| Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice. Kawashima T., Inuzuka Y., Okuda J., Kato T., Niizuma S., Tamaki Y., Iwanaga Y., Kawamoto A., Narazaki M., Matsuda T. et al.
J. Mol. Cell. Cardiol. 51:1026-1036(2011) · Mapped (6) |
| Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A. Narazaki M., Segarra M., Tosato G.
Blood 111:4126-4136(2008) · Mapped (24) |
| Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Narazaki M., Tosato G.
Blood 107:3892-3901(2006) · Mapped (14) |
| Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation. Davis D.A., Singer K.E., De La Luz Sierra M., Narazaki M., Yang F., Fales H.M., Yarchoan R., Tosato G.
Blood 105:4561-4568(2005) · Mapped (7) |
| Differential processing of stromal-derived factor-1alpha and beta explains functional diversity. De La Luz Sierra M., Yang F., Narazaki M., Salvucci O., Davis D., Yarchoan R., Zhang H.H., Fales H., Tosato G.
Blood 103:2452-2459(2004) · UniProtKB (1) · Mapped (1) |
| SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo. Naka T., Tsutsui H., Fujimoto M., Kawazoe Y., Kohzaki H., Morita Y., Nakagawa R., Narazaki M., Adachi K., Yoshimoto T. et al.
Immunity 14:535-545(2001) · Mapped (22) |
| Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation. Kawazoe Y., Naka T., Fujimoto M., Kohzaki H., Morita Y., Narazaki M., Okumura K., Saitoh H., Nakagawa R., Uchiyama Y. et al.
J. Exp. Med. 193:263-269(2001) · Mapped (1) |
| Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts. Morita Y., Naka T., Kawazoe Y., Fujimoto M., Narazaki M., Nakagawa R., Fukuyama H., Nagata S., Kishimoto T.
Proc. Natl. Acad. Sci. U.S.A. 97:5405-5410(2000) · Mapped (1) |
| Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. Naka T., Matsumoto T., Narazaki M., Fujimoto M., Morita Y., Ohsawa Y., Saito H., Nagasawa T., Uchiyama Y., Kishimoto T.
Proc. Natl. Acad. Sci. U.S.A. 95:15577-15582(1998) · Mapped (1) |
| Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling. Narazaki M., Fujimoto M., Matsumoto T., Morita Y., Saito H., Kajita T., Yoshizaki K., Naka T., Kishimoto T.
Proc. Natl. Acad. Sci. U.S.A. 95:13130-13134(1998) · UniProtKB (1) |
| Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3. Minamoto S., Ikegame K., Ueno K., Narazaki M., Naka T., Yamamoto H., Matsumoto T., Saito H., Hosoe S., Kishimoto T.
Biochem. Biophys. Res. Commun. 237:79-83(1997) · UniProtKB (3) · Mapped (2) |
| Structure and function of a new STAT-induced STAT inhibitor. Naka T., Narazaki M., Hirata M., Matsumoto T., Minamoto S., Aono A., Nishimoto N., Kajita T., Taga T., Yoshizaki K. et al.
Nature 387:924-929(1997) · UniProtKB (1) |
| Vav is associated with signal transducing molecules gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6. Lee I.S., Liu Y., Narazaki M., Hibi M., Kishimoto T., Taga T.
FEBS Lett. 401:133-137(1997) · Mapped (22) |
| Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal. Suzuki H., Yasukawa K., Saito T., Narazaki M., Hasegawa A., Taga T., Kishimoto T.
Eur. J. Immunol. 23:1078-1082(1993) · Mapped (5) |
| Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130. Narazaki M., Yasukawa K., Saito T., Ohsugi Y., Fukui H., Koishihara Y., Yancopoulos G.D., Taga T., Kishimoto T.
Blood 82:1120-1126(1993) |