| X-ray structure of human aromatase reveals an androgen-specific active site. Ghosh D., Griswold J., Erman M., Pangborn W.
J. Steroid Biochem. Mol. Biol. 118:197-202(2010) · Mapped (9) |
| Structural basis for androgen specificity and oestrogen synthesis in human aromatase. Ghosh D., Griswold J., Erman M., Pangborn W.
Nature 457:219-223(2009) · UniProtKB (1) · Mapped (8) |
| The structure of T6 bovine insulin. Smith G.D., Pangborn W.A., Blessing R.H.
Acta Crystallogr. D Biol. Crystallogr. 61:1476-1482(2005) · Mapped (1) |
| Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH. Cody V., Luft J.R., Pangborn W.
Acta Crystallogr. D 61:147-155(2005) · UniProtKB (2) |
| Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate. Cody V., Galitsky N., Luft J.R., Pangborn W., Gangjee A., Devraj R., Queener S.F., Blakley R.L.
Acta Crystallogr. D Biol. Crystallogr. 53:638-649(1997) · Mapped (1) |
| Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution. Wojtczak A., Cody V., Luft J.R., Pangborn W.
Acta Crystallogr. D Biol. Crystallogr. 52:758-765(1996) · Mapped (1) |
| Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Cody V., Luft J.R., Pangborn W., Gangjee A., Queener S.F.
Acta Crystallogr. D 60:646-655(2004) · UniProtKB (2) |
| Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Cody V., Luft J.R., Pangborn W., Gangjee A.
Acta Crystallogr. D 59:1603-1609(2003) · UniProtKB (1) |
| Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolate binary complex with human dihydrofolate reductase. Cody V., Galitsky N., Luft J.R., Pangborn W., Gangjee A.
Acta Crystallogr. D 59:654-661(2003) · UniProtKB (1) |
| Structure of human estrone sulfatase suggests functional roles of membrane association. Hernandez-Guzman F.G., Higashiyama T., Pangborn W., Osawa Y., Ghosh D.
J. Biol. Chem. 278:22989-22997(2003) · UniProtKB (1) · Mapped (2) |
| The structure of T6 human insulin at 1.0 A resolution. Smith G.D., Pangborn W.A., Blessing R.H.
Acta Crystallogr. D Biol. Crystallogr. 59:474-482(2003) · Mapped (2) |
| Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase. Cody V., Galitsky N., Luft J.R., Pangborn W., Queener S.F., Gangjee A.
Acta Crystallogr. D 58:1393-1399(2002) · UniProtKB (1) |
| Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH. Cody V., Galitsky N., Luft J.R., Pangborn W., Rosowsky A., Queener S.F.
Acta Crystallogr. D 58:946-954(2002) · UniProtKB (1) |
| Complex of rat transthyretin with tetraiodothyroacetic acid refined at 2.1 and 1.8 A resolution. Muziol T., Cody V., Luft J.R., Pangborn W., Wojtczak A.
Acta Biochim. Pol. 48:877-884(2001) · UniProtKB (1) |
| Structure of the insecticidal bacterial delta-endotoxin Cry3Bb1 of Bacillus thuringiensis. Galitsky N., Cody V., Wojtczak A., Ghosh D., Luft J.R., Pangborn W., English L.
Acta Crystallogr. D Biol. Crystallogr. 57:1101-1109(2001) · Mapped (1) |
| Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced? Smith G.D., Pangborn W.A., Blessing R.H.
Acta Crystallogr. D Biol. Crystallogr. 57:1091-1100(2001) · Mapped (1) |
| Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 A resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites. Wojtczak A., Cody V., Luft J.R., Pangborn W.
Acta Crystallogr. D Biol. Crystallogr. 57:1061-1070(2001) · Mapped (1) |
| Multiple conformations of catalytic serine and histidine in acetylxylan esterase at 0.90 A. Ghosh D., Sawicki M., Lala P., Erman M., Pangborn W., Eyzaguirre J., Gutierrez R., Joernvall H., Thiel D.J.
J. Biol. Chem. 276:11159-11166(2001) · UniProtKB (1) |
| R6 hexameric insulin complexed with m-cresol or resorcinol. Smith G.D., Ciszak E., Magrum L.A., Pangborn W.A., Blessing R.H.
Acta Crystallogr. D Biol. Crystallogr. 56:1541-1548(2000) · Mapped (1) |
| Crystal structure of bovine duodenase, a serine protease, with dual trypsin and chymotrypsin-like specificities. Pletnev V.Z., Zamolodchikova T.S., Pangborn W.A., Duax W.L.
Proteins 41:8-16(2000) · UniProtKB (1) |
| Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate. Cody V., Chan D., Galitsky N., Rak D., Luft J.R., Pangborn W., Queener S.F., Laughton C.A., Stevens M.F.
Biochemistry 39:3556-3564(2000) · UniProtKB (1) |
| Structure of Ustilago maydis killer toxin KP6 alpha-subunit. A multimeric assembly with a central pore. Li N., Erman M., Pangborn W., Duax W.L., Park C.M., Bruenn J., Ghosh D.
J. Biol. Chem. 274:20425-20431(1999) · UniProtKB (1) |
| Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Cody V., Galitsky N., Rak D., Luft J.R., Pangborn W., Queener S.F.
Biochemistry 38:4303-4312(1999) · UniProtKB (1) |
| Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase. Ghosh D., Erman M., Sawicki M., Lala P., Weeks D.R., Li N., Pangborn W., Thiel D.J., Joernvall H., Gutierrez R. et al.
Acta Crystallogr. D 55:779-784(1999) · UniProtKB (1) |
| Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents. Gangjee A., Vidwans A.P., Vasudevan A., Queener S.F., Kisliuk R.L., Cody V., Li R., Galitsky N., Luft J.R., Pangborn W.
J. Med. Chem. 41:3426-3434(1998) · UniProtKB (1) |
