| Loss of cleavage at beta'-site contributes to apparent increase in beta-amyloid peptide (Abeta) secretion by beta-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of amyloid precursor protein. Vetrivel K.S., Barman A., Chen Y., Nguyen P.D., Wagner S.L., Prabhakar R., Thinakaran G.
J. Biol. Chem. 286:26166-26177(2011) · Mapped (27) |
| Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of gamma-secretase activity toward amyloid precursor protein and other substrates. Gong P., Vetrivel K.S., Nguyen P.D., Meckler X., Cheng H., Kounnas M.Z., Wagner S.L., Parent A.T., Thinakaran G.
J. Biol. Chem. 285:38042-38052(2010) · Mapped (9) |
| Rapid identification of the hepatic cytochrome P450 2C19 activity using a novel and noninvasive [13C]pantoprazole breath test. Desta Z., Modak A., Nguyen P.D., Lemler S.M., Kurogi Y., Li L., Flockhart D.A.
J. Pharmacol. Exp. Ther. 329:297-305(2009) · Mapped (10) |
| Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. Vetrivel K.S., Meckler X., Chen Y., Nguyen P.D., Seidah N.G., Vassar R., Wong P.C., Fukata M., Kounnas M.Z., Thinakaran G.
J. Biol. Chem. 284:3793-3803(2009) · Mapped (36) |
| Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A. Jeong S., Nguyen P.D., Desta Z.
Antimicrob. Agents Chemother. 53:541-551(2009) |
| Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism. Vetrivel K.S., Gong P., Bowen J.W., Cheng H., Chen Y., Carter M., Nguyen P.D., Placanica L., Wieland F.T., Li Y.M. et al.
Mol. Neurodegener. 2:4-4(2007) · UniProtKB (1) |
| Disulfide bond formation promotes the cis- and trans-dimerization of the E-cadherin-derived first repeat. Makagiansar I.T., Nguyen P.D., Ikesue A., Kuczera K., Dentler W., Urbauer J.L., Galeva N., Alterman M., Siahaan T.J.
J. Biol. Chem. 277:16002-16010(2002) · UniProtKB (1) · Mapped (5) |
