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Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial cells.

Kusuhara S., Fukushima Y., Fukuhara S., Jakt L.M., Okada M., Shimizu Y., Hata M., Nishida K., Negi A., Hirashima M. et al.

PLoS ONE 7:e45858-e45858(2012) · Mapped (14)

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.

Kaji T., Ishige A., Hikida M., Taka J., Hijikata A., Kubo M., Nagashima T., Takahashi Y., Kurosaki T., Okada M. et al.

J. Exp. Med. 209:2079-2097(2012) · Mapped (9)

Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.

Sekine S., Kanamaru Y., Koike M., Nishihara A., Okada M., Kinoshita H., Kamiyama M., Maruyama J., Uchiyama Y., Ishihara N. et al.

J. Biol. Chem. 287:34635-34645(2012) · Mapped (1)

Non-small-cell lung cancer prognosis using carcinoembryonic antigen levels in pleural lavage fluid.

Tsutani Y., Yamashita Y., Misumi K., Ikeda T., Miyata Y., Okada M.

Eur J Cardiothorac Surg 42:e96-101(2012) · Mapped (7)

Cathepsin D as a potential prognostic marker for lung adenocarcinoma.

Mimae T., Tsuta K., Maeshima A.M., Okada M., Asamura H., Kondo T., Tsuda H.

Pathol. Res. Pract. 208:534-540(2012) · Mapped (1)

A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells.

Phalitakul S., Okada M., Hara Y., Yamawaki H.

Biochem. Biophys. Res. Commun. 423:844-849(2012) · Mapped (2)

A novel adipocytokine, chemerin exerts anti-inflammatory roles in human vascular endothelial cells.

Yamawaki H., Kameshima S., Usui T., Okada M., Hara Y.

Biochem. Biophys. Res. Commun. 423:152-157(2012) · Mapped (1)

Omentin plays an anti-inflammatory role through inhibition of TNF-alpha-induced superoxide production in vascular smooth muscle cells.

Kazama K., Usui T., Okada M., Hara Y., Yamawaki H.

Eur. J. Pharmacol. 686:116-123(2012) · Mapped (2)

DGKzeta is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway.

Okada M., Hozumi Y., Iwazaki K., Misaki K., Yanagida M., Araki Y., Watanabe T., Yagisawa H., Topham M.K., Kaibuchi K. et al.

Biochem. Biophys. Res. Commun. 420:479-484(2012) · Mapped (30)

Translational regulation by the 5'-UTR of thyroid hormone receptor alpha mRNA.

Okada M., Nakajima K., Yaoita Y.

J. Biochem. 151:519-531(2012) · UniProtKB (7)

Galectin-7 as a marker of cholesteatoma residue and its detection during surgery by an immunofluorescent method--a preliminary study.

Takagi D., Hato N., Okada M., Hakuba N., Gyo K., Shigemoto K., Toda T., Ogasawara M., Kameda K.

Otol. Neurotol. 33:396-399(2012) · Mapped (1)

Aberrant methylation and decreased expression of the RIZ1 gene are frequent in adult acute lymphoblastic leukemia of T-cell phenotype.

Shimura H., Mori N., Wang Y.H., Okada M., Motoji T.

Leuk. Lymphoma 53:1599-1609(2012) · Mapped (5)

MIG-13 controls anteroposterior cell migration by interacting with UNC-71/ADM-1 and SRC-1 in Caenorhabditis elegans.

Masuda H., Nakamura K., Takata N., Itoh B., Hirose T., Moribe H., Mekada E., Okada M.

FEBS Lett. 586:740-746(2012) · Mapped (4)

A novel adipocytokine, nesfatin-1 modulates peripheral arterial contractility and blood pressure in rats.

Yamawaki H., Takahashi M., Mukohda M., Morita T., Okada M., Hara Y.

Biochem. Biophys. Res. Commun. 418:676-681(2012) · UniProtKB (1)

Interferon (alpha, beta and omega) receptor 2 is a prognostic biomarker for lung cancer.

Tanaka S., Hattori N., Ishikawa N., Horimasu Y., Deguchi N., Takano A., Tomoda Y., Yoshioka K., Fujitaka K., Arihiro K. et al.

Pathobiology 79:24-33(2012) · Mapped (2)

The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes.

Takahashi Y., Nada S., Mori S., Soma-Nagae T., Oneyama C., Okada M.

Biochem. Biophys. Res. Commun. 417:1151-1157(2012) · Mapped (4)

Upregulation of notch2 and six1 is associated with progression of early-stage lung adenocarcinoma and a more aggressive phenotype at advanced stages.

Mimae T., Okada M., Hagiyama M., Miyata Y., Tsutani Y., Inoue T., Murakami Y., Ito A.

Clin. Cancer Res. 18:945-955(2012) · Mapped (7)

Dysfunction of extrasynaptic GABAergic transmission in phospholipase C-related, but catalytically inactive protein 1 knockout mice is associated with an epilepsy phenotype.

Zhu G., Yoshida S., Migita K., Yamada J., Mori F., Tomiyama M., Wakabayashi K., Kanematsu T., Hirata M., Kaneko S. et al.

J. Pharmacol. Exp. Ther. 340:520-528(2012) · Mapped (2)

Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression.

Yamagata K., Li X., Ikegaki S., Oneyama C., Okada M., Nishita M., Minami Y.

J. Biol. Chem. 287:1588-1599(2012) · Mapped (28)

Interleukin-6 gene promoter methylation in rheumatoid arthritis and chronic periodontitis.

Ishida K., Kobayashi T., Ito S., Komatsu Y., Yokoyama T., Okada M., Abe A., Murasawa A., Yoshie H.

J. Periodontol. 83:917-925(2012) · Mapped (5)

Interaction of nucleosome assembly proteins abolishes nuclear localization of DGKzeta by attenuating its association with importins.

Okada M., Hozumi Y., Ichimura T., Tanaka T., Hasegawa H., Yamamoto M., Takahashi N., Iseki K., Yagisawa H., Shinkawa T. et al.

Exp. Cell Res. 317:2853-2863(2011) · Mapped (12)

Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus.

Tanahashi S., Yamamura S., Nakagawa M., Motomura E., Okada M.

Psychopharmacology (Berl.) 220:599-610(2012) · Mapped (1)

Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice.

Morita M., Oike Y., Nagashima T., Kadomatsu T., Tabata M., Suzuki T., Nakamura T., Yoshida N., Okada M., Yamamoto T.

EMBO J. 30:4678-4691(2011) · UniProtKB (1) · Mapped (4)

Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.

Yoshida S., Hong S., Suzuki T., Nada S., Mannan A.M., Wang J., Okada M., Guan K.L., Inoki K.

J. Biol. Chem. 286:32651-32660(2011) · Mapped (15)

Vaspin prevents TNF-alpha-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-kappaB and PKCtheta activation in cultured rat vascular smooth muscle cells.

Phalitakul S., Okada M., Hara Y., Yamawaki H.

Pharmacol. Res. 64:493-500(2011) · Mapped (7)

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