1 - 25 of 44 results for author:"Pepys M.B." in Literature citations
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| Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use. Pepys M.B., Gallimore J.R., Lloyd J., Li Z., Graham D., Taylor G.W., Ellmerich S., Mangione P.P., Tennent G.A., Hutchinson W.L. et al. J. Immunol. Methods 384:92-102(2012) · Mapped (3) |
| Hereditary systemic amyloidosis due to Asp76Asn variant beta2-microglobulin. Valleix S., Gillmore J.D., Bridoux F., Mangione P.P., Dogan A., Nedelec B., Boimard M., Touchard G., Goujon J.M., Lacombe C. et al. N. Engl. J. Med. 366:2276-2283(2012) · Mapped (7) |
| Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. Mikolajek H., Kolstoe S.E., Pye V.E., Mangione P., Pepys M.B., Wood S.P. J. Mol. Recognit. 24:371-377(2011) · Mapped (3) |
| Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. Wensley F., Gao P., Burgess S., Kaptoge S., Di Angelantonio E., Shah T., Engert J.C., Clarke R., Davey-Smith G., Nordestgaard B.G. et al. BMJ 342:d548-d548(2011) · Mapped (2) |
| Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Kolstoe S.E., Mangione P.P., Bellotti V., Taylor G.W., Tennent G.A., Deroo S., Morrison A.J., Cobb A.J., Coyne A., McCammon M.G. et al. Proc. Natl. Acad. Sci. U.S.A. 107:20483-20488(2010) · Mapped (1) |
| Lack of effect of a single injection of human C-reactive protein on murine lupus or nephrotoxic nephritis. Carlucci F., Cook H.T., Garg A., Pepys M.B., Botto M. Arthritis Rheum. 62:245-249(2010) · Mapped (3) |
| Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component. Kolstoe S.E., Ridha B.H., Bellotti V., Wang N., Robinson C.V., Crutch S.J., Keir G., Kukkastenvehmas R., Gallimore J.R., Hutchinson W.L. et al. Proc. Natl. Acad. Sci. U.S.A. 106:7619-7623(2009) · Mapped (1) |
| Complement factor H binds to denatured rather than to native pentameric C-reactive protein. Hakobyan S., Harris C.L., van den Berg C.W., Fernandez-Alonso M.C., de Jorge E.G., de Cordoba S.R., Rivas G., Mangione P., Pepys M.B., Morgan B.P. J. Biol. Chem. 283:30451-30460(2008) · Mapped (6) |
| Transgenic human CRP is not pro-atherogenic, pro-atherothrombotic or pro-inflammatory in apoE-/- mice. Tennent G.A., Hutchinson W.L., Kahan M.C., Hirschfield G.M., Gallimore J.R., Lewin J., Sabin C.A., Dhillon A.P., Pepys M.B. Atherosclerosis 196:248-255(2008) · Mapped (2) |
| Normal circulating serum amyloid P component concentration in systemic sclerosis. Tennent G.A., Dziadzio M., Triantafillidou E., Davies P., Gallimore J.R., Denton C.P., Pepys M.B. Arthritis Rheum. 56:2013-2017(2007) · Mapped (1) |
| Beta-edge interactions in a pentadecameric human antibody V kappa domain. James L.C., Jones P.C., McCoy A., Tennent G.A., Pepys M.B., Famm K., Winter G. J. Mol. Biol. 367:603-608(2007) · UniProtKB (1) |
| Proinflammatory effects of bacterial recombinant human C-reactive protein are caused by contamination with bacterial products, not by C-reactive protein itself. Pepys M.B., Hawkins P.N., Kahan M.C., Tennent G.A., Gallimore J.R., Graham D., Sabin C.A., Zychlinsky A., de Diego J. Circ. Res. 97:e97-103(2005) · Mapped (17) |
| Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice. Hirschfield G.M., Gallimore J.R., Kahan M.C., Hutchinson W.L., Sabin C.A., Benson G.M., Dhillon A.P., Tennent G.A., Pepys M.B. Proc. Natl. Acad. Sci. U.S.A. 102:8309-8314(2005) · Mapped (15) |
| Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability. Clapp B.R., Hirschfield G.M., Storry C., Gallimore J.R., Stidwill R.P., Singer M., Deanfield J.E., MacAllister R.J., Pepys M.B., Vallance P. et al. Circulation 111:1530-1536(2005) · Mapped (2) |
| Autoimmunity and glomerulonephritis in mice with targeted deletion of the serum amyloid P component gene: SAP deficiency or strain combination? Gillmore J.D., Hutchinson W.L., Herbert J., Bybee A., Mitchell D.A., Hasserjian R.P., Yamamura K., Suzuki M., Sabin C.A., Pepys M.B. Immunology 112:255-264(2004) · Mapped (2) |
| Classical and alternative pathway complement activation are not required for reactive systemic AA amyloid deposition in mice. Hutchinson W.L., Herbert J., Botto M., Pepys M.B. Immunology 112:250-254(2004) · Mapped (14) |
| The structures of crystalline complexes of human serum amyloid P component with its carbohydrate ligand, the cyclic pyruvate acetal of galactose. Thompson D., Pepys M.B., Tickle I., Wood S. J. Mol. Biol. 320:1081-1086(2002) · Mapped (1) |
| Production of granulocyte colony-stimulating factor in the nonspecific acute phase response enhances host resistance to bacterial infection. Noursadeghi M., Bickerstaff M.C., Herbert J., Moyes D., Cohen J., Pepys M.B. J. Immunol. 169:913-919(2002) · Mapped (4) |
| Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis. Lachmann H.J., Booth D.R., Booth S.E., Bybee A., Gilbertson J.A., Gillmore J.D., Pepys M.B., Hawkins P.N. N. Engl. J. Med. 346:1786-1791(2002) · UniProtKB (4) |
| Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Pepys M.B., Herbert J., Hutchinson W.L., Tennent G.A., Lachmann H.J., Gallimore J.R., Lovat L.B., Bartfai T., Alanine A., Hertel C. et al. Nature 417:254-259(2002) · Mapped (5) |
| Influenza virus infection is not affected by serum amyloid P component. Herbert J., Hutchinson W.L., Carr J., Ives J., Jakob-Roetne R., Yamamura K., Suzuki M., Pepys M.B. Mol. Med. 8:9-15(2002) · Mapped (3) |
| Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Mabbott N.A., Bruce M.E., Botto M., Walport M.J., Pepys M.B. Nat. Med. 7:485-487(2001) · Mapped (14) |
| Role of serum amyloid P component in bacterial infection: protection of the host or protection of the pathogen. Noursadeghi M., Bickerstaff M.C., Gallimore J.R., Herbert J., Cohen J., Pepys M.B. Proc. Natl. Acad. Sci. U.S.A. 97:14584-14589(2000) · Mapped (2) |
| Human serum amyloid P component is a single uncomplexed pentamer in whole serum. Hutchinson W.L., Hohenester E., Pepys M.B. Mol. Med. 6:482-493(2000) |
| Molecular chaperone properties of serum amyloid P component. Coker A.R., Purvis A., Baker D., Pepys M.B., Wood S.P. FEBS Lett. 473:199-202(2000) |