W., Elf S., Lythgoe K., Dong S., Lonial S., Wang X., Chen G.Z. et al. Sci Signal 2:ra73-ra73(2009) · Mapped (9) |
| Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer. Yu J., Kane S., Wu J., Benedettini E., Li D., Reeves C., Innocenti G., Wetzel R., Crosby K., Becker A. et al. Clin. Cancer Res. 15:3023-3028(2009) · Mapped (19) |
| The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL. Boccalatte F.E., Voena C., Riganti C., Bosia A., D'Amico L., Riera L., Cheng M., Ruggeri B., Jensen O.N., Goss V.L. et al. Blood 113:2776-2790(2009) · Mapped (26) |
| Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. Rong L., Livingstone M., Sukarieh R., Petroulakis E., Gingras A.C., Crosby K., Smith B., Polakiewicz R.D., Pelletier J., Ferraiuolo M.A. et al. RNA 14:1318-1327(2008) · Mapped (6) |
| HDAC6 is required for epidermal growth factor-induced beta-catenin nuclear localization. Li Y., Zhang X., Polakiewicz R.D., Yao T.P., Comb M.J. J. Biol. Chem. 283:12686-12690(2008) · Mapped (12) |
| Signaling networks assembled by oncogenic EGFR and c-Met. Guo A., Villen J., Kornhauser J., Lee K.A., Stokes M.P., Rikova K., Possemato A., Nardone J., Innocenti G., Wetzel R. et al. Proc. Natl. Acad. Sci. U.S.A. 105:692-697(2008) · Mapped (41) |
| Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J., Lee K., Reeves C., Li Y. et al. Cell 131:1190-1203(2007) · UniProtKB (6) |
| FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Kang S., Dong S., Gu T.L., Guo A., Cohen M.S., Lonial S., Khoury H.J., Fabbro D., Gilliland D.G., Bergsagel P.L. et al. |
| A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia. Gu T.L., Mercher T., Tyner J.W., Goss V.L., Walters D.K., Cornejo M.G., Reeves C., Popova L., Lee K., Heinrich M.C. et al. Blood 110:323-333(2007) · Mapped (14) |
| Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. Zhang X., Guo A., Yu J., Possemato A., Chen Y., Zheng W., Polakiewicz R.D., Kinzler K.W., Vogelstein B., Velculescu V.E. et al. Proc. Natl. Acad. Sci. U.S.A. 104:4060-4064(2007) · Mapped (13) |
| Dephosphorylation by default, a potential mechanism for regulation of insulin receptor substrate-1/2, Akt, and ERK1/2. Zhande R., Zhang W., Zheng Y., Pendleton E., Li Y., Polakiewicz R.D., Sun X.J. J. Biol. Chem. 281:39071-39080(2006) · Mapped (27) |
| Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia. Gu T.-L., Goss V.L., Reeves C., Popova L., Nardone J., Macneill J., Walters D.K., Wang Y., Rush J., Comb M.J. et al. Blood 108:4202-4204(2006) · UniProtKB (2) |
| Activating alleles of JAK3 in acute megakaryoblastic leukemia. Walters D.K., Mercher T., Gu T.L., O'Hare T., Tyner J.W., Loriaux M., Goss V.L., Lee K.A., Eide C.A., Wong M.J. et al. Cancer Cell 10:65-75(2006) · Mapped (6) |
| Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2. Dorsch M., Wang A., Cheng H., Lu C., Bielecki A., Charron K., Clauser K., Ren H., Polakiewicz R.D., Parsons T. et al. Cell. Signal. 18:2223-2229(2006) · UniProtKB (1) · Mapped (4) |
| JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model. Mercher T., Wernig G., Moore S.A., Levine R.L., Gu T.L., Frohling S., Cullen D., Polakiewicz R.D., Bernard O.A., Boggon T.J. et al. Blood 108:2770-2779(2006) · Mapped (9) |
| Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.-M., Polakiewicz R.D., Comb M.J. Nat. Biotechnol. 23:94-101(2005) · UniProtKB (224) |
| Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). Li Y., Soos T.J., Li X., Wu J., Degennaro M., Sun X., Littman D.R., Birnbaum M.J., Polakiewicz R.D. J. Biol. Chem. 279:45304-45307(2004) · UniProtKB (2) · Mapped (3) |
| Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice. Cheung W.C., Kim J.S., Linden M., Peng L., Van Ness B., Polakiewicz R.D., Janz S. J. Clin. Invest. 113:1763-1773(2004) · Mapped (6) |