| Protein conformational gating of enzymatic activity in xanthine oxidoreductase. Ishikita H., Eger B.T., Okamoto K., Nishino T., Pai E.F.
J. Am. Chem. Soc. 134:999-1009(2012) · Mapped (1) |
| Crystal structure of the passenger domain of the Escherichia coli autotransporter EspP. Khan S., Mian H.S., Sandercock L.E., Chirgadze N.Y., Pai E.F.
J. Mol. Biol. 413:985-1000(2011) · Mapped (1) |
| Relative and regional stabilities of the hamster, mouse, rabbit, and bovine prion proteins toward urea unfolding assessed by nuclear magnetic resonance and circular dichroism spectroscopies. Julien O., Chatterjee S., Bjorndahl T.C., Sweeting B., Acharya S., Semenchenko V., Chakrabartty A., Pai E.F., Wishart D.S., Sykes B.D. et al.
Biochemistry 50:7536-7545(2011) · Mapped (31) |
| Mapping the reaction coordinates of enzymatic defluorination. Chan P.W., Yakunin A.F., Edwards E.A., Pai E.F.
J. Am. Chem. Soc. 133:7461-7468(2011) · UniProtKB (1) |
| Novel interactions of fluorinated nucleotide derivatives targeting orotidine 5'-monophosphate decarboxylase. Lewis M., Meza-Avina M.E., Wei L., Crandall I.E., Bello A.M., Poduch E., Liu Y., Paige C.J., Kain K.C., Pai E.F. et al.
J. Med. Chem. 54:2891-2901(2011) · Mapped (1) |
| Crystal structure of metarhodopsin II. Choe H.W., Kim Y.J., Park J.H., Morizumi T., Pai E.F., Krauss N., Hofmann K.P., Scheerer P., Ernst O.P.
Nature 471:651-655(2011) · Mapped (2) |
| Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase. Kanjee U., Gutsche I., Alexopoulos E., Zhao B., El Bakkouri M., Thibault G., Liu K., Ramachandran S., Snider J., Pai E.F. et al.
EMBO J. 30:931-944(2011) · Mapped (1) |
| Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate. Okamoto K., Kawaguchi Y., Eger B.T., Pai E.F., Nishino T.
J. Am. Chem. Soc. 0:0-0(2010) · Mapped (2) |
| Prion disease susceptibility is affected by beta-structure folding propensity and local side-chain interactions in PrP. Khan M.Q., Sweeting B., Mulligan V.K., Arslan P.E., Cashman N.R., Pai E.F., Chakrabartty A.
Proc. Natl. Acad. Sci. U.S.A. 107:19808-19813(2010) · UniProtKB (1) |
| Crystal structure of a truncated urease accessory protein UreF from Helicobacter pylori. Lam R., Romanov V., Johns K., Battaile K.P., Wu-Brown J., Guthrie J.L., Hausinger R.P., Pai E.F., Chirgadze N.Y.
Proteins 78:2839-2848(2010) · Mapped (1) |
| Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase. Meza-Avina M.E., Wei L., Liu Y., Poduch E., Bello A.M., Mishra R.K., Pai E.F., Kotra L.P.
Bioorg. Med. Chem. 18:4032-4041(2010) · Mapped (2) |
| Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. Bello A.M., Konforte D., Poduch E., Furlonger C., Wei L., Liu Y., Lewis M., Pai E.F., Paige C.J., Kotra L.P.
J. Med. Chem. 52:1648-1658(2009) · UniProtKB (1) · Mapped (1) |
| Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase. Fujihashi M., Wei L., Kotra L.P., Pai E.F.
J. Mol. Biol. 387:1199-1210(2009) · Mapped (1) |
| Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. Julien J.P., Bryson S., Nieva J.L., Pai E.F.
J. Mol. Biol. 384:377-392(2008) · UniProtKB (1) · Mapped (2) |
| Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Thomson C.A., Bryson S., McLean G.R., Creagh A.L., Pai E.F., Schrader J.W.
EMBO J. 27:2592-2602(2008) · UniProtKB (1) · Mapped (3) |
| Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6. Bryson S., Julien J.P., Isenman D.E., Kunert R., Katinger H., Pai E.F.
J. Mol. Biol. 382:910-919(2008) · Mapped (3) |
| Crystallization and preliminary X-ray analysis of the inducible lysine decarboxylase from Escherichia coli. Alexopoulos E., Kanjee U., Snider J., Houry W.A., Pai E.F.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64:700-706(2008) · Mapped (1) |
| Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol. Okamoto K., Eger B.T., Nishino T., Pai E.F., Nishino T.
Nucleosides Nucleotides Nucleic Acids 27:888-893(2008) · Mapped (1) |
| Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase. Bello A.M., Poduch E., Liu Y., Wei L., Crandall I., Wang X., Dyanand C., Kain K.C., Pai E.F., Kotra L.P.
J. Med. Chem. 51:439-448(2008) · UniProtKB (1) |
| Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase. Asai R., Nishino T., Matsumura T., Okamoto K., Igarashi K., Pai E.F., Nishino T.
J. Biochem. 141:525-534(2007) · UniProtKB (1) |
| A potent, covalent inhibitor of orotidine 5'-monophosphate decarboxylase with antimalarial activity. Bello A.M., Poduch E., Fujihashi M., Amani M., Li Y., Crandall I., Hui R., Lee P.I., Kain K.C., Pai E.F. et al.
J. Med. Chem. 50:915-921(2007) · Mapped (1) |
| Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties. Garces R.G., Gillon W., Pai E.F.
Protein Sci. 16:176-188(2007) · UniProtKB (1) · Mapped (1) |
| A structural basis for Mg2+ homeostasis and the CorA translocation cycle. Payandeh J., Pai E.F.
EMBO J. 25:3762-3773(2006) · UniProtKB (1) · Mapped (1) |
| The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme. Payandeh J., Fujihashi M., Gillon W., Pai E.F.
J. Biol. Chem. 281:6070-6078(2006) · UniProtKB (1) |
| An unprecedented twist to ODCase catalytic activity. Fujihashi M., Bello A.M., Poduch E., Wei L., Annedi S.C., Pai E.F., Kotra L.P.
J. Am. Chem. Soc. 127:15048-15050(2005) · UniProtKB (1) |
