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Papillary hyperplasia of the gallbladder in pancreaticobiliary maljunction represents a senescence-related lesion induced by lysolecithin.

Yamaguchi J., Sasaki M., Harada K., Zen Y., Sato Y., Ikeda H., Itatsu K., Yokoyama Y., Ando H., Ohta T. et al.

Lab. Invest. 89:1018-1031(2009) · Mapped (13)

Local angiotensin II-generation in human gastric cancer: correlation with tumor progression through the activation of ERK1/2, NF-kappaB and survivin.

Kinoshita J., Fushida S., Harada S., Yagi Y., Fujita H., Kinami S., Ninomiya I., Fujimura T., Kayahara M., Yashiro M. et al.

Int. J. Oncol. 34:1573-1582(2009) · Mapped (4)

The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa.

Niimi N., Sassa A., Katafuchi A., Gruz P., Fujimoto H., Bonala R.R., Johnson F., Ohta T., Nohmi T.

Biochemistry 48:4239-4246(2009) · Mapped (6)

High affinity interaction between histidine-rich glycoprotein and the cell surface type ATP synthase on T-cells.

Ohta T., Ikemoto Y., Usami A., Koide T., Wakabayashi S.

Biochim. Biophys. Acta 1788:1099-1107(2009) · Mapped (3)

Lipopolysaccharides enhance the action of bradykinin in enteric neurons via secretion of interleukin-1beta from enteric glial cells.

Murakami M., Ohta T., Ito S.

J. Neurosci. Res. 87:2095-2104(2009) · Mapped (1)

Cyclooxygenase-2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha.

Itatsu K., Sasaki M., Yamaguchi J., Ohira S., Ishikawa A., Ikeda H., Sato Y., Harada K., Zen Y., Sato H. et al.

Am. J. Pathol. 174:829-841(2009) · Mapped (10)

PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt.

Kawase T., Ohki R., Shibata T., Tsutsumi S., Kamimura N., Inazawa J., Ohta T., Ichikawa H., Aburatani H., Tashiro F. et al.

Cell 136:535-550(2009) · UniProtKB (2) · Mapped (38)

Adenylate cyclase-associated protein 1 overexpressed in pancreatic cancers is involved in cancer cell motility.

Yamazaki K., Takamura M., Masugi Y., Mori T., Du W., Hibi T., Hiraoka N., Ohta T., Ohki M., Hirohashi S. et al.

Lab. Invest. 89:425-432(2009) · Mapped (17)

Expression of Aurora B and alternative variant forms in hepatocellular carcinoma and adjacent tissue.

Yasen M., Mizushima H., Mogushi K., Obulhasim G., Miyaguchi K., Inoue K., Nakahara I., Ohta T., Aihara A., Tanaka S. et al.

Cancer Sci. 100:472-480(2009) · UniProtKB (3) · Mapped (3)

The ratio of high-molecular weight adiponectin and total adiponectin differs in preterm and term infants.

Yoshida T., Nagasaki H., Asato Y., Ohta T.

Pediatr. Res. 65:580-583(2009) · Mapped (3)

BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.

Nishikawa H., Wu W., Koike A., Kojima R., Gomi H., Fukuda M., Ohta T.

Cancer Res. 69:111-119(2009) · Mapped (43)

Developmentally dynamic changes of DNA methylation in the mouse Snurf/Snrpn gene.

Miyazaki K., Mapendano C.K., Fuchigami T., Kondo S., Ohta T., Kinoshita A., Tsukamoto K., Yoshiura K., Niikawa N., Kishino T.

Gene 432:97-101(2009) · Mapped (4)

Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant.

Mukai Y., Shibata H., Nakamura T., Yoshioka Y., Abe Y., Nomura T., Taniai M., Ohta T., Ikemizu S., Nakagawa S. et al.

J. Mol. Biol. 385:1221-1229(2009) · Mapped (8)

Possible involvement of caspase-6 and -7 but not caspase-3 in the regulation of hypoxia-induced apoptosis in tube-forming endothelial cells.

Eguchi R., Tone S., Suzuki A., Fujimori Y., Nakano T., Kaji K., Ohta T.

Exp. Cell Res. 315:327-335(2009) · Mapped (8)

Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma.

Ninomiya I., Kawakami K., Fushida S., Fujimura T., Funaki H., Takamura H., Kitagawa H., Nakagawara H., Tajima H., Kayahara M. et al.

Oncol. Rep. 20:1489-1495(2008) · Mapped (4)

Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.

Dohi Y., Ikura T., Hoshikawa Y., Katoh Y., Ota K., Nakanome A., Muto A., Omura S., Ohta T., Ito A. et al.

Nat. Struct. Mol. Biol. 15:1246-1254(2008) · Mapped (21)

Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma.

Yamashita T., Honda M., Takatori H., Nishino R., Minato H., Takamura H., Ohta T., Kaneko S.

J. Hepatol. 50:100-110(2009) · Mapped (9)

The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models.

Shibata H., Yoshioka Y., Ohkawa A., Abe Y., Nomura T., Mukai Y., Nakagawa S., Taniai M., Ohta T., Mayumi T. et al.

Cytokine 44:229-233(2008) · Mapped (12)

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.

Shibata T., Ohta T., Tong K.I., Kokubu A., Odogawa R., Tsuta K., Asamura H., Yamamoto M., Hirohashi S.

Proc. Natl. Acad. Sci. U.S.A. 105:13568-13573(2008) · Mapped (12)

IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver.

Hamada S., Umemura M., Shiono T., Tanaka K., Yahagi A., Begum M.D., Oshiro K., Okamoto Y., Watanabe H., Kawakami K. et al.

J. Immunol. 181:3456-3463(2008) · Mapped (3)

Phosphorylation of extracellular signal-regulated kinase 1/2, p38 mitogen-activated protein kinase and nuclear translocation of nuclear factor-kappaB are involved in upregulation of matrix metalloproteinase-9 by tumour necrosis factor-alpha.

Itatsu K., Sasaki M., Harada K., Yamaguchi J., Ikeda H., Sato Y., Ohta T., Sato H., Nagino M., Nimura Y. et al.

Liver Int. 29:291-298(2009) · Mapped (6)

Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer.

Shibata T., Kokubu A., Gotoh M., Ojima H., Ohta T., Yamamoto M., Hirohashi S.

Gastroenterology 135:1358-1368, 2008:1368.e1-4(2008) · Mapped (8)

Structural basis for multimeric heme complexation through a specific protein-heme interaction: the case of the third neat domain of IsdH from Staphylococcus aureus.

Watanabe M., Tanaka Y., Suenaga A., Kuroda M., Yao M., Watanabe N., Arisaka F., Ohta T., Tanaka I., Tsumoto K.

J. Biol. Chem. 283:28649-28659(2008) · Mapped (2)

Expression profile of early lung adenocarcinoma: identification of MRP3 as a molecular marker for early progression.

Hanada S., Maeshima A., Matsuno Y., Ohta T., Ohki M., Yoshida T., Hayashi Y., Yoshizawa Y., Hirohashi S., Sakamoto M.

J. Pathol. 216:75-82(2008) · Mapped (7)

The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma.

Sasaki M., Ikeda H., Itatsu K., Yamaguchi J., Sawada S., Minato H., Ohta T., Nakanuma Y.

Lab. Invest. 88:873-882(2008) · Mapped (22)

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