| Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. Guy M.P., Podyma B.M., Preston M.A., Shaheen H.H., Krivos K.L., Limbach P.A., Hopper A.K., Phizicky E.M.
RNA 18:1921-1933(2012) · UniProtKB (3) |
| Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase. Grant T.D., Snell E.H., Luft J.R., Quartley E., Corretore S., Wolfley J.R., Snell M.E., Hadd A., Perona J.J., Phizicky E.M. et al.
Nucleic Acids Res. 40:3723-3731(2012) · Mapped (1) |
| The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA. Whipple J.M., Lane E.A., Chernyakov I., D'Silva S., Phizicky E.M.
Genes Dev. 25:1173-1184(2011) · Mapped (1) |
| A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. D'Silva S., Haider S.J., Phizicky E.M.
RNA 17:1100-1110(2011) · Mapped (2) |
| The requirement for the highly conserved G-1 residue of Saccharomyces cerevisiae tRNAHis can be circumvented by overexpression of tRNAHis and its synthetase. Preston M.A., Phizicky E.M.
RNA 16:1068-1077(2010) · Mapped (2) |
| Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. Murthi A., Shaheen H.H., Huang H.Y., Preston M.A., Lai T.P., Phizicky E.M., Hopper A.K.
Mol. Biol. Cell 21:639-649(2010) · Mapped (6) |
| The use of Saccharomyces cerevisiae proteomic libraries to identify RNA-modifying proteins. Jackman J.E., Grayhack E.J., Phizicky E.M.
Methods Mol. Biol. 488:383-393(2008) · UniProtKB (1) |
| Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function. Merritt E.A., Holmes M., Buckner F.S., Van Voorhis W.C., Quartly E., Phizicky E.M., Lauricella A., Luft J., DeTitta G., Neely H. et al.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64:474-478(2008) · UniProtKB (1) |
| Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. Chernyakov I., Whipple J.M., Kotelawala L., Grayhack E.J., Phizicky E.M.
Genes Dev. 22:1369-1380(2008) · UniProtKB (1) · Mapped (9) |
| Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase. Jackman J.E., Phizicky E.M.
Biochemistry 47:4817-4825(2008) · Mapped (1) |
| Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species. Kotelawala L., Grayhack E.J., Phizicky E.M.
RNA 14:158-169(2008) · UniProtKB (1) · Mapped (1) |
| Identification and characterization of modification enzymes by biochemical analysis of the proteome. Jackman J.E., Kotelawala L., Grayhack E.J., Phizicky E.M.
Meth. Enzymol. 425:139-152(2007) · Mapped (1) |
| Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anomalous dispersion phasing. Malkowski M.G., Quartley E., Friedman A.E., Babulski J., Kon Y., Wolfley J., Said M., Luft J.R., Phizicky E.M., DeTitta G.T. et al.
Proc. Natl. Acad. Sci. U.S.A. 104:6678-6683(2007) · Mapped (4) |
| The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4. Wilkinson M.L., Crary S.M., Jackman J.E., Grayhack E.J., Phizicky E.M.
RNA 13:404-413(2007) · UniProtKB (1) |
| tRNAHis guanylyltransferase catalyzes a 3'-5' polymerization reaction that is distinct from G-1 addition. Jackman J.E., Phizicky E.M.
Proc. Natl. Acad. Sci. U.S.A. 103:8640-8645(2006) · Mapped (1) |
| tRNAHis guanylyltransferase adds G-1 to the 5' end of tRNAHis by recognition of the anticodon, one of several features unexpectedly shared with tRNA synthetases. Jackman J.E., Phizicky E.M.
RNA 12:1007-1014(2006) · Mapped (1) |
| Rapid tRNA decay can result from lack of nonessential modifications. Alexandrov A., Chernyakov I., Gu W., Hiley S.L., Hughes T.R., Grayhack E.J., Phizicky E.M.
Mol. Cell 21:87-96(2006) · UniProtKB (2) · Mapped (1) |
| Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C. Gu W., Hurto R.L., Hopper A.K., Grayhack E.J., Phizicky E.M.
Mol. Cell. Biol. 25:8191-8201(2005) · Mapped (8) |
| The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. Cartlidge R.A., Knebel A., Peggie M., Alexandrov A., Phizicky E.M., Cohen P.
EMBO J. 24:1696-1705(2005) · UniProtKB (2) · Mapped (1) |
| tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p. Alexandrov A., Grayhack E.J., Phizicky E.M.
RNA 11:821-830(2005) · UniProtKB (2) |
| A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae. Shull N.P., Spinelli S.L., Phizicky E.M.
Nucleic Acids Res. 33:650-660(2005) · UniProtKB (1) · Mapped (2) |
| Detection and discovery of RNA modifications using microarrays. Hiley S.L., Jackman J.E., Babak T., Trochesset M., Morris Q.D., Phizicky E.M., Hughes T.R.
Nucleic Acids Res. 33:E2-E2(2005) · UniProtKB (1) · Mapped (9) |
| Analysis of 2'-phosphotransferase (Tpt1p) from Saccharomyces cerevisiae: evidence for a conserved two-step reaction mechanism. Steiger M.A., Jackman J.E., Phizicky E.M.
RNA 11:99-106(2005) · Mapped (1) |
| The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs. Xing F., Hiley S.L., Hughes T.R., Phizicky E.M.
J. Biol. Chem. 279:17850-17860(2004) · UniProtKB (4) |
| tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis. Gu W., Jackman J.E., Lohan A.J., Gray M.W., Phizicky E.M.
Genes Dev. 17:2889-2901(2003) · UniProtKB (1) |
