| Neutralizing IL-6 reduces human arterial allograft rejection by allowing emergence of CD161+ CD4+ regulatory T cells. Fogal B., Yi T., Wang C., Rao D.A., Lebastchi A., Kulkarni S., Tellides G., Pober J.S.
J. Immunol. 187:6268-6280(2011) · Mapped (5) |
| An artificial antigen-presenting cell with paracrine delivery of IL-2 impacts the magnitude and direction of the T cell response. Steenblock E.R., Fadel T., Labowsky M., Pober J.S., Fahmy T.M.
J. Biol. Chem. 286:34883-34892(2011) · Mapped (12) |
| AIP1 prevents graft arteriosclerosis by inhibiting interferon-gamma-dependent smooth muscle cell proliferation and intimal expansion. Yu L., Qin L., Zhang H., He Y., Chen H., Pober J.S., Tellides G., Min W.
Circ. Res. 109:418-427(2011) · Mapped (13) |
| MEK5 is activated by shear stress, activates ERK5 and induces KLF4 to modulate TNF responses in human dermal microvascular endothelial cells. Clark P.R., Jensen T.J., Kluger M.S., Morelock M., Hanidu A., Qi Z., Tatake R.J., Pober J.S.
Microcirculation 18:102-117(2011) · Mapped (4) |
| CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. Zhou J., Tang P.C., Qin L., Gayed P.M., Li W., Skokos E.A., Kyriakides T.R., Pober J.S., Tellides G.
J. Exp. Med. 207:1951-1966(2010) · Mapped (8) |
| Tumor necrosis factor receptor expression and signaling in renal cell carcinoma. Al-Lamki R.S., Sadler T.J., Wang J., Reid M.J., Warren A.Y., Movassagh M., Lu W., Mills I.G., Neal D.E., Burge J. et al.
Am. J. Pathol. 177:943-954(2010) · Mapped (4) |
| Targeting of tumor necrosis factor receptor 1 to low density plasma membrane domains in human endothelial cells. D'Alessio A., Kluger M.S., Li J.H., Al-Lamki R., Bradley J.R., Pober J.S.
J. Biol. Chem. 285:23868-23879(2010) · Mapped (15) |
| Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. Suarez Y., Wang C., Manes T.D., Pober J.S.
J. Immunol. 184:21-25(2010) · Mapped (22) |
| TNF receptors differentially signal and are differentially expressed and regulated in the human heart. Al-Lamki R.S., Brookes A.P., Wang J., Reid M.J., Parameshwar J., Goddard M.J., Tellides G., Wan T., Min W., Pober J.S. et al.
Am. J. Transplant. 9:2679-2696(2009) · Mapped (17) |
| Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells. Li J.H., D'Alessio A., Pober J.S.
Am. J. Pathol. 175:1124-1135(2009) · Mapped (8) |
| Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cells. Gerber S.A., Yatsula B., Maier C.L., Sadler T.J., Whittaker L.W., Pober J.S.
Arterioscler. Thromb. Vasc. Biol. 29:1363-1369(2009) · Mapped (8) |
| FOXO3a regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells. Ding B., Kirkiles-Smith N.C., Pober J.S.
J. Biol. Chem. 284:19331-19339(2009) · Mapped (11) |
| Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Eid R.E., Rao D.A., Zhou J., Lo S.F., Ranjbaran H., Gallo A., Sokol S.I., Pfau S., Pober J.S., Tellides G.
Circulation 119:1424-1432(2009) · Mapped (15) |
| Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection. Rao D.A., Eid R.E., Qin L., Yi T., Kirkiles-Smith N.C., Tellides G., Pober J.S.
J. Exp. Med. 205:3145-3158(2008) · Mapped (6) |
| Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Suarez Y., Fernandez-Hernando C., Yu J., Gerber S.A., Harrison K.D., Pober J.S., Iruela-Arispe M.L., Merkenschlager M., Sessa W.C.
Proc. Natl. Acad. Sci. U.S.A. 105:14082-14087(2008) · Mapped (7) |
| IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells. Gerber S.A., Pober J.S.
J. Immunol. 181:1052-1062(2008) · Mapped (10) |
| Antiapoptotic activities of bcl-2 correlate with vascular maturation and transcriptional modulation of human endothelial cells. Enis D.R., Dunmore B., Johnson N., Pober J.S., Print C.G.
Endothelium 15:59-71(2008) · Mapped (4) |
| Antigen presentation by human microvascular endothelial cells triggers ICAM-1-dependent transendothelial protrusion by, and fractalkine-dependent transendothelial migration of, effector memory CD4+ T cells. Manes T.D., Pober J.S.
J. Immunol. 180:8386-8392(2008) · Mapped (9) |
| Regulation of arterial-venous differences in tumor necrosis factor responsiveness of endothelial cells by anatomic context. Liu M., Kluger M.S., D'Alessio A., Garcia-Cardena G., Pober J.S.
Am. J. Pathol. 172:1088-1099(2008) · Mapped (6) |
| TL1A both promotes and protects from renal inflammation and injury. Al-Lamki R.S., Wang J., Tolkovsky A.M., Bradley J.A., Griffin J.L., Thiru S., Wang E.C., Bolton E., Min W., Moore P. et al.
J. Am. Soc. Nephrol. 19:953-960(2008) · Mapped (4) |
| Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation. Bai Y., Ahmad U., Wang Y., Li J.H., Choy J.C., Kim R.W., Kirkiles-Smith N., Maher S.E., Karras J.G., Bennett C.F. et al.
J. Biol. Chem. 283:6832-6842(2008) · Mapped (31) |
| Induction of indoleamine 2,3-dioxygenase in vascular smooth muscle cells by interferon-gamma contributes to medial immunoprivilege. Cuffy M.C., Silverio A.M., Qin L., Wang Y., Eid R., Brandacher G., Lakkis F.G., Fuchs D., Pober J.S., Tellides G.
J. Immunol. 179:5246-5254(2007) · Mapped (2) |
| Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation. Wang Y., Bai Y., Qin L., Zhang P., Yi T., Teesdale S.A., Zhao L., Pober J.S., Tellides G.
Circ. Res. 101:560-569(2007) · Mapped (23) |
| RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. Zhang H., Zhang R., Zhang H., Lin Y., Li J., Pober J.S., Min W.
J. Biol. Chem. 282:14788-14796(2007) · Mapped (19) |
| Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Suarez Y., Fernandez-Hernando C., Pober J.S., Sessa W.C.
Circ. Res. 100:1164-1173(2007) · Mapped (6) |