| Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families. Velho G., Blanche H., Vaxillaire M., Bellanne-Chantelot C., Pardini V.C., Timsit J., Passa P., Deschamps I., Robert J.-J., Weber I.T. et al.
Diabetologia 40:217-224(1997) · UniProtKB (1) |
| Regulation of rat liver glucose-6-phosphatase gene expression in different nutritional and hormonal states: gene structure and 5'-flanking sequence. Argaud D., Zhang Q., Pan W., Maitra S., Pilkis S.J., Lange A.J.
Diabetes 45:1563-1571(1996) · UniProtKB (1) |
| Crystal structure of the rat liver fructose-2,6-bisphosphatase based on selenomethionine multiwavelength anomalous dispersion phases. Lee Y.-H., Ogata C., Pflugrath J.W., Levitt D.G., Sarma R., Banaszak L.J., Pilkis S.J.
Biochemistry 35:6010-6019(1996) · UniProtKB (1) |
| Identification of glucokinase mutations in subjects with gestational diabetes mellitus. Stoffel M., Bell K.L., Blackburn C.L., Powell K.L., Seo T.S., Takeda J., Vionnet N., Xiang K.-S., Gidh-Jain M., Pilkis S.J. et al.
Diabetes 42:937-940(1993) · UniProtKB (1) · Mapped (3) |
| Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships. Gidh-Jain M., Takeda J., Xu L.Z., Lange A.J., Vionnet N., Stoffel M., Froguel P., Velho G., Sun D., Cohen D. et al.
Proc. Natl. Acad. Sci. U.S.A. 90:1932-1936(1993) · UniProtKB (1) |
| Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of Asp-118 and Asp-121 in catalysis. El-Maghrabi M.R., Gidh-Jain M., Austin L.R., Pilkis S.J.
J. Biol. Chem. 268:9466-9472(1993) · UniProtKB (1) |
| Structure/function studies of human beta-cell glucokinase. Enzymatic properties of a sequence polymorphism, mutations associated with diabetes, and other site-directed mutants. Takeda J., Gidh-Jain M., Xu L.Z., Froguel P., Velho G., Vaxillaire M., Cohen D., Shimada F., Makino H., Nishi S. et al.
J. Biol. Chem. 268:15200-15204(1993) · UniProtKB (1) |
| Isolation of a cDNA for the catalytic subunit of rat liver glucose-6-phosphatase: regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP. Lange A.J., Argaud D.M., El-Maghrabi M.R., Pan W., Subir M., Pilkis S.J.
Biochem. Biophys. Res. Commun. 201:302-309(1994) · UniProtKB (1) · Mapped (3) |
| Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B. St Charles R., Harrison R.W., Bell G.I., Pilkis S.J., Weber I.T.
Diabetes 43:784-791(1994) · UniProtKB (1) |
| Glucokinase: structural analysis of a protein involved in susceptibility to diabetes. Pilkis S.J., Weber I.T., Harrison R.W., Bell G.I.
J. Biol. Chem. 269:21925-21928(1994) · Mapped (13) |
| The allosteric site of human liver fructose-1,6-bisphosphatase. Analysis of six AMP site mutants based on the crystal structure. Gidh-Jain M., Zhang Y., van Poelje P.D., Liang J.Y., Huang S., Kim J., Elliott J.T., Erion M.D., Pilkis S.J., Raafat el-Maghrabi M.
J. Biol. Chem. 269:27732-27738(1994) · Mapped (1) |
| Isolation of a cDNA for chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Li L., Lange A.J., Pilkis S.J.
Biochem. Biophys. Res. Commun. 190:397-405(1993) · UniProtKB (1) |
| Cloning and expression of a catalytic core bovine brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Ventura F., Ambrosio S., Bartrons R., El-Maghrabi M.R., Lange A.J., Pilkis S.J.
Biochem. Biophys. Res. Commun. 209:1140-1148(1995) · UniProtKB (1) |
| Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency. El-Maghrabi M.R., Lang A.J., Jiang W., Yamagata K., Stoffel M., Takeda J., Fernald A.A., le Beau M.M., Bell G.I., Baker L. et al.
Genomics 27:520-525(1995) · UniProtKB (1) |
| Active site sequence of hepatic fructose-2,6-bisphosphatase. Homology in primary structure with phosphoglycerate mutase. Pilkis S.J., Lively M.O., El-Maghrabi M.R.
J. Biol. Chem. 262:12672-12675(1987) · UniProtKB (1) |
| Isolation of a cDNA clone for rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase. Colosa A.D., Lively M.O., El-Maghrabi M.R., Pilkis S.J.
Biochem. Biophys. Res. Commun. 143:1092-1098(1987) · UniProtKB (2) |
| The amino acid sequence of rat liver glucokinase deduced from cloned cDNA. Andreone T.L., Printz R.L., Pilkis S.J., Magnuson M.A., Granner D.K.
J. Biol. Chem. 264:363-369(1989) · UniProtKB (1) · Mapped (2) |
| Induction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA by refeeding and insulin. Colosia A.D., Marker A.J., Lange A.J., El-Maghrabi M.R., Granner D.K., Tauler A., Pilkis J., Pilkis S.J.
J. Biol. Chem. 263:18669-18677(1988) · UniProtKB (1) |
| cDNA sequence of rat liver fructose-1,6-bisphosphatase and evidence for down-regulation of its mRNA by insulin. El-Maghrabi M.R., Pilkis J., Marker A.J., Colosia A.D., D'Angelo G., Fraser B.A., Pilkis S.J.
Proc. Natl. Acad. Sci. U.S.A. 85:8430-8434(1988) · UniProtKB (1) · Mapped (1) |
| Complete amino acid sequence of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Lively M.O., El-Maghrabi M.R., Pilkis J., D'Angelo G., Colosia A.D., Ciavola J.A., Fraser B.A., Pilkis S.J.
J. Biol. Chem. 263:839-849(1988) · UniProtKB (1) |
| Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Bazan J.F., Fletterick R.J., Pilkis S.J.
Proc. Natl. Acad. Sci. U.S.A. 86:9642-9646(1989) · UniProtKB (1) |
| Sequence of human liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Lange A.J., Pilkis S.J.
Nucleic Acids Res. 18:3652-3652(1990) · UniProtKB (1) |
| The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression. El-Maghrabi M.R., Lange A.J., Kummel L., Pilkis S.J.
J. Biol. Chem. 266:2115-2120(1991) · UniProtKB (1) · Mapped (1) |
| Isolation of bovine liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase cDNA: bovine liver and heart forms of the enzyme are separate gene products. Lange A.J., El-Maghrabi M.R., Pilkis S.J.
Arch. Biochem. Biophys. 290:258-263(1991) · UniProtKB (1) |
| Cloning and sequencing of a cDNA encoding 2,3-bisphosphoglycerate-independent phosphoglycerate mutase from maize. Possible relationship to the alkaline phosphatase family. Grana X., de Lecea L., El-Maghrabi M.R., Urena J.M., Caellas C., Carreras J., Puigdomenech P., Pilkis S.J., Climent F.
J. Biol. Chem. 267:12797-12803(1992) · UniProtKB (1) |
