| The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity. Kunkel M.T., Garcia E.L., Kajimoto T., Hall R.A., Newton A.C.
J. Biol. Chem. 284:24653-24661(2009) · Mapped (12) |
| Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C. Brognard J., Niederst M., Reyes G., Warfel N., Newton A.C.
J. Biol. Chem. 284:15215-15223(2009) · Mapped (15) |
| The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail. Gould C.M., Kannan N., Taylor S.S., Newton A.C.
J. Biol. Chem. 284:4921-4935(2009) · Mapped (7) |
| AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Carnegie G.K., Soughayer J., Smith F.D., Pedroja B.S., Zhang F., Diviani D., Bristow M.R., Kunkel M.T., Newton A.C., Langeberg L.K. et al.
Mol. Cell 32:169-179(2008) · Mapped (1) |
| The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. Facchinetti V., Ouyang W., Wei H., Soto N., Lazorchak A., Gould C., Lowry C., Newton A.C., Mao Y., Miao R.Q. et al.
EMBO J. 27:1932-1943(2008) · Mapped (15) |
| PHLiPPing the switch on Akt and protein kinase C signaling. Brognard J., Newton A.C.
Trends Endocrinol. Metab. 19:223-230(2008) · Mapped (2) |
| The phosphatase PHLPP controls the cellular levels of protein kinase C. Gao T., Brognard J., Newton A.C.
J. Biol. Chem. 283:6300-6311(2008) · UniProtKB (3) · Mapped (1) |
| Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase. Chen D., Gould C., Garza R., Gao T., Hampton R.Y., Newton A.C.
J. Biol. Chem. 282:33776-33787(2007) · UniProtKB (2) · Mapped (12) |
| PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms. Brognard J., Sierecki E., Gao T., Newton A.C.
Mol. Cell 25:917-931(2007) · UniProtKB (2) · Mapped (8) |
| Systematics and morphological evolution within the moss family Bryaceae: a comparison between parsimony and Bayesian methods for reconstruction of ancestral character states. Pedersen N., Holyoak D.T., Newton A.E.
Mol. Phylogenet. Evol. 43:891-907(2007) · UniProtKB (30) |
| Real-time imaging of Rab3a and Rab5a reveals differential roles in presynaptic function. Star E.N., Newton A.J., Murthy V.N.
J. Physiol. (Lond.) 569:103-117(2005) · Mapped (1) |
| PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Gao T., Furnari F., Newton A.C.
Mol. Cell 18:13-24(2005) · UniProtKB (4) · Mapped (7) |
| Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter. Kunkel M.T., Ni Q., Tsien R.Y., Zhang J., Newton A.C.
J. Biol. Chem. 280:5581-5587(2005) · Mapped (4) |
| The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1. King C.C., Newton A.C.
J. Biol. Chem. 279:37518-37527(2004) · Mapped (14) |
| Centrosomal anchoring of protein kinase C betaII by pericentrin controls microtubule organization, spindle function, and cytokinesis. Chen D., Purohit A., Halilovic E., Doxsey S.J., Newton A.C.
J. Biol. Chem. 279:4829-4839(2004) · Mapped (1) |
| Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Pizzuti A., Sarkozy A., Newton A.L., Conti E., Flex E., Digilio M.C., Amati F., Gianni D., Tandoi C., Marino B. et al.
Hum. Mutat. 22:372-377(2003) · UniProtKB (1) |
| SulP, a nuclear gene encoding a putative chloroplast-targeted sulfate permease in Chlamydomonas reinhardtii. Chen H.C., Yokthongwattana K., Newton A.J., Melis A.
Planta 218:98-106(2003) · UniProtKB (1) |
| A Ras activation pathway dependent on Syk phosphorylation of protein kinase C. Kawakami Y., Kitaura J., Yao L., McHenry R.W., Kawakami Y., Newton A.C., Kang S., Kato R.M., Leitges M., Rawlings D.J. et al.
Proc. Natl. Acad. Sci. U.S.A. 100:9470-9475(2003) · Mapped (4) |
| Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Eisbacher M., Holmes M.L., Newton A., Hogg P.J., Khachigian L.M., Crossley M., Chong B.H.
Mol. Cell. Biol. 23:3427-3441(2003) · Mapped (7) |
| Crystallographic and biochemical studies of DivK reveal novel features of an essential response regulator in Caulobacter crescentus. Guillet V., Ohta N., Cabantous S., Newton A., Samama J.P.
J. Biol. Chem. 277:42003-42010(2002) · UniProtKB (1) · Mapped (1) |
| The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C. Gao T., Newton A.C.
J. Biol. Chem. 277:31585-31592(2002) · Mapped (2) |
| Data sets, partitions, and characters: philosophies and procedures for analyzing multiple data sets. Ballard J.W., Thayer M.K., Newton A.F. Jr., Grismer E.R.
Syst. Biol. 47:367-396(1998) · UniProtKB (22) |
| A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution. Sharpe B.K., Matthews J.M., Kwan A.H., Newton A., Gell D.A., Crossley M., Mackay J.P.
Structure 10:639-648(2002) · Mapped (5) |
| Regulation of novel protein kinase C epsilon by phosphorylation. Cenni V., Doeppler H., Sonnenburg E.D., Maraldi N., Newton A.C., Toker A.
Biochem. J. 363:537-545(2002) · UniProtKB (1) · Mapped (11) |
| PKA, PKC, and AKAP localization in and around the neuromuscular junction. Perkins G.A., Wang L., Huang L.J., Humphries K., Yao V.J., Martone M., Deerinck T.J., Barraclough D.M., Violin J.D., Smith D. et al.
BMC Neurosci 2:17-17(2001) · Mapped (1) |
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