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Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.

Vogtle F.N., Wortelkamp S., Zahedi R.P., Becker D., Leidhold C., Gevaert K., Kellermann J., Voos W., Sickmann A., Pfanner N. et al.

Cell 139:428-439(2009) · Mapped (42)

Mitochondrial F1Fo-ATP synthase: the small subunits e and g associate with monomeric complexes to trigger dimerization.

Wagner K., Rehling P., Sanjuan Szklarz L.K., Taylor R.D., Pfanner N., van der Laan M.

J. Mol. Biol. 392:855-861(2009) · Mapped (2)

The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis.

Kutik S., Rissler M., Guan X.L., Guiard B., Shui G., Gebert N., Heacock P.N., Rehling P., Dowhan W., Wenk M.R. et al.

J. Cell Biol. 183:1213-1221(2008) · Mapped (4)

Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase.

Stojanovski D., Milenkovic D., Muller J.M., Gabriel K., Schulze-Specking A., Baker M.J., Ryan M.T., Guiard B., Pfanner N., Chacinska A.

J. Cell Biol. 183:195-202(2008) · Mapped (2)

Mitochondrial biogenesis, switching the sorting pathway of the intermembrane space receptor Mia40.

Chacinska A., Guiard B., Muller J.M., Schulze-Specking A., Gabriel K., Kutik S., Pfanner N.

J. Biol. Chem. 283:29723-29729(2008) · Mapped (5)

The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases.

Wagner K., Gebert N., Guiard B., Brandner K., Truscott K.N., Wiedemann N., Pfanner N., Rehling P.

Mol. Cell. Biol. 28:4251-4260(2008) · Mapped (6)

Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase.

Gebert N., Chacinska A., Wagner K., Guiard B., Koehler C.M., Rehling P., Pfanner N., Wiedemann N.

EMBO Rep. 9:548-554(2008) · Mapped (3)

Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase.

Hutu D.P., Guiard B., Chacinska A., Becker D., Pfanner N., Rehling P., van der Laan M.

Mol. Biol. Cell 19:2642-2649(2008) · Mapped (9)

Dissecting membrane insertion of mitochondrial beta-barrel proteins.

Kutik S., Stojanovski D., Becker L., Becker T., Meinecke M., Kruger V., Prinz C., Meisinger C., Guiard B., Wagner R. et al.

Cell 132:1011-1024(2008) · Mapped (7)

Multiple pathways for sorting mitochondrial precursor proteins.

Bolender N., Sickmann A., Wagner R., Meisinger C., Pfanner N.

EMBO Rep. 9:42-49(2008) · Mapped (35)

Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain.

Wiedemann N., van der Laan M., Hutu D.P., Rehling P., Pfanner N.

J. Cell Biol. 179:1115-1122(2007) · Mapped (5)

Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins.

Stojanovski D., Guiard B., Kozjak-Pavlovic V., Pfanner N., Meisinger C.

J. Cell Biol. 179:881-893(2007) · Mapped (10)

Precursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space.

Muller J.M., Milenkovic D., Guiard B., Pfanner N., Chacinska A.

Mol. Biol. Cell 19:226-236(2008) · Mapped (2)

Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.

Becker T., Pfannschmidt S., Guiard B., Stojanovski D., Milenkovic D., Kutik S., Pfanner N., Meisinger C., Wiedemann N.

J. Biol. Chem. 283:120-127(2008) · Mapped (6)

The mitochondrial machinery for import of precursor proteins.

Gabriel K., Pfanner N.

Methods Mol. Biol. 390:99-117(2007) · Mapped (11)

Motor-free mitochondrial presequence translocase drives membrane integration of preproteins.

van der Laan M., Meinecke M., Dudek J., Hutu D.P., Lind M., Perschil I., Guiard B., Wagner R., Pfanner N., Rehling P.

Nat. Cell Biol. 9:1152-1159(2007) · Mapped (1)

Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

Reinders J., Wagner K., Zahedi R.P., Stojanovski D., Eyrich B., van der Laan M., Rehling P., Sickmann A., Pfanner N., Meisinger C.

Mol. Cell. Proteomics 6:1896-1906(2007) · UniProtKB (47) · Mapped (6)

Biogenesis of the essential Tim9-Tim10 chaperone complex of mitochondria: site-specific recognition of cysteine residues by the intermembrane space receptor Mia40.

Milenkovic D., Gabriel K., Guiard B., Schulze-Specking A., Pfanner N., Chacinska A.

J. Biol. Chem. 282:22472-22480(2007) · Mapped (4)

The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria.

Meisinger C., Pfannschmidt S., Rissler M., Milenkovic D., Becker T., Stojanovski D., Youngman M.J., Jensen R.E., Chacinska A., Guiard B. et al.

EMBO J. 26:2229-2239(2007) · UniProtKB (3) · Mapped (11)

Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins.

Sanjuan Szklarz L.K., Kozjak-Pavlovic V., Vogtle F.N., Chacinska A., Milenkovic D., Vogel S., Durr M., Westermann B., Guiard B., Martinou J.C. et al.

J. Mol. Biol. 368:44-54(2007) · Mapped (35)

A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria.

van der Laan M., Wiedemann N., Mick D.U., Guiard B., Rehling P., Pfanner N.

Curr. Biol. 16:2271-2276(2006) · Mapped (26)

The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes.

Albrecht R., Rehling P., Chacinska A., Brix J., Cadamuro S.A., Volkmer R., Guiard B., Pfanner N., Zeth K.

EMBO Rep. 7:1233-1238(2006) · Mapped (3)

Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway.

Gabriel K., Milenkovic D., Chacinska A., Mueller J., Guiard B., Pfanner N., Meisinger C.

J. Mol. Biol. 365:612-620(2007) · UniProtKB (3) · Mapped (9)

Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.

J. Proteome Res. 5:1543-1554(2006) · UniProtKB (44) · Mapped (852)

Tim50 maintains the permeability barrier of the mitochondrial inner membrane.

Meinecke M., Wagner R., Kovermann P., Guiard B., Mick D.U., Hutu D.P., Voos W., Truscott K.N., Chacinska A., Pfanner N. et al.

Science 312:1523-1526(2006) · Mapped (7)

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